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Article: Evaluation of DNA mixtures from database search

TitleEvaluation of DNA mixtures from database search
Authors
KeywordsDatabase search
DNA
Likelihood ratio
Mixture
Issue Date2010
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BIOM
Citation
Biometrics, 2010, v. 66 n. 1, p. 233-238 How to Cite?
AbstractWith the aim of bridging the gap between DNA mixture analysis and DNA database search, a novel approach is proposed to evaluate the forensic evidence of DNA mixtures when the suspect is identified by the search of a database of DNA profiles. General formulae are developed for the calculation of the likelihood ratio for a two-person mixture under general situations including multiple matches and imperfect evidence. The influence of the prior probabilities on the weight of evidence under the scenario of multiple matches is demonstrated by a numerical example based on Hong Kong data. Our approach is shown to be capable of presenting the forensic evidence of DNA mixtures in a comprehensive way when the suspect is identified through database search. © 2009, The International Biometric Society.
Persistent Identifierhttp://hdl.handle.net/10722/172470
ISSN
2015 Impact Factor: 1.36
2015 SCImago Journal Rankings: 1.906
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChung, YKen_HK
dc.contributor.authorHu, YQen_HK
dc.contributor.authorFung, WKen_HK
dc.date.accessioned2012-10-30T06:22:41Z-
dc.date.available2012-10-30T06:22:41Z-
dc.date.issued2010en_HK
dc.identifier.citationBiometrics, 2010, v. 66 n. 1, p. 233-238en_HK
dc.identifier.issn0006-341Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/172470-
dc.description.abstractWith the aim of bridging the gap between DNA mixture analysis and DNA database search, a novel approach is proposed to evaluate the forensic evidence of DNA mixtures when the suspect is identified by the search of a database of DNA profiles. General formulae are developed for the calculation of the likelihood ratio for a two-person mixture under general situations including multiple matches and imperfect evidence. The influence of the prior probabilities on the weight of evidence under the scenario of multiple matches is demonstrated by a numerical example based on Hong Kong data. Our approach is shown to be capable of presenting the forensic evidence of DNA mixtures in a comprehensive way when the suspect is identified through database search. © 2009, The International Biometric Society.en_HK
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BIOMen_HK
dc.relation.ispartofBiometricsen_HK
dc.subjectDatabase searchen_HK
dc.subjectDNAen_HK
dc.subjectLikelihood ratioen_HK
dc.subjectMixtureen_HK
dc.subject.meshBase Sequenceen_US
dc.subject.meshDna - Geneticsen_US
dc.subject.meshDatabase Management Systemsen_US
dc.subject.meshDatabases, Geneticen_US
dc.subject.meshForensic Genetics - Methodsen_US
dc.subject.meshHumansen_US
dc.subject.meshInformation Storage And Retrieval - Methodsen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshSequence Alignment - Methodsen_US
dc.subject.meshSequence Analysis, Dna - Methodsen_US
dc.titleEvaluation of DNA mixtures from database searchen_HK
dc.typeArticleen_HK
dc.identifier.emailHu, YQ: yqhu@hku.hken_HK
dc.identifier.emailFung, WK: wingfung@hku.hken_HK
dc.identifier.authorityHu, YQ=rp00708en_HK
dc.identifier.authorityFung, WK=rp00696en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1541-0420.2009.01271.xen_HK
dc.identifier.pmid19459834-
dc.identifier.scopuseid_2-s2.0-77949747057en_HK
dc.identifier.hkuros171321-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77949747057&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume66en_HK
dc.identifier.issue1en_HK
dc.identifier.spage233en_HK
dc.identifier.epage238en_HK
dc.identifier.eissn1541-0420-
dc.identifier.isiWOS:000297280600004-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChung, YK=7404384597en_HK
dc.identifier.scopusauthoridHu, YQ=13410089000en_HK
dc.identifier.scopusauthoridFung, WK=13310399400en_HK

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