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- Publisher Website: 10.1016/S0304-3940(98)01008-8
- Scopus: eid_2-s2.0-0033548229
- PMID: 10081941
- WOS: WOS:000078809900030
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Article: The effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary
Title | The effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary |
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Authors | |
Keywords | β-Endorphin Diabetes Pituitary Proopiomelanocortin mRNA Rat Streptozotocin |
Issue Date | 1999 |
Publisher | Elsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neulet |
Citation | Neuroscience Letters, 1999, v. 261 n. 1-2, p. 118-120 How to Cite? |
Abstract | Streptozotocin-induced diabetes for 4 weeks resulted in a decrease in proopiomelanocortin (POMC) mRNA in both the anterior lobe (AL) and the neuro- intermediate lobe (NIL) of the rat pituitary. The β-endorphin levels decreased in the NIL but not in the AL. It is concluded that the synthesis of POMC in the pituitary is inhibited in diabetic rats and that there is a decrease in β-endorphin release from the anterior pituitary. |
Persistent Identifier | http://hdl.handle.net/10722/171669 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.745 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cheung, CY | en_HK |
dc.contributor.author | Tang, F | en_HK |
dc.date.accessioned | 2012-10-30T06:16:15Z | - |
dc.date.available | 2012-10-30T06:16:15Z | - |
dc.date.issued | 1999 | en_HK |
dc.identifier.citation | Neuroscience Letters, 1999, v. 261 n. 1-2, p. 118-120 | en_HK |
dc.identifier.issn | 0304-3940 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/171669 | - |
dc.description.abstract | Streptozotocin-induced diabetes for 4 weeks resulted in a decrease in proopiomelanocortin (POMC) mRNA in both the anterior lobe (AL) and the neuro- intermediate lobe (NIL) of the rat pituitary. The β-endorphin levels decreased in the NIL but not in the AL. It is concluded that the synthesis of POMC in the pituitary is inhibited in diabetic rats and that there is a decrease in β-endorphin release from the anterior pituitary. | en_HK |
dc.language | eng | en_US |
dc.publisher | Elsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neulet | en_HK |
dc.relation.ispartof | Neuroscience Letters | en_HK |
dc.rights | Neuroscience Letters. Copyright © Elsevier Ireland Ltd. | - |
dc.subject | β-Endorphin | en_HK |
dc.subject | Diabetes | en_HK |
dc.subject | Pituitary | en_HK |
dc.subject | Proopiomelanocortin mRNA | en_HK |
dc.subject | Rat | en_HK |
dc.subject | Streptozotocin | en_HK |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Blood Glucose | en_US |
dc.subject.mesh | Diabetes Mellitus, Experimental - Genetics - Metabolism | en_US |
dc.subject.mesh | Gene Expression - Physiology | en_US |
dc.subject.mesh | Hypoglycemic Agents - Pharmacology | en_US |
dc.subject.mesh | Insulin - Pharmacology | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Pituitary Gland - Chemistry - Physiology | en_US |
dc.subject.mesh | Pro-Opiomelanocortin - Genetics | en_US |
dc.subject.mesh | Rna, Messenger - Analysis | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, Sprague-Dawley | en_US |
dc.subject.mesh | Beta-Endorphin - Metabolism | en_US |
dc.title | The effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Cheung, CY: chungey@hkucc.hku.hk | en_HK |
dc.identifier.email | Tang, F: ftang@hkucc.hku.hk | en_HK |
dc.identifier.authority | Cheung, CY=rp00404 | en_HK |
dc.identifier.authority | Tang, F=rp00327 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/S0304-3940(98)01008-8 | en_HK |
dc.identifier.pmid | 10081941 | - |
dc.identifier.scopus | eid_2-s2.0-0033548229 | en_HK |
dc.identifier.hkuros | 44135 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033548229&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 261 | en_HK |
dc.identifier.issue | 1-2 | en_HK |
dc.identifier.spage | 118 | en_HK |
dc.identifier.epage | 120 | en_HK |
dc.identifier.isi | WOS:000078809900030 | - |
dc.publisher.place | Ireland | en_HK |
dc.identifier.scopusauthorid | Cheung, CY=7202061836 | en_HK |
dc.identifier.scopusauthorid | Tang, F=7201979770 | en_HK |
dc.identifier.issnl | 0304-3940 | - |