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Article: Registry- and clinic-based analyses of birth defects and syndromes associated with cleft lip/palate in Victoria, Australia

TitleRegistry- and clinic-based analyses of birth defects and syndromes associated with cleft lip/palate in Victoria, Australia
Authors
Issue Date2009
PublisherAllen Press Inc. The Journal's web site is located at http://cpcj.allenpress.com
Citation
Cleft Palate-Craniofacial Journal, 2009, v. 46 n. 6, p. 583-587 How to Cite?
AbstractObjective: To study the birth defects and syndromes associated with cleft lip and/or cleft palate in children born from 2000 through 2002 in Victoria, Australia, comparing data from the birth defects registry and detailed clinical assessment. Design, Setting, and Participants: Data recorded in the Victorian Birth Defects Register were retrieved for all children with cleft lip and/or palate born from 2000 through 2002. In parallel, a cohort of children with clefts was recruited from the two cleft centers in Victoria. Clinical data were collected using structured parental interview, clinical/dysmorphologic examination, and file review. Results: Victorian Birth Defects Register records of 312 children with cleft lip and/or palate were identified, and 53 children were recruited for the clinical study. The clinical study found a higher proportion of nonisolated clefts than were listed in the registry; this was largely due to the more detailed assessment, but some selection bias was possible. Poor growth and developmental delay were most likely to predict the presence of other birth defects or a syndrome diagnosis in a child with cleft lip and/or palate. The clinical study led to modifications to 16/53 (30.2%) of records in the Victorian Birth Defects Register. Conclusions: This study provides complementary registry- and clinic-based data on cleft lip and/or palate-associated malformations and syndrome diagnoses in Australian children and emphasizes the value of having a clinician experienced in dysmorphology involved in cleft services with ongoing reporting to the Victorian Birth Defects Register.
Persistent Identifierhttp://hdl.handle.net/10722/170425
ISSN
2010 Impact Factor: 0.77
2015 SCImago Journal Rankings: 0.685
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTan, TYen_US
dc.contributor.authorAmor, DJen_US
dc.contributor.authorRiley, Men_US
dc.contributor.authorHalliday, Jen_US
dc.contributor.authorKilpatrick, Nen_US
dc.contributor.authorSimms, Ken_US
dc.contributor.authorWhite, SMen_US
dc.date.accessioned2012-10-30T06:08:27Z-
dc.date.available2012-10-30T06:08:27Z-
dc.date.issued2009en_US
dc.identifier.citationCleft Palate-Craniofacial Journal, 2009, v. 46 n. 6, p. 583-587en_US
dc.identifier.issn1055-6656en_US
dc.identifier.urihttp://hdl.handle.net/10722/170425-
dc.description.abstractObjective: To study the birth defects and syndromes associated with cleft lip and/or cleft palate in children born from 2000 through 2002 in Victoria, Australia, comparing data from the birth defects registry and detailed clinical assessment. Design, Setting, and Participants: Data recorded in the Victorian Birth Defects Register were retrieved for all children with cleft lip and/or palate born from 2000 through 2002. In parallel, a cohort of children with clefts was recruited from the two cleft centers in Victoria. Clinical data were collected using structured parental interview, clinical/dysmorphologic examination, and file review. Results: Victorian Birth Defects Register records of 312 children with cleft lip and/or palate were identified, and 53 children were recruited for the clinical study. The clinical study found a higher proportion of nonisolated clefts than were listed in the registry; this was largely due to the more detailed assessment, but some selection bias was possible. Poor growth and developmental delay were most likely to predict the presence of other birth defects or a syndrome diagnosis in a child with cleft lip and/or palate. The clinical study led to modifications to 16/53 (30.2%) of records in the Victorian Birth Defects Register. Conclusions: This study provides complementary registry- and clinic-based data on cleft lip and/or palate-associated malformations and syndrome diagnoses in Australian children and emphasizes the value of having a clinician experienced in dysmorphology involved in cleft services with ongoing reporting to the Victorian Birth Defects Register.en_US
dc.languageengen_US
dc.publisherAllen Press Inc. The Journal's web site is located at http://cpcj.allenpress.comen_US
dc.relation.ispartofCleft Palate-Craniofacial Journalen_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshCleft Lip - Epidemiologyen_US
dc.subject.meshCleft Palate - Epidemiologyen_US
dc.subject.meshCongenital Abnormalities - Epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInterviews As Topicen_US
dc.subject.meshMaleen_US
dc.subject.meshRegistriesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSyndromeen_US
dc.subject.meshVictoria - Epidemiologyen_US
dc.titleRegistry- and clinic-based analyses of birth defects and syndromes associated with cleft lip/palate in Victoria, Australiaen_US
dc.typeArticleen_US
dc.identifier.emailTan, TY:tanty@hku.hken_US
dc.identifier.authorityTan, TY=rp01380en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1597/07-241.1en_US
dc.identifier.pmid19929084-
dc.identifier.scopuseid_2-s2.0-70849105915en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70849105915&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume46en_US
dc.identifier.issue6en_US
dc.identifier.spage583en_US
dc.identifier.epage587en_US
dc.identifier.isiWOS:000271992500003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridTan, TY=8567188100en_US
dc.identifier.scopusauthoridAmor, DJ=7004097069en_US
dc.identifier.scopusauthoridRiley, M=7203009777en_US
dc.identifier.scopusauthoridHalliday, J=7103245049en_US
dc.identifier.scopusauthoridKilpatrick, N=35571251500en_US
dc.identifier.scopusauthoridSimms, K=36879211400en_US
dc.identifier.scopusauthoridWhite, SM=35480530300en_US

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