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Article: The bacteriology and septic complication of patients with appendicitis

TitleThe bacteriology and septic complication of patients with appendicitis
Authors
Issue Date1984
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.com
Citation
Annals Of Surgery, 1984, v. 200 n. 5, p. 576-581 How to Cite?
AbstractA detailed bacteriologic study was done on 161 patients operated for appendicitis. Aerobic and anaerobic cultures were taken from the blood, the appendicular lumen, mucosa, serosa, fossa, and from the wound after closure of the peritoneum. There is no correlation between the degree of appendicitis and the incidence of positive blood culture. The infection spread through the appendicular wall as the disease progressed. Aerobic infection was common in early appendicitis but a mixed aerobic and anaerobic infection was predominant in late cases. Late appendicitis, a positive wound culture at the end of the operation, the duration of symptoms of over 36 hours before operation and the age of the patient over 50 years were all associated with an increased incidence of septic complication. From the antibiotic sensitivity on the bacteria isolated, the most effective agent against anaerobes was metronidazole. Effective agents against the aerobes were aminoglycosides and cephalosporins. The best single agent against both anaerobes and aerobes was moxalactum.
Persistent Identifierhttp://hdl.handle.net/10722/172532
ISSN
2015 Impact Factor: 8.569
2015 SCImago Journal Rankings: 4.503
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, WYen_US
dc.contributor.authorTeohChan, CHen_US
dc.contributor.authorFan, STen_US
dc.date.accessioned2012-10-30T06:23:16Z-
dc.date.available2012-10-30T06:23:16Z-
dc.date.issued1984en_US
dc.identifier.citationAnnals Of Surgery, 1984, v. 200 n. 5, p. 576-581en_US
dc.identifier.issn0003-4932en_US
dc.identifier.urihttp://hdl.handle.net/10722/172532-
dc.description.abstractA detailed bacteriologic study was done on 161 patients operated for appendicitis. Aerobic and anaerobic cultures were taken from the blood, the appendicular lumen, mucosa, serosa, fossa, and from the wound after closure of the peritoneum. There is no correlation between the degree of appendicitis and the incidence of positive blood culture. The infection spread through the appendicular wall as the disease progressed. Aerobic infection was common in early appendicitis but a mixed aerobic and anaerobic infection was predominant in late cases. Late appendicitis, a positive wound culture at the end of the operation, the duration of symptoms of over 36 hours before operation and the age of the patient over 50 years were all associated with an increased incidence of septic complication. From the antibiotic sensitivity on the bacteria isolated, the most effective agent against anaerobes was metronidazole. Effective agents against the aerobes were aminoglycosides and cephalosporins. The best single agent against both anaerobes and aerobes was moxalactum.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.annalsofsurgery.comen_US
dc.relation.ispartofAnnals of Surgeryen_US
dc.subject.meshAnti-Bacterial Agents - Pharmacology - Therapeutic Useen_US
dc.subject.meshAppendectomyen_US
dc.subject.meshAppendicitis - Microbiology - Pathology - Surgeryen_US
dc.subject.meshBacteria - Drug Effects - Isolation & Purificationen_US
dc.subject.meshBacteria, Aerobic - Isolation & Purificationen_US
dc.subject.meshBacteria, Anaerobic - Isolation & Purificationen_US
dc.subject.meshGangreneen_US
dc.subject.meshHumansen_US
dc.subject.meshIntestinal Perforation - Microbiology - Surgeryen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPostoperative Complicationsen_US
dc.subject.meshPremedicationen_US
dc.subject.meshSepsis - Microbiologyen_US
dc.titleThe bacteriology and septic complication of patients with appendicitisen_US
dc.typeArticleen_US
dc.identifier.emailFan, ST: stfan@hku.hken_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00000658-198411000-00003-
dc.identifier.pmid6486906-
dc.identifier.scopuseid_2-s2.0-0021747345en_US
dc.identifier.volume200en_US
dc.identifier.issue5en_US
dc.identifier.spage576en_US
dc.identifier.epage581en_US
dc.identifier.isiWOS:A1984TP47500003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLau, WY=7402933199en_US
dc.identifier.scopusauthoridTeohChan, CH=6603360891en_US
dc.identifier.scopusauthoridFan, ST=7402678224en_US

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