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Article: Characteristics and clinical correlates of prospective memory performance in first-episode schizophrenia

TitleCharacteristics and clinical correlates of prospective memory performance in first-episode schizophrenia
Authors
KeywordsCognitive functions
First-episode schizophrenia
Prospective memory
Issue Date2012
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
Schizophrenia Research, 2012, v. 135 n. 1-3, p. 34-39 How to Cite?
AbstractObjective: The aim of this study was to examine prospective memory (PM) and its socio-demographic, clinical, and neurocognitive correlates in first episode schizophrenia (FES). Methods: Fifty-one FES patients and 42 healthy controls formed the study sample. Time- and event-based PM (TBPM and EBPM) performance were measured with the Chinese version of the Cambridge Prospective Memory Test (C-CAMPROMPT). A battery of neuropsychological tests was also administered. Patients' clinical symptoms were evaluated with the Positive and Negative Symptom Scale (PANSS). Results: Patients performed significantly worse in both TBPM (8.7. ±. 5.3 vs. 14.8. ±. 3.5) and EBPM (11.3. ±. 4.7 vs. 15.7. ±. 2.7) than the controls. After controlling for age, gender, education level and neurocognitive test score, the difference in performance on the two types of PM tasks between patients and controls was no longer present. In multiple linear regression analyses, longer duration of untreated psychosis (DUP), lower scores of the Hopkins Verbal Learning Test-Revised (HVLT-R) and the categories completed of the Wisconsin Card Sorting Test (WCST-CC) and higher score of the Color Trails Test-2 (CTT-2) contributed to poorer TBPM performance, while lower score of HVLT-R, higher score of the perseverative errors of the Wisconsin Card Sorting Test (WCST-PE) and longer DUP contributed to worse performance on EBPM. Conclusions: Both subtypes of PM are impaired in first-episode schizophrenia suggesting that PM deficits are an integral part of the cognitive dysfunction in the disease process. © 2011 Elsevier B.V.
Persistent Identifierhttp://hdl.handle.net/10722/171980
ISSN
2021 Impact Factor: 4.662
2020 SCImago Journal Rankings: 1.923
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhou, FCen_US
dc.contributor.authorXiang, YTen_US
dc.contributor.authorWang, CYen_US
dc.contributor.authorDickerson, Fen_US
dc.contributor.authorAu, RWCen_US
dc.contributor.authorZhou, JJen_US
dc.contributor.authorZhou, Yen_US
dc.contributor.authorShum, DHKen_US
dc.contributor.authorChiu, HFKen_US
dc.contributor.authorMan, Den_US
dc.contributor.authorLee, EHMen_US
dc.contributor.authorYu, Xen_US
dc.contributor.authorChan, RCKen_US
dc.contributor.authorUngvari, GSen_US
dc.date.accessioned2012-10-30T06:19:10Z-
dc.date.available2012-10-30T06:19:10Z-
dc.date.issued2012en_US
dc.identifier.citationSchizophrenia Research, 2012, v. 135 n. 1-3, p. 34-39en_US
dc.identifier.issn0920-9964en_US
dc.identifier.urihttp://hdl.handle.net/10722/171980-
dc.description.abstractObjective: The aim of this study was to examine prospective memory (PM) and its socio-demographic, clinical, and neurocognitive correlates in first episode schizophrenia (FES). Methods: Fifty-one FES patients and 42 healthy controls formed the study sample. Time- and event-based PM (TBPM and EBPM) performance were measured with the Chinese version of the Cambridge Prospective Memory Test (C-CAMPROMPT). A battery of neuropsychological tests was also administered. Patients' clinical symptoms were evaluated with the Positive and Negative Symptom Scale (PANSS). Results: Patients performed significantly worse in both TBPM (8.7. ±. 5.3 vs. 14.8. ±. 3.5) and EBPM (11.3. ±. 4.7 vs. 15.7. ±. 2.7) than the controls. After controlling for age, gender, education level and neurocognitive test score, the difference in performance on the two types of PM tasks between patients and controls was no longer present. In multiple linear regression analyses, longer duration of untreated psychosis (DUP), lower scores of the Hopkins Verbal Learning Test-Revised (HVLT-R) and the categories completed of the Wisconsin Card Sorting Test (WCST-CC) and higher score of the Color Trails Test-2 (CTT-2) contributed to poorer TBPM performance, while lower score of HVLT-R, higher score of the perseverative errors of the Wisconsin Card Sorting Test (WCST-PE) and longer DUP contributed to worse performance on EBPM. Conclusions: Both subtypes of PM are impaired in first-episode schizophrenia suggesting that PM deficits are an integral part of the cognitive dysfunction in the disease process. © 2011 Elsevier B.V.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_US
dc.relation.ispartofSchizophrenia Researchen_US
dc.subjectCognitive functions-
dc.subjectFirst-episode schizophrenia-
dc.subjectProspective memory-
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMemory Disorders - Diagnosis - Etiologyen_US
dc.subject.meshMemory, Episodicen_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshSchizophrenia - Complicationsen_US
dc.subject.meshSchizophrenic Psychologyen_US
dc.subject.meshYoung Adulten_US
dc.titleCharacteristics and clinical correlates of prospective memory performance in first-episode schizophreniaen_US
dc.typeArticleen_US
dc.identifier.emailLee, EHM:edwinlhm@hku.hken_US
dc.identifier.authorityLee, EHM=rp01575en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.schres.2011.12.001en_US
dc.identifier.pmid22222379-
dc.identifier.scopuseid_2-s2.0-84857236017en_US
dc.identifier.hkuros206236-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84857236017&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume135en_US
dc.identifier.issue1-3en_US
dc.identifier.spage34en_US
dc.identifier.epage39en_US
dc.identifier.isiWOS:000300940000006-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridZhou, FC=54789365100en_US
dc.identifier.scopusauthoridXiang, YT=35241398400en_US
dc.identifier.scopusauthoridWang, CY=35345843000en_US
dc.identifier.scopusauthoridDickerson, F=7003825018en_US
dc.identifier.scopusauthoridAu, RWC=8512041800en_US
dc.identifier.scopusauthoridZhou, JJ=54879833900en_US
dc.identifier.scopusauthoridZhou, Y=54880136800en_US
dc.identifier.scopusauthoridShum, DHK=7004824442en_US
dc.identifier.scopusauthoridChiu, HFK=24447976700en_US
dc.identifier.scopusauthoridMan, D=7006360144en_US
dc.identifier.scopusauthoridLee, EHM=7406967099en_US
dc.identifier.scopusauthoridYu, X=35104208800en_US
dc.identifier.scopusauthoridChan, RCK=35725165500en_US
dc.identifier.scopusauthoridUngvari, GS=7006092063en_US
dc.identifier.citeulike10205139-
dc.identifier.issnl0920-9964-

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