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Article: Endothelial cell signaling and endothelial dysfunction

TitleEndothelial cell signaling and endothelial dysfunction
Authors
Issue Date1995
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjhyper
Citation
American Journal Of Hypertension, 1995, v. 8 n. 5 II SUPPL., p. 28S-41S How to Cite?
AbstractEndothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some, of the extracellular signaling mechanisms employed by normal endothelial cells to exert a protective influence in the vascular wall and those signals generated by dysfunctional cells to promote the atherosclerotic process. It will also discuss the intracellular processes that regulate the release/expression of these signals and that control the transformation of this protective cell to one that promotes the development of vascular disease.
Persistent Identifierhttp://hdl.handle.net/10722/171166
ISSN
2015 Impact Factor: 3.182
2015 SCImago Journal Rankings: 1.397
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorFlavahan, NAen_US
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:12:29Z-
dc.date.available2012-10-30T06:12:29Z-
dc.date.issued1995en_US
dc.identifier.citationAmerican Journal Of Hypertension, 1995, v. 8 n. 5 II SUPPL., p. 28S-41Sen_US
dc.identifier.issn0895-7061en_US
dc.identifier.urihttp://hdl.handle.net/10722/171166-
dc.description.abstractEndothelial cells have an important protective role in maintaining the normal physiologic function of the vascular wall. When these cells become dysfunctional, they lose this protective influence and they actively promote pathophysiological changes within the blood vessel. This review will discuss some, of the extracellular signaling mechanisms employed by normal endothelial cells to exert a protective influence in the vascular wall and those signals generated by dysfunctional cells to promote the atherosclerotic process. It will also discuss the intracellular processes that regulate the release/expression of these signals and that control the transformation of this protective cell to one that promotes the development of vascular disease.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjhyperen_US
dc.relation.ispartofAmerican Journal of Hypertensionen_US
dc.subject.meshAnimalsen_US
dc.subject.meshEndothelium, Vascular - Physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMuscle Contractionen_US
dc.subject.meshMuscle, Smooth, Vascular - Physiologyen_US
dc.subject.meshSignal Transduction - Physiologyen_US
dc.subject.meshVascular Diseases - Physiopathologyen_US
dc.titleEndothelial cell signaling and endothelial dysfunctionen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0895-7061(95)00030-S-
dc.identifier.pmid7646842-
dc.identifier.scopuseid_2-s2.0-0029057222en_US
dc.identifier.volume8en_US
dc.identifier.issue5 II SUPPL.en_US
dc.identifier.spage28Sen_US
dc.identifier.epage41Sen_US
dc.identifier.isiWOS:A1995RB67900005-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridFlavahan, NA=7006398882en_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US

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