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Article: Acetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dog

TitleAcetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dog
Authors
Issue Date1976
Citation
Archives Internationales De Pharmacodynamie Et De Therapie, 1976, v. 221 n. 2, p. 347-350 How to Cite?
AbstractThe present experiments were designed to investigate whether acetylcholine affects the responsiveness of blood vessels to K+. Helical strips of saphenous veins and of pulmonary and tibial arteries, and longitudinal strips of mesenteric veins were studied in an organ chamber at 37°C; changes in isometric tension were recorded. The present experiments indicate that acetylcholine inhibits the release of adrenergic neurotransmitter caused by depolarization of the nerve endings in different blood vessel preparations, as it does during nerve stimulation.
Persistent Identifierhttp://hdl.handle.net/10722/170511
ISSN
1998 Impact Factor: 0.72
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorVerbeuren, TJen_US
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:09:45Z-
dc.date.available2012-10-30T06:09:45Z-
dc.date.issued1976en_US
dc.identifier.citationArchives Internationales De Pharmacodynamie Et De Therapie, 1976, v. 221 n. 2, p. 347-350en_US
dc.identifier.issn0003-9780en_US
dc.identifier.urihttp://hdl.handle.net/10722/170511-
dc.description.abstractThe present experiments were designed to investigate whether acetylcholine affects the responsiveness of blood vessels to K+. Helical strips of saphenous veins and of pulmonary and tibial arteries, and longitudinal strips of mesenteric veins were studied in an organ chamber at 37°C; changes in isometric tension were recorded. The present experiments indicate that acetylcholine inhibits the release of adrenergic neurotransmitter caused by depolarization of the nerve endings in different blood vessel preparations, as it does during nerve stimulation.en_US
dc.languageengen_US
dc.relation.ispartofArchives Internationales de Pharmacodynamie et de Therapieen_US
dc.subject.meshAcetylcholine - Pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlood Vessels - Drug Effects - Metabolismen_US
dc.subject.meshDepression, Chemicalen_US
dc.subject.meshDogsen_US
dc.subject.meshMesenteric Veins - Metabolismen_US
dc.subject.meshNorepinephrine - Antagonists & Inhibitors - Metabolismen_US
dc.subject.meshPotassium - Pharmacologyen_US
dc.subject.meshPulmonary Artery - Drug Effectsen_US
dc.subject.meshRegional Blood Flow - Drug Effectsen_US
dc.subject.meshSaphenous Vein - Drug Effectsen_US
dc.subject.meshTibia - Blood Supplyen_US
dc.titleAcetylcholine inhibits potassium evoked release of 3H norepinephrine in different blood vessels of the dogen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid962442-
dc.identifier.scopuseid_2-s2.0-0017063260en_US
dc.identifier.volume221en_US
dc.identifier.issue2en_US
dc.identifier.spage347en_US
dc.identifier.epage350en_US
dc.identifier.isiWOS:A1976BV68400020-
dc.identifier.scopusauthoridVerbeuren, TJ=7007006534en_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US

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