Article: Medication-induced acute angle closure attack

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleMedication-induced acute angle closure attack
AuthorsLai, JSM1
Gangwani, RA1
Issue Date2012
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
CitationHong Kong Medical Journal, 2012, v. 18 n. 2, p. 139-145 [How to Cite?]
AbstractOBJECTIVE: To review acute angle closure attacks induced by local and systemic medications. DATA SOURCES: PubMed literature searches up to August 2011. STUDY SELECTION: The following key words were used for the search: 'drug', 'iatrogenic', 'acute angle closure glaucoma'. DATA EXTRACTION: A total of 86 articles were retrieved using the key words. Only those concerning acute angle closure attack triggered by local or systemic drug administration were included. For articles on the same or related topics, those published at later or more recent dates were selected. As a result, 44 articles were included and formed the basis of this review. DATA SYNTHESIS: An acute attack of angle closure can be triggered by dilatation of the pupil, by anatomical changes in the ciliary body and iris, or by movement of the iris-lens diaphragm. Local and systemic medications that cause these changes have the potential to precipitate an attack of acute angle closure. The risk is higher in subjects who are predisposed to the development of angle closure. Many pharmaceutical agents including ophthalmic eyedrops and systemic drugs prescribed by general practitioners and various specialists (in psychiatry, otorhinolaryngology, ophthalmology, medicine, and anaesthesia) can precipitate an acute angle closure attack. The medications include: anti-histamines, anti-epileptics, antiparkinsonian agents, antispasmolytic drugs, mydriatic agents, sympathetic agents, and botulinum toxin. CONCLUSION: Since acute angle closure attack is a potentially blinding eye disease, it is extremely important to be vigilant and aware of ophthalmic and systemic medications that can lead to such attacks in predisposed subjects and to diagnose the condition when it occurs.
DescriptionAuthor Chinese name: Jimmy SM Lai 黎少明, Rita A Gangwani
ISSN1024-2708
2011 SCImago Journal Rankings: 0.054
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorLai, JSM
dc.contributor.authorGangwani, RA
dc.date.accessioned2012-10-18T09:00:35Z
dc.date.available2012-10-18T09:00:35Z
dc.date.issued2012
dc.description.abstractOBJECTIVE: To review acute angle closure attacks induced by local and systemic medications. DATA SOURCES: PubMed literature searches up to August 2011. STUDY SELECTION: The following key words were used for the search: 'drug', 'iatrogenic', 'acute angle closure glaucoma'. DATA EXTRACTION: A total of 86 articles were retrieved using the key words. Only those concerning acute angle closure attack triggered by local or systemic drug administration were included. For articles on the same or related topics, those published at later or more recent dates were selected. As a result, 44 articles were included and formed the basis of this review. DATA SYNTHESIS: An acute attack of angle closure can be triggered by dilatation of the pupil, by anatomical changes in the ciliary body and iris, or by movement of the iris-lens diaphragm. Local and systemic medications that cause these changes have the potential to precipitate an attack of acute angle closure. The risk is higher in subjects who are predisposed to the development of angle closure. Many pharmaceutical agents including ophthalmic eyedrops and systemic drugs prescribed by general practitioners and various specialists (in psychiatry, otorhinolaryngology, ophthalmology, medicine, and anaesthesia) can precipitate an acute angle closure attack. The medications include: anti-histamines, anti-epileptics, antiparkinsonian agents, antispasmolytic drugs, mydriatic agents, sympathetic agents, and botulinum toxin. CONCLUSION: Since acute angle closure attack is a potentially blinding eye disease, it is extremely important to be vigilant and aware of ophthalmic and systemic medications that can lead to such attacks in predisposed subjects and to diagnose the condition when it occurs.
dc.description.naturepublished_or_final_version
dc.descriptionAuthor Chinese name: Jimmy SM Lai 黎少明, Rita A Gangwani
dc.identifier.citationHong Kong Medical Journal, 2012, v. 18 n. 2, p. 139-145 [How to Cite?]
dc.identifier.epage145
dc.identifier.hkuros212131
dc.identifier.issn1024-2708
2011 SCImago Journal Rankings: 0.054
dc.identifier.issue2
dc.identifier.pmid22477738
dc.identifier.scopuseid_2-s2.0-84861170965
dc.identifier.spage139
dc.identifier.urihttp://hdl.handle.net/10722/169512
dc.identifier.volume18
dc.languageeng
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong Medical Journal
dc.relation.referencesReferences in Scopus
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
dc.subject.meshAcute Disease
dc.subject.meshAnticonvulsants - Adverse Effects
dc.subject.meshAntidepressive Agents - Adverse Effects
dc.subject.meshCholinergic Antagonists - Adverse Effects
dc.subject.meshGlaucoma, Angle-Closure - Chemically Induced
dc.subject.meshHumans
dc.subject.meshMydriatics - Adverse Effects
dc.subject.meshRisk Factors
dc.titleMedication-induced acute angle closure attack
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong