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Article: Effect of N-acetylserotonin on the serum level of thyroid-stimulating hormone in the male rat

TitleEffect of N-acetylserotonin on the serum level of thyroid-stimulating hormone in the male rat
Authors
Issue Date1983
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/NEN
Citation
Neuroendocrinology, 1983, v. 36 n. 4, p. 268-271 How to Cite?
AbstractThe effect of N-acetylserotonin (NAS) on serum levels of thyroid-stimulating hormone (TSH) in the male rat was investigated. In the first experiment, NAS and carrier were injected intraperitoneally into rats. The animals were sacrificed 30 and 60 min after injection. It was found that NAS (100 μg/rat) significantly depressed serum TSH 60 min after injection when compared with saline-injected controls. In another experiment in which samples were obtained from rats at 0, 30, 60, 90 and 120 min after injection, significant decrease in serum TSH was observed at all time intervals after NAS (100 μg/rat) injection while no such difference was observed in the saline-injected group. It is suggested that NAS may exert an inhibitory effect on TSH secretion.
Persistent Identifierhttp://hdl.handle.net/10722/171479
ISSN
2015 Impact Factor: 2.583
2015 SCImago Journal Rankings: 1.479
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTang, Fen_US
dc.contributor.authorPang, SFen_US
dc.date.accessioned2012-10-30T06:15:22Z-
dc.date.available2012-10-30T06:15:22Z-
dc.date.issued1983en_US
dc.identifier.citationNeuroendocrinology, 1983, v. 36 n. 4, p. 268-271en_US
dc.identifier.issn0028-3835en_US
dc.identifier.urihttp://hdl.handle.net/10722/171479-
dc.description.abstractThe effect of N-acetylserotonin (NAS) on serum levels of thyroid-stimulating hormone (TSH) in the male rat was investigated. In the first experiment, NAS and carrier were injected intraperitoneally into rats. The animals were sacrificed 30 and 60 min after injection. It was found that NAS (100 μg/rat) significantly depressed serum TSH 60 min after injection when compared with saline-injected controls. In another experiment in which samples were obtained from rats at 0, 30, 60, 90 and 120 min after injection, significant decrease in serum TSH was observed at all time intervals after NAS (100 μg/rat) injection while no such difference was observed in the saline-injected group. It is suggested that NAS may exert an inhibitory effect on TSH secretion.en_US
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/NENen_US
dc.relation.ispartofNeuroendocrinologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshMaleen_US
dc.subject.meshMelatonin - Biosynthesis - Physiologyen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.subject.meshSerotonin - Analogs & Derivatives - Metabolism - Pharmacologyen_US
dc.subject.meshThyrotropin - Blooden_US
dc.titleEffect of N-acetylserotonin on the serum level of thyroid-stimulating hormone in the male raten_US
dc.typeArticleen_US
dc.identifier.emailTang, F:ftang@hkucc.hku.hken_US
dc.identifier.authorityTang, F=rp00327en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1159/000123466-
dc.identifier.pmid6866213-
dc.identifier.scopuseid_2-s2.0-0020537380en_US
dc.identifier.volume36en_US
dc.identifier.issue4en_US
dc.identifier.spage268en_US
dc.identifier.epage271en_US
dc.identifier.isiWOS:A1983QF84700004-
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridTang, F=7201979770en_US
dc.identifier.scopusauthoridPang, SF=7402528719en_US

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