File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Human papillomavirus detection in self-collected vaginal specimens and matched clinician-collected cervical specimens

TitleHuman papillomavirus detection in self-collected vaginal specimens and matched clinician-collected cervical specimens
Authors
Issue Date2007
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ijgc.net/
Citation
International Journal Of Gynecological Cancer, 2007, v. 17 n. 3, p. 615-622 How to Cite?
AbstractHuman papillomavirus (HPV) detection is an integral part of cervical cancer screening, and a range of specimen collection procedures are being tested. Preliminary studies have found that the majority of women prefer self-collection of vaginal specimens instead of clinician-collected specimens of the cervix. The purposes of the current study were to explore the social and behavioral predictors of acceptance of self-collection of vaginal specimens among patients and to assess concordance in detection of HPV between clinician-collected cervical specimens and self-collected vaginal specimens. The study was conducted at a university family medicine clinic using a cross-sectional study design, and enrollment of women presenting for routine gynecological examination consecutively in a period of 1 year, self-administered questionnaires, collection of paired vaginal and cervical specimens for HPV DNA using Hybrid Capture 2, and cytologic analysis. Most women (79.8% [398/499]) agreed to collect vaginal specimens. In our study, 76.6% (216/282) African American women (AA), 88.1% (156/176) white non-Hispanic (WNH) women, and 63.4% (26/41) women of other races (P < 0.0001) agreed to self-collect vaginal specimens. HPV was detected in 16.0% (80/499) of clinician-collected cervical specimens and 26.1% (104/398) of self-collected vaginal specimens (P < 0.001). HPV detection was concordant in 13.4% (53/398) women in both cervical and vaginal specimens. Self-collection of vaginal specimens for HPV DNA detection is acceptable to most women presenting for routine gynecological examination. WNH women were more likely to obtain self-collected specimens than AA women. Vaginal specimens were more likely to be positive for HPV than were cervical specimens. © 2007, IGCS and ESGO.
Persistent Identifierhttp://hdl.handle.net/10722/172434
ISSN
2015 Impact Factor: 2.116
2015 SCImago Journal Rankings: 0.830
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKhanna, Nen_US
dc.contributor.authorMishra, SIen_US
dc.contributor.authorTian, Gen_US
dc.contributor.authorTan, MTen_US
dc.contributor.authorArnold, Sen_US
dc.contributor.authorLee, Cen_US
dc.contributor.authorRamachandran, Sen_US
dc.contributor.authorBell, Len_US
dc.contributor.authorBaquet, CRen_US
dc.contributor.authorLorincz, Aen_US
dc.date.accessioned2012-10-30T06:22:31Z-
dc.date.available2012-10-30T06:22:31Z-
dc.date.issued2007en_US
dc.identifier.citationInternational Journal Of Gynecological Cancer, 2007, v. 17 n. 3, p. 615-622en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/172434-
dc.description.abstractHuman papillomavirus (HPV) detection is an integral part of cervical cancer screening, and a range of specimen collection procedures are being tested. Preliminary studies have found that the majority of women prefer self-collection of vaginal specimens instead of clinician-collected specimens of the cervix. The purposes of the current study were to explore the social and behavioral predictors of acceptance of self-collection of vaginal specimens among patients and to assess concordance in detection of HPV between clinician-collected cervical specimens and self-collected vaginal specimens. The study was conducted at a university family medicine clinic using a cross-sectional study design, and enrollment of women presenting for routine gynecological examination consecutively in a period of 1 year, self-administered questionnaires, collection of paired vaginal and cervical specimens for HPV DNA using Hybrid Capture 2, and cytologic analysis. Most women (79.8% [398/499]) agreed to collect vaginal specimens. In our study, 76.6% (216/282) African American women (AA), 88.1% (156/176) white non-Hispanic (WNH) women, and 63.4% (26/41) women of other races (P < 0.0001) agreed to self-collect vaginal specimens. HPV was detected in 16.0% (80/499) of clinician-collected cervical specimens and 26.1% (104/398) of self-collected vaginal specimens (P < 0.001). HPV detection was concordant in 13.4% (53/398) women in both cervical and vaginal specimens. Self-collection of vaginal specimens for HPV DNA detection is acceptable to most women presenting for routine gynecological examination. WNH women were more likely to obtain self-collected specimens than AA women. Vaginal specimens were more likely to be positive for HPV than were cervical specimens. © 2007, IGCS and ESGO.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ijgc.net/en_US
dc.relation.ispartofInternational Journal of Gynecological Canceren_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAlphapapillomavirus - Genetics - Isolation & Purificationen_US
dc.subject.meshCervical Intraepithelial Neoplasia - Diagnosis - Virologyen_US
dc.subject.meshCervix Uteri - Pathology - Virologyen_US
dc.subject.meshDna Probes, Hpv - Analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMatched-Pair Analysisen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshModels, Biologicalen_US
dc.subject.meshPatient Acceptance Of Health Careen_US
dc.subject.meshSpecimen Handling - Methodsen_US
dc.subject.meshUterine Cervical Neoplasms - Diagnosis - Virologyen_US
dc.subject.meshVaginal Smears - Methodsen_US
dc.titleHuman papillomavirus detection in self-collected vaginal specimens and matched clinician-collected cervical specimensen_US
dc.typeArticleen_US
dc.identifier.emailTian, G: gltian@hku.hken_US
dc.identifier.authorityTian, G=rp00789en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1525-1438.2006.00835.xen_US
dc.identifier.pmid17504376-
dc.identifier.scopuseid_2-s2.0-34248331276en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34248331276&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume17en_US
dc.identifier.issue3en_US
dc.identifier.spage615en_US
dc.identifier.epage622en_US
dc.identifier.isiWOS:000246429600010-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridKhanna, N=7102045387en_US
dc.identifier.scopusauthoridMishra, SI=7402725393en_US
dc.identifier.scopusauthoridTian, G=25621549400en_US
dc.identifier.scopusauthoridTan, MT=7401464906en_US
dc.identifier.scopusauthoridArnold, S=16306625900en_US
dc.identifier.scopusauthoridLee, C=8366194200en_US
dc.identifier.scopusauthoridRamachandran, S=16307767600en_US
dc.identifier.scopusauthoridBell, L=8631251400en_US
dc.identifier.scopusauthoridBaquet, CR=6603799789en_US
dc.identifier.scopusauthoridLorincz, A=7102379837en_US
dc.identifier.citeulike1297689-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats