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Article: Lysophosphatidylcholine accumulation in the ischemic canine heart

TitleLysophosphatidylcholine accumulation in the ischemic canine heart
Authors
Issue Date1988
PublisherA O C S Press. The Journal's web site is located at http://www.aocs.org/press/lipids.htm
Citation
Lipids, 1988, v. 23 n. 1, p. 32-35 How to Cite?
AbstractThe production of cardiac arrhythmias and the elevation of lysophosphatidylcholine level in the ischemic myocardium have been well-documented in a number of studies. However, the relationship between the production arrhythmias and the elevation of tissue lysophosphatidylcholine level was not reported. In this study, the lysophosphatidylcholine level and the occurrence of cardiac arrhythmias in the ischemic canine heart were monitored. A temporal relationship between the accumulation of lysophosphatidylcholine and the occurrence of arrhythmias was established after five hr of ischemia. A significant elevation of lysophosphatidylcholine was detected at three hr of ischemia without the occurrence of arrhythmias. The results indicate that cardiac arrhythmias did not cause the elevation of lysophosphatidylcholine and if lysophospholipids are causally related to the arrhythmias that a critical level of the lysophospholipid must accumulate in order to elicit electrophysiological alterations. © 1988 American Oil Chemists' Society.
Persistent Identifierhttp://hdl.handle.net/10722/170870
ISSN
2015 Impact Factor: 1.892
2015 SCImago Journal Rankings: 0.795
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKinnaird, AAAen_US
dc.contributor.authorChoy, PCen_US
dc.contributor.authorMan, RYKen_US
dc.date.accessioned2012-10-30T06:11:11Z-
dc.date.available2012-10-30T06:11:11Z-
dc.date.issued1988en_US
dc.identifier.citationLipids, 1988, v. 23 n. 1, p. 32-35en_US
dc.identifier.issn0024-4201en_US
dc.identifier.urihttp://hdl.handle.net/10722/170870-
dc.description.abstractThe production of cardiac arrhythmias and the elevation of lysophosphatidylcholine level in the ischemic myocardium have been well-documented in a number of studies. However, the relationship between the production arrhythmias and the elevation of tissue lysophosphatidylcholine level was not reported. In this study, the lysophosphatidylcholine level and the occurrence of cardiac arrhythmias in the ischemic canine heart were monitored. A temporal relationship between the accumulation of lysophosphatidylcholine and the occurrence of arrhythmias was established after five hr of ischemia. A significant elevation of lysophosphatidylcholine was detected at three hr of ischemia without the occurrence of arrhythmias. The results indicate that cardiac arrhythmias did not cause the elevation of lysophosphatidylcholine and if lysophospholipids are causally related to the arrhythmias that a critical level of the lysophospholipid must accumulate in order to elicit electrophysiological alterations. © 1988 American Oil Chemists' Society.en_US
dc.languageengen_US
dc.publisherA O C S Press. The Journal's web site is located at http://www.aocs.org/press/lipids.htmen_US
dc.relation.ispartofLipidsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBody Water - Metabolismen_US
dc.subject.meshCholesterol - Metabolismen_US
dc.subject.meshCoronary Disease - Metabolismen_US
dc.subject.meshDogsen_US
dc.subject.meshFemaleen_US
dc.subject.meshKineticsen_US
dc.subject.meshLysophosphatidylcholines - Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMyocardium - Metabolismen_US
dc.subject.meshPhospholipids - Metabolismen_US
dc.subject.meshReference Valuesen_US
dc.titleLysophosphatidylcholine accumulation in the ischemic canine hearten_US
dc.typeArticleen_US
dc.identifier.emailMan, RYK:rykman@hkucc.hku.hken_US
dc.identifier.authorityMan, RYK=rp00236en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/BF02535301en_US
dc.identifier.pmid3352470-
dc.identifier.scopuseid_2-s2.0-0023716905en_US
dc.identifier.volume23en_US
dc.identifier.issue1en_US
dc.identifier.spage32en_US
dc.identifier.epage35en_US
dc.identifier.isiWOS:A1988L982600005-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridKinnaird, AAA=6603472891en_US
dc.identifier.scopusauthoridChoy, PC=7006633002en_US
dc.identifier.scopusauthoridMan, RYK=7004986435en_US

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