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Article: Pharmacology of the blood vessel wall

TitlePharmacology of the blood vessel wall
Authors
Issue Date1981
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/
Citation
Journal Of Cardiovascular Pharmacology, 1981, v. 3 n. 6, p. 1359-1369 How to Cite?
AbstractChanges in the degree of contraction of the smooth muscle cells of the blood vessel wall permit the control of vascular function at the different levels of the circulation. In the aorta and the large arteries, they adjust the stiffness of the arterial wall and, together with changes in peripheral resistance, modulate the impedance of the vascular circuit. At the level of the small arteries and the arterioles, active changes in vascular diameter regulate the blood flow to the individual tissues and, by altering the total peripheral resistance, also help determine the arterial pressure. Active dilation and constriction of the systemic veins, in particular those of the splanchnic area, adjust the total capacity of the cardiovascular system and thus control the return of blood to the right heart; active changes in the diameter of the cutaneous veins are a major determinant of the thermoregulatory function of the skin circulation. This overview briefly discusses the signals that alter the degree of contraction of the vascular smooth muscle cells.
Persistent Identifierhttp://hdl.handle.net/10722/170659
ISSN
2015 Impact Factor: 2.462
2015 SCImago Journal Rankings: 0.962
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:10:19Z-
dc.date.available2012-10-30T06:10:19Z-
dc.date.issued1981en_US
dc.identifier.citationJournal Of Cardiovascular Pharmacology, 1981, v. 3 n. 6, p. 1359-1369en_US
dc.identifier.issn0160-2446en_US
dc.identifier.urihttp://hdl.handle.net/10722/170659-
dc.description.abstractChanges in the degree of contraction of the smooth muscle cells of the blood vessel wall permit the control of vascular function at the different levels of the circulation. In the aorta and the large arteries, they adjust the stiffness of the arterial wall and, together with changes in peripheral resistance, modulate the impedance of the vascular circuit. At the level of the small arteries and the arterioles, active changes in vascular diameter regulate the blood flow to the individual tissues and, by altering the total peripheral resistance, also help determine the arterial pressure. Active dilation and constriction of the systemic veins, in particular those of the splanchnic area, adjust the total capacity of the cardiovascular system and thus control the return of blood to the right heart; active changes in the diameter of the cutaneous veins are a major determinant of the thermoregulatory function of the skin circulation. This overview briefly discusses the signals that alter the degree of contraction of the vascular smooth muscle cells.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/en_US
dc.relation.ispartofJournal of Cardiovascular Pharmacologyen_US
dc.subject.meshAngiotensin Ii - Physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAutonomic Nervous System - Physiologyen_US
dc.subject.meshBlood Vessels - Drug Effects - Innervation - Physiologyen_US
dc.subject.meshCatecholamines - Physiologyen_US
dc.subject.meshEndothelium - Physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMuscle, Smooth, Vascular - Drug Effectsen_US
dc.subject.meshReceptors, Adrenergic, Alpha - Physiologyen_US
dc.subject.meshSerotonin - Physiologyen_US
dc.titlePharmacology of the blood vessel wallen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00005344-198111000-00023-
dc.identifier.pmid6173536-
dc.identifier.scopuseid_2-s2.0-0019837916en_US
dc.identifier.volume3en_US
dc.identifier.issue6en_US
dc.identifier.spage1359en_US
dc.identifier.epage1369en_US
dc.identifier.isiWOS:A1981MQ33500023-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US

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