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Article: Oestradiol binding activity in rat liver tumours and in human hepatocellular carcinoma

TitleOestradiol binding activity in rat liver tumours and in human hepatocellular carcinoma
Authors
Alagaratnam, TTWei, WWong, J
Keywordsexperimental
liver neoplasms
oestradiol
oestrogen
receptors.
Issue Date1987
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANS
Citation
Australian And New Zealand Journal Of Surgery, 1987, v. 57 n. 7, p. 477-479 How to Cite?
DOI: http://dx.doi.org/10.1111/j.1445-2197.1987.tb01402.x
AbstractOestradiol binding acitvity was studied in normal liver tissues of rats as well as as in experimentally induced liver tumours by incubating a cytosol prepared from the tissue with radioactive oestradiol. The free radioactive hormone was absorbed by a dextran-charcoal suspension, and the amount required to saturate the receptors was calculated by a Scatchard plot. Similar activity was observed in normal human liver as well as in naturally occurring hepatocellular carcinoma.
Persistent Identifierhttp://hdl.handle.net/10722/172569
ISSN
0004-8682
2020 SCImago Journal Rankings: 0.111
ISI Accession Number ID
WOS:A1987J200800014

 

DC FieldValueLanguage
dc.contributor.authorAlagaratnam, TTen_HK
dc.contributor.authorWei, Wen_HK
dc.contributor.authorWong, Jen_HK
dc.date.accessioned2012-10-30T06:23:27Z-
dc.date.available2012-10-30T06:23:27Z-
dc.date.issued1987en_HK
dc.identifier.citationAustralian And New Zealand Journal Of Surgery, 1987, v. 57 n. 7, p. 477-479en_HK
dc.identifier.issn0004-8682en_HK
dc.identifier.urihttp://hdl.handle.net/10722/172569-
dc.description.abstractOestradiol binding acitvity was studied in normal liver tissues of rats as well as as in experimentally induced liver tumours by incubating a cytosol prepared from the tissue with radioactive oestradiol. The free radioactive hormone was absorbed by a dextran-charcoal suspension, and the amount required to saturate the receptors was calculated by a Scatchard plot. Similar activity was observed in normal human liver as well as in naturally occurring hepatocellular carcinoma.en_HK
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANSen_HK
dc.relation.ispartofAustralian and New Zealand Journal of Surgeryen_HK
dc.subjectexperimental-
dc.subjectliver neoplasms-
dc.subjectoestradiol-
dc.subjectoestrogen-
dc.subjectreceptors.-
dc.subject.meshAnimalsen_US
dc.subject.meshCarcinoma, Hepatocellular - Metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver - Metabolismen_US
dc.subject.meshLiver Neoplasms - Metabolismen_US
dc.subject.meshLiver Neoplasms, Experimental - Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshRadioligand Assayen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.subject.meshReceptors, Estradiol - Metabolismen_US
dc.subject.meshReceptors, Estrogen - Metabolismen_US
dc.titleOestradiol binding activity in rat liver tumours and in human hepatocellular carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailWei, W: hrmswwi@hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityWei, W=rp00323en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1445-2197.1987.tb01402.x-
dc.identifier.pmid3038066-
dc.identifier.scopuseid_2-s2.0-0023598270en_HK
dc.identifier.volume57en_HK
dc.identifier.issue7en_HK
dc.identifier.spage477en_HK
dc.identifier.epage479en_HK
dc.identifier.isiWOS:A1987J200800014-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridAlagaratnam, TT=7003566659en_HK
dc.identifier.scopusauthoridWei, W=7403321552en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK
dc.identifier.issnl0004-8682-

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