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Article: Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children

TitleRandomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children
Authors
KeywordsChild
Dental caries
Fluoride
Glass ionomer cement
Preventive dentistry
Issue Date2012
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent
Citation
Journal of Dentistry, 2012, v. 40 n. 11, p. 962-967 How to Cite?
AbstractOBJECTIVE: To compare the effectiveness of annual topical application of silver diamine fluoride (SDF) solution, semi-annual topical application of SDF solution, and annual application of a flowable high fluoride-releasing glass ionomer in arresting active dentine caries in primary teeth. METHODS: A total of 212 children, aged 3-4 years, were randomly allocated to one of three groups for treatment of carious dentine cavities in their primary teeth: Gp1-annual application of SDF, Gp2-semi-annual application of SDF, and Gp3-annual application of glass ionomer. Follow-up examinations were carried out every six months to assess whether the treated caries lesions had become arrested. RESULTS: After 24 months, 181 (85%) children remained in the study. The caries arrest rates were 79%, 91% and 82% for Gp1, Gp2 and Gp3, respectively (p=0.007). In the logistic regression model using GEE to adjust for clustering effect, higher caries arrest rates were found in lesions treated in Gp2 (OR=2.98, p=0.007), those in anterior teeth (OR=5.55, p<0.001), and those in buccal/lingual smooth surfaces (OR=15.6, p=0.004). CONCLUSION: Annual application of either SDF solution or high fluoride-releasing glass ionomer can arrest active dentine caries. Increasing the frequency of application to every 6 months can increase the caries arrest rate of SDF application. CLINICAL SIGNIFICANCE: Arrest of active dentine caries in primary teeth by topical application of SDF solution can be enhanced by increasing the frequency of application from annually to every 6 months, whereas annual paint-on of a flowable glass ionomer can also arrest active dentine caries and may provide a more aesthetic outcome.
Persistent Identifierhttp://hdl.handle.net/10722/169164
ISSN
2015 Impact Factor: 3.109
2015 SCImago Journal Rankings: 1.029
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZhi, QHen_US
dc.contributor.authorLo, ECMen_US
dc.contributor.authorLin, HCen_US
dc.date.accessioned2012-10-18T08:44:54Z-
dc.date.available2012-10-18T08:44:54Z-
dc.date.issued2012en_US
dc.identifier.citationJournal of Dentistry, 2012, v. 40 n. 11, p. 962-967en_US
dc.identifier.issn0300-5712-
dc.identifier.urihttp://hdl.handle.net/10722/169164-
dc.description.abstractOBJECTIVE: To compare the effectiveness of annual topical application of silver diamine fluoride (SDF) solution, semi-annual topical application of SDF solution, and annual application of a flowable high fluoride-releasing glass ionomer in arresting active dentine caries in primary teeth. METHODS: A total of 212 children, aged 3-4 years, were randomly allocated to one of three groups for treatment of carious dentine cavities in their primary teeth: Gp1-annual application of SDF, Gp2-semi-annual application of SDF, and Gp3-annual application of glass ionomer. Follow-up examinations were carried out every six months to assess whether the treated caries lesions had become arrested. RESULTS: After 24 months, 181 (85%) children remained in the study. The caries arrest rates were 79%, 91% and 82% for Gp1, Gp2 and Gp3, respectively (p=0.007). In the logistic regression model using GEE to adjust for clustering effect, higher caries arrest rates were found in lesions treated in Gp2 (OR=2.98, p=0.007), those in anterior teeth (OR=5.55, p<0.001), and those in buccal/lingual smooth surfaces (OR=15.6, p=0.004). CONCLUSION: Annual application of either SDF solution or high fluoride-releasing glass ionomer can arrest active dentine caries. Increasing the frequency of application to every 6 months can increase the caries arrest rate of SDF application. CLINICAL SIGNIFICANCE: Arrest of active dentine caries in primary teeth by topical application of SDF solution can be enhanced by increasing the frequency of application from annually to every 6 months, whereas annual paint-on of a flowable glass ionomer can also arrest active dentine caries and may provide a more aesthetic outcome.-
dc.languageengen_US
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jdent-
dc.relation.ispartofJournal of Dentistryen_US
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Journal of Dentistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Dentistry, 2012, v. 40 n. 11, p. 962-967. DOI: 10.1016/j.jdent.2012.08.002-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectChild-
dc.subjectDental caries-
dc.subjectFluoride-
dc.subjectGlass ionomer cement-
dc.subjectPreventive dentistry-
dc.titleRandomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool childrenen_US
dc.typeArticleen_US
dc.identifier.emailLo, ECM: edward-lo@hku.hken_US
dc.identifier.authorityLo, ECM=rp00015en_US
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.jdent.2012.08.002-
dc.identifier.pmid22892463-
dc.identifier.scopuseid_2-s2.0-84866734115-
dc.identifier.hkuros212009en_US
dc.identifier.volume40en_US
dc.identifier.issue11-
dc.identifier.spage962en_US
dc.identifier.epage967en_US
dc.identifier.isiWOS:000309291200012-
dc.publisher.placeUnited Kingdom-
dc.identifier.citeulike11790229-

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