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Article: Vertebral augmentation with a novel Vessel-X bone void filling container system and bioactive bone cement

TitleVertebral augmentation with a novel Vessel-X bone void filling container system and bioactive bone cement
Authors
Issue Date2007
PublisherLippincott, Williams & Wilkins. The Journal's web site is located at http://www.spinejournal.com
Citation
Spine, 2007, v. 32 n. 19, p. 2076-2082 How to Cite?
AbstractSTUDY DESIGN. Evaluation of a novel, leakage-free vertebroplastic instrumentation by fresh cadaveric studies. OBJECTIVES. To compare Vessel-X, a novel percutaneous bone void filling container system, with conventional kyphoplasty in restoring strength, stiffness, and height in experimentally induced vertebral compressive fractures and morphologically determine the cement distribution. SUMMARY OF BACKGROUND DATA. Clinically, both vertebroplasty and kyphoplasty perform well in reinforcement and pain relief. One of the shortcomings, however, is the risk of cement leakage. Vessel-X is a novel bone expander and bone void filler combined instrumentation for vertebral augmentation requiring evaluation. METHODS. A total of 28 fresh-frozen vertebral specimens were randomly assigned to 4 groups for testing: unipedicular kyphoplsty, bipedicular kyphoplsty, unipedicular Vessel-X, and bipedicular Vessel-X. Compressive fractures were experimentally created on each vertebra after determining the bone mineral density. Kyphoplasty and Vessel-X were performed using bioactive bone cement (SrHAC) under C-arm fluoroscopy and compared by compression testing to measure the effects of augmentation. Morphologic observations were also performed to determine the cement distribution and vertebral height restoration. RESULTS. There was no significant difference in bone mineral density, initial strength, and stiffness in any of the groups. Furthermore, no significant difference was observed in total cement volume in intragroup comparison within the unipedicular or bipedicular groups. Vessel-X bone filler container could expand well and contain most of the cement. The height restoration ranged from 88.5% to 96.4% in all groups. The augmented strength with unipedicular and bipedicular injections reached 3651.57 N and 4833.73 N, respectively. Stiffness with bipedicular injection was significantly higher than that of unipedicular injection. CONCLUSION. Vessel-X was comparable to kyphoplasty in restoring the mechanical properties and height of the fractured vertebrae. Interestingly, Vessel-X instrumentation showed considerably less cement leakage and better cement placement in the vertebral body. Therefore, it could be a leakage controllable technique in percutaneous vertebral augmentation. © 2007 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/170115
ISSN
2015 Impact Factor: 2.439
2015 SCImago Journal Rankings: 1.459
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZheng, Zen_US
dc.contributor.authorLuk, KDKen_US
dc.contributor.authorKuang, Gen_US
dc.contributor.authorLi, Zen_US
dc.contributor.authorLin, Jen_US
dc.contributor.authorLam, WMen_US
dc.contributor.authorCheung, KMCen_US
dc.contributor.authorLu, WWen_US
dc.date.accessioned2012-10-30T06:05:25Z-
dc.date.available2012-10-30T06:05:25Z-
dc.date.issued2007en_US
dc.identifier.citationSpine, 2007, v. 32 n. 19, p. 2076-2082en_US
dc.identifier.issn0362-2436en_US
dc.identifier.urihttp://hdl.handle.net/10722/170115-
