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Article: Angiomodulatory and neurological effects of ginsenosides

TitleAngiomodulatory and neurological effects of ginsenosides
Authors
KeywordsAngiogenesis
Angiotherapy
Cognitive functions
Ginseng
Ginsenosides
Neuroprotection
Steroid hormone receptors
Issue Date2007
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmc/index.htm
Citation
Current Medicinal Chemistry, 2007, v. 14 n. 12, p. 1371-1380 How to Cite?
AbstractPanax ginseng C.A. Meyer, one of the most popular and valued herbs, has been used extensively in traditional Chinese medicine for thousands of years. More than thirty ginsenosides, the pharmacologically active ingredients in ginseng, have been identified with various sugar moieties attached at the C-3, C-6 and C-20 positions of the steroidal skeleton. We herein review the current literature on the pharmacological effects of ginsenosides on the modulation of angiogenesis, dysregulations of which contribute towards many pathological conditions. Regarding the adaptogenic property of ginseng, the effects of ginsenosides on central nervous system are also discussed. Recent researches have pointed to the steroid hormone receptors as the target molecules to elicit the diverse cellular and physiological activities of ginseng. We believe that understanding the interaction between ginsenosides and various steroid hormone receptors may provide clues to unravel the secret of ginseng. © 2007 Bentham Science Publishers Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/169849
ISSN
2015 Impact Factor: 3.455
2015 SCImago Journal Rankings: 0.842
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLeung, KWen_HK
dc.contributor.authorYung, KKLen_HK
dc.contributor.authorMak, NKen_HK
dc.contributor.authorYue, PYKen_HK
dc.contributor.authorLuo, HBen_HK
dc.contributor.authorCheng, YKen_HK
dc.contributor.authorFan, TPDen_HK
dc.contributor.authorYueng, HWen_HK
dc.contributor.authorNg, TBen_HK
dc.contributor.authorWong, RNSen_HK
dc.date.accessioned2012-10-25T04:57:03Z-
dc.date.available2012-10-25T04:57:03Z-
dc.date.issued2007en_HK
dc.identifier.citationCurrent Medicinal Chemistry, 2007, v. 14 n. 12, p. 1371-1380en_HK
dc.identifier.issn0929-8673en_HK
dc.identifier.urihttp://hdl.handle.net/10722/169849-
dc.description.abstractPanax ginseng C.A. Meyer, one of the most popular and valued herbs, has been used extensively in traditional Chinese medicine for thousands of years. More than thirty ginsenosides, the pharmacologically active ingredients in ginseng, have been identified with various sugar moieties attached at the C-3, C-6 and C-20 positions of the steroidal skeleton. We herein review the current literature on the pharmacological effects of ginsenosides on the modulation of angiogenesis, dysregulations of which contribute towards many pathological conditions. Regarding the adaptogenic property of ginseng, the effects of ginsenosides on central nervous system are also discussed. Recent researches have pointed to the steroid hormone receptors as the target molecules to elicit the diverse cellular and physiological activities of ginseng. We believe that understanding the interaction between ginsenosides and various steroid hormone receptors may provide clues to unravel the secret of ginseng. © 2007 Bentham Science Publishers Ltd.en_HK
dc.languageengen_US
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cmc/index.htmen_HK
dc.relation.ispartofCurrent Medicinal Chemistryen_HK
dc.subjectAngiogenesisen_HK
dc.subjectAngiotherapyen_HK
dc.subjectCognitive functionsen_HK
dc.subjectGinsengen_HK
dc.subjectGinsenosidesen_HK
dc.subjectNeuroprotectionen_HK
dc.subjectSteroid hormone receptorsen_HK
dc.subject.meshAngiogenesis Inhibitors - Pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCognition - Drug Effectsen_US
dc.subject.meshEndothelium, Vascular - Cytology - Drug Effectsen_US
dc.subject.meshGinsenosides - Pharmacology - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Molecularen_US
dc.subject.meshNeovascularization, Physiologic - Drug Effectsen_US
dc.subject.meshNeurodegenerative Diseases - Drug Therapyen_US
dc.subject.meshNeuroprotective Agents - Pharmacologyen_US
dc.titleAngiomodulatory and neurological effects of ginsenosidesen_HK
dc.typeArticleen_HK
dc.identifier.emailLeung, KW: kwleung1@hku.hken_HK
dc.identifier.authorityLeung, KW=rp01674en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.2174/092986707780597916en_HK
dc.identifier.pmid17504218-
dc.identifier.scopuseid_2-s2.0-34248559426en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34248559426&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume14en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1371en_HK
dc.identifier.epage1380en_HK
dc.identifier.isiWOS:000245794300006-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridLeung, KW=13106059300en_HK
dc.identifier.scopusauthoridYung, KKL=13605496000en_HK
dc.identifier.scopusauthoridMak, NK=35587830100en_HK
dc.identifier.scopusauthoridYue, PYK=8570616200en_HK
dc.identifier.scopusauthoridLuo, HB=7401480124en_HK
dc.identifier.scopusauthoridCheng, YK=9133925600en_HK
dc.identifier.scopusauthoridFan, TPD=7202528295en_HK
dc.identifier.scopusauthoridYueng, HW=16310968400en_HK
dc.identifier.scopusauthoridNg, TB=35311803300en_HK
dc.identifier.scopusauthoridWong, RNS=7402126957en_HK
dc.identifier.citeulike1265197-

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