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Article: Chinese herbal medicine and cognitive and emotional functions during 60-day head-down bed rest

TitleChinese herbal medicine and cognitive and emotional functions during 60-day head-down bed rest
Authors
Issue Date2010
PublisherAerospace Medical Association. The Journal's web site is located at http://www.asma.org/journal/
Citation
Aviation Space And Environmental Medicine, 2010, v. 81 n. 8, p. 754-760 How to Cite?
AbstractIntroduction: This study aimed to test the efficacy of an oral-intake Chinese herbal medicine in enhancing the cognitive and emotional functions of individuals in a simulated microgravity condition. The herbal medicine consisted of ingredients that may enhance cognitive and emotional functions in an extreme environment. Methods: There were 14 healthy male subjects who were randomly assigned to a Chinese medicine (CMG) or a control (CG) group and underwent a 60-d 6° head-down bed-rest protocol. Testing was conducted before (Day -3), throughout (Days 3, 7, 20, 40, 57), and after (Days +3, +10) the bedrest protocol. The Arrow Test, Balloon Analog Risk Task (BART), Dual Task, and Affect Grid were administered on all testing days. Results: The CMG demonstrated consistently higher scores on the BART (Days 20 to 40; Mean: CMG, 43.0 to 46.2 and CG, 30.2 to 25.5) and lower levels of arousal on the Affect Grid (Days 7 to 40; Mean: CMG, 6.9 to 6.7 and CG, 8.1 to 8.0) than did the CG. The CMG showed significantly higher performance on the Arrow Test (incompatible condition) at the beginning of the bed-rest period (Day 3 to 7; Mean: 799.5 ms and 763.1 ms, respectively) which was not observed in the CG. Discussions: Results suggest that the Chinese herbal medicine may calm subjects' emotions by lowering the arousal level. At the same time, it may have produced positive effects in enhancing advantageous risk-taking and to a lesser extent self-regulatory behaviors (in the early phase). Copyright © by the Aerospace Medical Association.
Persistent Identifierhttp://hdl.handle.net/10722/169079
ISSN
2015 Impact Factor: 0.755
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, CCHen_US
dc.contributor.authorLi, YZen_US
dc.contributor.authorGuo, LGen_US
dc.contributor.authorZhou, XNen_US
dc.contributor.authorLuo, YJen_US
dc.contributor.authorLee, TMCen_US
dc.date.accessioned2012-10-08T03:41:32Z-
dc.date.available2012-10-08T03:41:32Z-
dc.date.issued2010en_US
dc.identifier.citationAviation Space And Environmental Medicine, 2010, v. 81 n. 8, p. 754-760en_US
dc.identifier.issn0095-6562en_US
dc.identifier.urihttp://hdl.handle.net/10722/169079-
dc.description.abstractIntroduction: This study aimed to test the efficacy of an oral-intake Chinese herbal medicine in enhancing the cognitive and emotional functions of individuals in a simulated microgravity condition. The herbal medicine consisted of ingredients that may enhance cognitive and emotional functions in an extreme environment. Methods: There were 14 healthy male subjects who were randomly assigned to a Chinese medicine (CMG) or a control (CG) group and underwent a 60-d 6° head-down bed-rest protocol. Testing was conducted before (Day -3), throughout (Days 3, 7, 20, 40, 57), and after (Days +3, +10) the bedrest protocol. The Arrow Test, Balloon Analog Risk Task (BART), Dual Task, and Affect Grid were administered on all testing days. Results: The CMG demonstrated consistently higher scores on the BART (Days 20 to 40; Mean: CMG, 43.0 to 46.2 and CG, 30.2 to 25.5) and lower levels of arousal on the Affect Grid (Days 7 to 40; Mean: CMG, 6.9 to 6.7 and CG, 8.1 to 8.0) than did the CG. The CMG showed significantly higher performance on the Arrow Test (incompatible condition) at the beginning of the bed-rest period (Day 3 to 7; Mean: 799.5 ms and 763.1 ms, respectively) which was not observed in the CG. Discussions: Results suggest that the Chinese herbal medicine may calm subjects' emotions by lowering the arousal level. At the same time, it may have produced positive effects in enhancing advantageous risk-taking and to a lesser extent self-regulatory behaviors (in the early phase). Copyright © by the Aerospace Medical Association.en_US
dc.languageengen_US
dc.publisherAerospace Medical Association. The Journal's web site is located at http://www.asma.org/journal/en_US
dc.relation.ispartofAviation Space and Environmental Medicineen_US
dc.subject.meshAdulten_US
dc.subject.meshAttentionen_US
dc.subject.meshBed Resten_US
dc.subject.meshCognitionen_US
dc.subject.meshDecision Makingen_US
dc.subject.meshDrugs, Chinese Herbal - Therapeutic Useen_US
dc.subject.meshHead-Down Tilten_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshPsychotropic Drugs - Therapeutic Useen_US
dc.subject.meshRisk-Takingen_US
dc.subject.meshWeightlessness Countermeasuresen_US
dc.subject.meshWeightlessness Simulation - Psychologyen_US
dc.subject.meshYoung Adulten_US
dc.titleChinese herbal medicine and cognitive and emotional functions during 60-day head-down bed resten_US
dc.typeArticleen_US
dc.identifier.emailLee, TMC:tmclee@hku.hken_US
dc.identifier.authorityLee, TMC=rp00564en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.3357/ASEM.2727.2010en_US
dc.identifier.pmid20681235-
dc.identifier.scopuseid_2-s2.0-77954974513en_US
dc.identifier.hkuros173812-
dc.identifier.hkuros173829-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77954974513&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume81en_US
dc.identifier.issue8en_US
dc.identifier.spage754en_US
dc.identifier.epage760en_US
dc.identifier.isiWOS:000280428300005-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChan, CCH=16244174500en_US
dc.identifier.scopusauthoridLi, YZ=36062875400en_US
dc.identifier.scopusauthoridGuo, LG=35218848000en_US
dc.identifier.scopusauthoridZhou, XN=36555142300en_US
dc.identifier.scopusauthoridLuo, YJ=7404332638en_US
dc.identifier.scopusauthoridLee, TMC=7501437381en_US
dc.identifier.citeulike7617819-

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