dc.description.abstractSTUDY DESIGN. Evaluation of a novel, leakage-free vertebroplastic instrumentation by fresh cadaveric studies. OBJECTIVES. To compare Vessel-X, a novel percutaneous bone void filling container system, with conventional kyphoplasty in restoring strength, stiffness, and height in experimentally induced vertebral compressive fractures and morphologically determine the cement distribution. SUMMARY OF BACKGROUND DATA. Clinically, both vertebroplasty and kyphoplasty perform well in reinforcement and pain relief. One of the shortcomings, however, is the risk of cement leakage. Vessel-X is a novel bone expander and bone void filler combined instrumentation for vertebral augmentation requiring evaluation. METHODS. A total of 28 fresh-frozen vertebral specimens were randomly assigned to 4 groups for testing: unipedicular kyphoplsty, bipedicular kyphoplsty, unipedicular Vessel-X, and bipedicular Vessel-X. Compressive fractures were experimentally created on each vertebra after determining the bone mineral density. Kyphoplasty and Vessel-X were performed using bioactive bone cement (SrHAC) under C-arm fluoroscopy and compared by compression testing to measure the effects of augmentation. Morphologic observations were also performed to determine the cement distribution and vertebral height restoration. RESULTS. There was no significant difference in bone mineral density, initial strength, and stiffness in any of the groups. Furthermore, no significant difference was observed in total cement volume in intragroup comparison within the unipedicular or bipedicular groups. Vessel-X bone filler container could expand well and contain most of the cement. The height restoration ranged from 88.5% to 96.4% in all groups. The augmented strength with unipedicular and bipedicular injections reached 3651.57 N and 4833.73 N, respectively. Stiffness with bipedicular injection was significantly higher than that of unipedicular injection. CONCLUSION. Vessel-X was comparable to kyphoplasty in restoring the mechanical properties and height of the fractured vertebrae. Interestingly, Vessel-X instrumentation showed considerably less cement leakage and better cement placement in the vertebral body. Therefore, it could be a leakage controllable technique in percutaneous vertebral augmentation. © 2007 Lippincott Williams & Wilkins, Inc.en_US
dc.languageengen_US
dc.publisherLippincott, Williams & Wilkins. The Journal's web site is located at http://www.spinejournal.comen_US
dc.relation.ispartofSpineen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshBone Cements - Therapeutic Useen_US
dc.subject.meshBone Densityen_US
dc.subject.meshCadaveren_US
dc.subject.meshCompressive Strengthen_US
dc.subject.meshDurapatite - Therapeutic Useen_US
dc.subject.meshEquipment Designen_US
dc.subject.meshFemaleen_US
dc.subject.meshFracture Fixation, Internal - Instrumentationen_US
dc.subject.meshFractures, Compression - Radiography - Surgeryen_US
dc.subject.meshHumansen_US
dc.subject.meshLumbar Vertebrae - Radiography - Surgeryen_US
dc.subject.meshMaleen_US
dc.subject.meshProsthesis Failureen_US
dc.subject.meshSpinal Fractures - Radiography - Surgeryen_US
dc.subject.meshStress, Mechanicalen_US
dc.subject.meshThoracic Vertebrae - Radiography - Surgeryen_US
dc.titleVertebral augmentation with a novel Vessel-X bone void filling container system and bioactive bone cementen_US
dc.typeArticleen_US
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_US
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_US
dc.identifier.emailLu, WW:wwlu@hku.hken_US
dc.identifier.authorityLuk, KDK=rp00333en_US
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.identifier.authorityLu, WW=rp00411en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/BRS.0b013e3181453f64en_US
dc.identifier.pmid17762808-
dc.identifier.scopuseid_2-s2.0-34548426435en_US
dc.identifier.hkuros145979-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34548426435&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume32en_US
dc.identifier.issue19en_US
dc.identifier.spage2076en_US
dc.identifier.epage2082en_US
dc.identifier.isiWOS:000249353800007-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridZheng, Z=7403007434en_US
dc.identifier.scopusauthoridLuk, KDK=7201921573en_US
dc.identifier.scopusauthoridKuang, G=16024818800en_US
dc.identifier.scopusauthoridLi, Z=35784563200en_US
dc.identifier.scopusauthoridLin, J=37054054500en_US
dc.identifier.scopusauthoridLam, WM=20734707900en_US
dc.identifier.scopusauthoridCheung, KMC=7402406754en_US
dc.identifier.scopusauthoridLu, WW=7404215221en_US

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