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- Publisher Website: 10.1016/S0006-8993(96)00843-8
- Scopus: eid_2-s2.0-0030580423
- PMID: 8955954
- WOS: WOS:A1996VV25300037
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Article: Spontaneous activity of otolith-related vestibular nuclear neurons in the decerebrate rat
Title | Spontaneous activity of otolith-related vestibular nuclear neurons in the decerebrate rat |
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Authors | |
Keywords | bidirectional response sensitivity off-vertical rotation otolith rat spontaneous discharge vestibular nuclear neuron |
Issue Date | 1996 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainres |
Citation | Brain Research, 1996, v. 739 n. 1-2, p. 322-329 How to Cite? |
Abstract | The discharge properties of lateral and descending vestibular neurons responsive to constant velocity off-vertical axis rotations (OVAR) in the clockwise (CW) and counterclockwise (CCW) directions, were studied at the stationary and earth-horizontal position of decerebrate adult rats. From the coefficient of variation (CV), the spontaneous activities of OVAR-responsive neurons were classified into regular and irregular patterns. Of the neurons (n = 36) that showed symmetric and stable bidirectional response sensitivity (δ defined as CW gain over CCW gain) to OVAR (10° tilt), some exhibited progressive phase shift with velocity (1.75-15°/s) while others exhibited stable response phase. Most neurons of the former group (93% or 12/13) showed regular discharge pattern while only 22% (n = 5/23) of the latter group showed such a pattern. Though the phase-stable neurons showed a significantly higher average CV than the phase-shifted neurons, there was no significant difference between the mean spontaneous firing rates of these neurons. The neurons (n = 17) that showed asymmetric and variable δ to OVAR velocity can also be grouped - those that exhibited a greater gain with rotations directed towards the side of recording (I neurons) showed irregular discharge pattern while those that exhibited a greater gain with rotations directed towards the side contralateral to recording (C neurons) showed regular discharge pattern. The I and C neurons also exhibited significant difference in mean firing rates. The relationship between the response characteristics of the OVAR-responsive neurons and their spontaneous activity at the stationary and earth-horizontal position is discussed. |
Persistent Identifier | http://hdl.handle.net/10722/171634 |
ISSN | 2023 Impact Factor: 2.7 2023 SCImago Journal Rankings: 0.832 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lai, CH | en_US |
dc.contributor.author | Chan, YS | en_US |
dc.date.accessioned | 2012-10-30T06:16:04Z | - |
dc.date.available | 2012-10-30T06:16:04Z | - |
dc.date.issued | 1996 | en_US |
dc.identifier.citation | Brain Research, 1996, v. 739 n. 1-2, p. 322-329 | en_US |
dc.identifier.issn | 0006-8993 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/171634 | - |
dc.description.abstract | The discharge properties of lateral and descending vestibular neurons responsive to constant velocity off-vertical axis rotations (OVAR) in the clockwise (CW) and counterclockwise (CCW) directions, were studied at the stationary and earth-horizontal position of decerebrate adult rats. From the coefficient of variation (CV), the spontaneous activities of OVAR-responsive neurons were classified into regular and irregular patterns. Of the neurons (n = 36) that showed symmetric and stable bidirectional response sensitivity (δ defined as CW gain over CCW gain) to OVAR (10° tilt), some exhibited progressive phase shift with velocity (1.75-15°/s) while others exhibited stable response phase. Most neurons of the former group (93% or 12/13) showed regular discharge pattern while only 22% (n = 5/23) of the latter group showed such a pattern. Though the phase-stable neurons showed a significantly higher average CV than the phase-shifted neurons, there was no significant difference between the mean spontaneous firing rates of these neurons. The neurons (n = 17) that showed asymmetric and variable δ to OVAR velocity can also be grouped - those that exhibited a greater gain with rotations directed towards the side of recording (I neurons) showed irregular discharge pattern while those that exhibited a greater gain with rotations directed towards the side contralateral to recording (C neurons) showed regular discharge pattern. The I and C neurons also exhibited significant difference in mean firing rates. The relationship between the response characteristics of the OVAR-responsive neurons and their spontaneous activity at the stationary and earth-horizontal position is discussed. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainres | en_US |
dc.relation.ispartof | Brain Research | en_US |
dc.subject | bidirectional response sensitivity | - |
dc.subject | off-vertical rotation | - |
dc.subject | otolith | - |
dc.subject | rat | - |
dc.subject | spontaneous discharge | - |
dc.subject | vestibular nuclear neuron | - |
dc.subject.mesh | Action Potentials - Physiology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Decerebrate State | en_US |
dc.subject.mesh | Electric Stimulation | en_US |
dc.subject.mesh | Membrane Potentials - Physiology | en_US |
dc.subject.mesh | Neurons - Physiology | en_US |
dc.subject.mesh | Otolithic Membrane - Physiology | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, Sprague-Dawley | en_US |
dc.subject.mesh | Rotation | en_US |
dc.subject.mesh | Vestibular Nuclei - Cytology - Physiology | en_US |
dc.title | Spontaneous activity of otolith-related vestibular nuclear neurons in the decerebrate rat | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lai, CH:chlaib@hku.hk | en_US |
dc.identifier.email | Chan, YS:yschan@hkucc.hku.hk | en_US |
dc.identifier.authority | Lai, CH=rp00396 | en_US |
dc.identifier.authority | Chan, YS=rp00318 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/S0006-8993(96)00843-8 | en_US |
dc.identifier.pmid | 8955954 | - |
dc.identifier.scopus | eid_2-s2.0-0030580423 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0030580423&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 739 | en_US |
dc.identifier.issue | 1-2 | en_US |
dc.identifier.spage | 322 | en_US |
dc.identifier.epage | 329 | en_US |
dc.identifier.isi | WOS:A1996VV25300037 | - |
dc.publisher.place | Netherlands | en_US |
dc.identifier.scopusauthorid | Lai, CH=7403086597 | en_US |
dc.identifier.scopusauthorid | Chan, YS=7403676627 | en_US |
dc.identifier.issnl | 0006-8993 | - |