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Article: Retrospective study of vigabatrin and psychiatric behavioural disturbances

TitleRetrospective study of vigabatrin and psychiatric behavioural disturbances
Authors
Issue Date1995
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyres
Citation
Epilepsy Research, 1995, v. 21 n. 3, p. 227-230 How to Cite?
AbstractVigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring.
Persistent Identifierhttp://hdl.handle.net/10722/171169
ISSN
2015 Impact Factor: 2.237
2015 SCImago Journal Rankings: 1.026
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, ICKen_US
dc.date.accessioned2012-10-30T06:12:30Z-
dc.date.available2012-10-30T06:12:30Z-
dc.date.issued1995en_US
dc.identifier.citationEpilepsy Research, 1995, v. 21 n. 3, p. 227-230en_US
dc.identifier.issn0920-1211en_US
dc.identifier.urihttp://hdl.handle.net/10722/171169-
dc.description.abstractVigabatrin (VGB) is an effective add-on anti-epileptic drug. The major serious adverse drug reactions (ADRs) are behavioural and psychiatric disturbances. This study does not support the view that a previous history of behavioural and psychiatric features increases the risk of behavioural/psychiatric ADRs (relative risk 1.23, 95% CI 0.57-2.66, P = 0.61). The results suggest that a low starting does of vigabatrin does not reduce the risk of psychiatric and behavioural ADRs (P = 0.31) or prevent a more overt psychotic reaction from occurring.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/epilepsyresen_US
dc.relation.ispartofEpilepsy Researchen_US
dc.titleRetrospective study of vigabatrin and psychiatric behavioural disturbancesen_US
dc.typeArticleen_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0920-1211(95)00022-3en_US
dc.identifier.pmid8536676-
dc.identifier.scopuseid_2-s2.0-0029094094en_US
dc.identifier.volume21en_US
dc.identifier.issue3en_US
dc.identifier.spage227en_US
dc.identifier.epage230en_US
dc.identifier.isiWOS:A1995RV90000006-
dc.publisher.placeNetherlandsen_US

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