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Article: Update on perinatally acquired human immunodeficiency virus infection in children followed at one centre in Hong Kong

TitleUpdate on perinatally acquired human immunodeficiency virus infection in children followed at one centre in Hong Kong
Authors
KeywordsPerinatal Human Immunodeficiency Virus Infection
Issue Date2006
PublisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
Citation
Hong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 215-222+265 How to Cite?
AbstractTo date, 17 children with perinatally-acquired human immunodeficiency virus (HIV) infection have been diagnosed and reported in Hong Kong. We reported on our experience at Queen Mary Hospital with 8 of the 11 children diagnosed in 2000. Since then, 4 more children have been referred to us. This study reports on these new patients as well as provides an update on the existing patients from May 2000 to May 2006. Two of the four new patients had AIDS at the time of diagnosis. All patients were given highly active antiretroviral therapy. Over 80% of the infected children had long-term undetectable HIV viral load after initiation of treatment, the longest duration being 7 years to date. Changes in management as a result of immune reconstitution in these children included the discontinuation of monthly IVIG infusion in some children and the discontinuation of primary prophylaxis against Pneumocystis jirovecii pneumonia, formerly Pneumocystis carinii pneumonia (PCP). Disclosure was an important issue as the children were growing older. With the exception of one 4 years old boy who was too young, full disclosure was achieved in half of the patients with a mean age of 8.9 years. As these medically well children enter adolescence, additional services including support with disclosure to others, self acceptance, therapy and sexual health would be needed.
Persistent Identifierhttp://hdl.handle.net/10722/170371
ISSN
2015 Impact Factor: 0.194
2015 SCImago Journal Rankings: 0.123
References

 

DC FieldValueLanguage
dc.contributor.authorChiu, SSen_US
dc.contributor.authorLau, YLen_US
dc.date.accessioned2012-10-30T06:07:51Z-
dc.date.available2012-10-30T06:07:51Z-
dc.date.issued2006en_US
dc.identifier.citationHong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 215-222+265en_US
dc.identifier.issn1013-9923en_US
dc.identifier.urihttp://hdl.handle.net/10722/170371-
dc.description.abstractTo date, 17 children with perinatally-acquired human immunodeficiency virus (HIV) infection have been diagnosed and reported in Hong Kong. We reported on our experience at Queen Mary Hospital with 8 of the 11 children diagnosed in 2000. Since then, 4 more children have been referred to us. This study reports on these new patients as well as provides an update on the existing patients from May 2000 to May 2006. Two of the four new patients had AIDS at the time of diagnosis. All patients were given highly active antiretroviral therapy. Over 80% of the infected children had long-term undetectable HIV viral load after initiation of treatment, the longest duration being 7 years to date. Changes in management as a result of immune reconstitution in these children included the discontinuation of monthly IVIG infusion in some children and the discontinuation of primary prophylaxis against Pneumocystis jirovecii pneumonia, formerly Pneumocystis carinii pneumonia (PCP). Disclosure was an important issue as the children were growing older. With the exception of one 4 years old boy who was too young, full disclosure was achieved in half of the patients with a mean age of 8.9 years. As these medically well children enter adolescence, additional services including support with disclosure to others, self acceptance, therapy and sexual health would be needed.en_US
dc.languageengen_US
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.aspen_US
dc.relation.ispartofHong Kong Journal of Paediatricsen_US
dc.subjectPerinatal Human Immunodeficiency Virus Infectionen_US
dc.titleUpdate on perinatally acquired human immunodeficiency virus infection in children followed at one centre in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailChiu, SS:ssschiu@hkucc.hku.hken_US
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_US
dc.identifier.authorityChiu, SS=rp00421en_US
dc.identifier.authorityLau, YL=rp00361en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33746364164en_US
dc.identifier.hkuros120573-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33746364164&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume11en_US
dc.identifier.issue3en_US
dc.identifier.spage215en_US
dc.identifier.epage222+265en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridChiu, SS=7202291500en_US
dc.identifier.scopusauthoridLau, YL=7201403380en_US

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