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Article: Non-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteries

TitleNon-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteries
Authors
Issue Date1982
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ejphar
Citation
European Journal Of Pharmacology, 1982, v. 80 n. 2-3, p. 251-254 How to Cite?
AbstractElectrical stimulation caused frequency-dependent reversible relaxations of canine coronary arteries made to contract with prostaglandin F(2α), phenylephrine, 5-hydroxytryptamine, potassium chloride, or angiotensin II. These contractions were not affected by cold storage, tetrodotoxin, α- and β-adrenergic blockade and atropine, demonstrating that they probably are not due to activation of inhibitory nerves. The relaxation persisted in the presence of indomethacin and after removal of the endothelium. They were not seen in splenic arteries and saphenous veins, demonstrating the high sensitivity of the coronary blood vessel wall to the inhibitory effects of the electric impulses.
Persistent Identifierhttp://hdl.handle.net/10722/170677
ISSN
2015 Impact Factor: 2.73
2015 SCImago Journal Rankings: 1.115
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorRooke, Ten_US
dc.contributor.authorCohen, RAen_US
dc.contributor.authorVerbeuren, TJen_US
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:10:24Z-
dc.date.available2012-10-30T06:10:24Z-
dc.date.issued1982en_US
dc.identifier.citationEuropean Journal Of Pharmacology, 1982, v. 80 n. 2-3, p. 251-254en_US
dc.identifier.issn0014-2999en_US
dc.identifier.urihttp://hdl.handle.net/10722/170677-
dc.description.abstractElectrical stimulation caused frequency-dependent reversible relaxations of canine coronary arteries made to contract with prostaglandin F(2α), phenylephrine, 5-hydroxytryptamine, potassium chloride, or angiotensin II. These contractions were not affected by cold storage, tetrodotoxin, α- and β-adrenergic blockade and atropine, demonstrating that they probably are not due to activation of inhibitory nerves. The relaxation persisted in the presence of indomethacin and after removal of the endothelium. They were not seen in splenic arteries and saphenous veins, demonstrating the high sensitivity of the coronary blood vessel wall to the inhibitory effects of the electric impulses.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/ejpharen_US
dc.relation.ispartofEuropean Journal of Pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCoronary Vessels - Drug Effects - Innervation - Physiologyen_US
dc.subject.meshDogsen_US
dc.subject.meshElectric Stimulationen_US
dc.titleNon-neurogenic inhibitory effect of electrical impulses in isolated canine coronary arteriesen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0014-2999(82)90063-2-
dc.identifier.pmid7106182-
dc.identifier.scopuseid_2-s2.0-0020054023en_US
dc.identifier.volume80en_US
dc.identifier.issue2-3en_US
dc.identifier.spage251en_US
dc.identifier.epage254en_US
dc.identifier.isiWOS:A1982NS87400014-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridRooke, T=8757981200en_US
dc.identifier.scopusauthoridCohen, RA=35562815800en_US
dc.identifier.scopusauthoridVerbeuren, TJ=7007006534en_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US

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