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Article: Endothelium-derived relaxing factor and coronary vasospasm

TitleEndothelium-derived relaxing factor and coronary vasospasm
Authors
Issue Date1989
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://circ.ahajournals.org
Citation
Circulation, 1989, v. 80 n. 1, p. 1-9 How to Cite?
AbstractThe endothelium releases the powerful vasodilator and antiaggregatory substance, EDRF, both under basal conditions and upon stimulation by a wide variety of agents. Endothelial injury or dysfunction may play an important role in the spasmogenicity of the coronary artery, although other possible alterations related to atherosclerosis should also be considered. Among the possible stimuli, aggregating platelets are important as a source of vasoconstrictor substances. The endothelium may also produce the vasoactive substances EDHF and EDCF(s). Their pathophysiologic significance remains to be determined.
Persistent Identifierhttp://hdl.handle.net/10722/170916
ISSN
2015 Impact Factor: 17.047
2015 SCImago Journal Rankings: 7.853
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorVanhoutte, PMen_US
dc.contributor.authorShimokawa, Hen_US
dc.date.accessioned2012-10-30T06:11:25Z-
dc.date.available2012-10-30T06:11:25Z-
dc.date.issued1989en_US
dc.identifier.citationCirculation, 1989, v. 80 n. 1, p. 1-9en_US
dc.identifier.issn0009-7322en_US
dc.identifier.urihttp://hdl.handle.net/10722/170916-
dc.description.abstractThe endothelium releases the powerful vasodilator and antiaggregatory substance, EDRF, both under basal conditions and upon stimulation by a wide variety of agents. Endothelial injury or dysfunction may play an important role in the spasmogenicity of the coronary artery, although other possible alterations related to atherosclerosis should also be considered. Among the possible stimuli, aggregating platelets are important as a source of vasoconstrictor substances. The endothelium may also produce the vasoactive substances EDHF and EDCF(s). Their pathophysiologic significance remains to be determined.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://circ.ahajournals.orgen_US
dc.relation.ispartofCirculationen_US
dc.subject.meshAnimalsen_US
dc.subject.meshArteriosclerosis - Metabolism - Physiopathologyen_US
dc.subject.meshBiological Factors - Metabolism - Physiologyen_US
dc.subject.meshBlood Platelets - Physiologyen_US
dc.subject.meshCoronary Vasospasm - Metabolismen_US
dc.subject.meshEndothelium, Vascular - Metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshNitric Oxideen_US
dc.subject.meshVasoconstrictionen_US
dc.titleEndothelium-derived relaxing factor and coronary vasospasmen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1161/01.CIR.80.1.1-
dc.identifier.pmid2661051-
dc.identifier.scopuseid_2-s2.0-0024312198en_US
dc.identifier.volume80en_US
dc.identifier.issue1en_US
dc.identifier.spage1en_US
dc.identifier.epage9en_US
dc.identifier.isiWOS:A1989AE26700001-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.scopusauthoridShimokawa, H=16684837100en_US

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