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Article: Developmental definition of MSCs: New insights into pending questions
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TitleDevelopmental definition of MSCs: New insights into pending questions
 
AuthorsHuang, S2
Leung, V2
Peng, S2
Li, L2
Lu, FJ2
Wang, T2
Lu, W2
Cheung, KMC2
Zhou, G2 1
 
Issue Date2011
 
PublisherMary Ann Liebert, Inc. Publishers. The Journal's web site is located at http://www.liebertpub.com/clo
 
CitationCellular Reprogramming, 2011, v. 13 n. 6, p. 465-472 [How to Cite?]
DOI: http://dx.doi.org/10.1089/cell.2011.0045
 
AbstractMesenchymal stem cells (MSCs) are a rare heterogeneous population of multipotent cells that can be isolated from many different adult and fetal tissues. They exhibit the capacity to give rise to cells of multiple lineages and are defined by their phenotype and functional properties, such as spindle-shaped morphology, adherence to plastic, immune response modulation capacity, and multilineage differentiation potential. Accordingly, MSCs have a wide range of promising applications in the treatment of autoimmune diseases, tissue repair, and regeneration. Recent studies have shed some light on the exact identity and native distribution of MSCs, whereas controversial results are still being reported, indicating the need for further review on their definition and origin. In this article, we summarize the important progress and describe some of our own relevant work on the developmental definition of MSCs. © 2011 Mary Ann Liebert, Inc.
 
ISSN2152-4971
2013 Impact Factor: 2.345
 
DOIhttp://dx.doi.org/10.1089/cell.2011.0045
 
PubMed Central IDPMC3229822
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorHuang, S
 
dc.contributor.authorLeung, V
 
dc.contributor.authorPeng, S
 
dc.contributor.authorLi, L
 
dc.contributor.authorLu, FJ
 
dc.contributor.authorWang, T
 
dc.contributor.authorLu, W
 
dc.contributor.authorCheung, KMC
 
dc.contributor.authorZhou, G
 
dc.date.accessioned2012-10-30T06:05:58Z
 
dc.date.available2012-10-30T06:05:58Z
 
dc.date.issued2011
 
dc.description.abstractMesenchymal stem cells (MSCs) are a rare heterogeneous population of multipotent cells that can be isolated from many different adult and fetal tissues. They exhibit the capacity to give rise to cells of multiple lineages and are defined by their phenotype and functional properties, such as spindle-shaped morphology, adherence to plastic, immune response modulation capacity, and multilineage differentiation potential. Accordingly, MSCs have a wide range of promising applications in the treatment of autoimmune diseases, tissue repair, and regeneration. Recent studies have shed some light on the exact identity and native distribution of MSCs, whereas controversial results are still being reported, indicating the need for further review on their definition and origin. In this article, we summarize the important progress and describe some of our own relevant work on the developmental definition of MSCs. © 2011 Mary Ann Liebert, Inc.
 
dc.description.naturePublished_or_final_version
 
dc.identifier.citationCellular Reprogramming, 2011, v. 13 n. 6, p. 465-472 [How to Cite?]
DOI: http://dx.doi.org/10.1089/cell.2011.0045
 
dc.identifier.doihttp://dx.doi.org/10.1089/cell.2011.0045
 
dc.identifier.epage472
 
dc.identifier.issn2152-4971
2013 Impact Factor: 2.345
 
dc.identifier.issue6
 
dc.identifier.pmcidPMC3229822
 
dc.identifier.pmid21919705
 
dc.identifier.scopuseid_2-s2.0-83255166464
 
dc.identifier.spage465
 
dc.identifier.urihttp://hdl.handle.net/10722/170189
 
dc.identifier.volume13
 
dc.languageeng
 
dc.publisherMary Ann Liebert, Inc. Publishers. The Journal's web site is located at http://www.liebertpub.com/clo
 
dc.publisher.placeUnited States
 
dc.relation.ispartofCellular Reprogramming
 
dc.relation.referencesReferences in Scopus
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.rightsThis is a copy of an article published in the [Cellular Reprogramming] © [2011] [copyright Mary Ann Liebert, Inc.]; [Cellular Reprogramming] is available online at: http://www.liebertonline.com.
 
dc.subject.meshAdult
 
dc.subject.meshAnimals
 
dc.subject.meshAutoimmune Diseases - Immunology - Therapy
 
dc.subject.meshCell Differentiation - Physiology
 
dc.subject.meshHumans
 
dc.subject.meshMesenchymal Stem Cell Transplantation
 
dc.subject.meshMesenchymal Stem Cells - Cytology - Physiology
 
dc.subject.meshMultipotent Stem Cells - Cytology - Physiology
 
dc.subject.meshRegeneration - Physiology
 
dc.titleDevelopmental definition of MSCs: New insights into pending questions
 
dc.typeArticle
 
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<contributor.author>Lu, FJ</contributor.author>
<contributor.author>Wang, T</contributor.author>
<contributor.author>Lu, W</contributor.author>
<contributor.author>Cheung, KMC</contributor.author>
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Author Affiliations
  1. Shenzhen University
  2. The University of Hong Kong