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Article: Palladium-Catalyzed highly diastereoselective oxidative cascade cyclization reactions

TitlePalladium-Catalyzed highly diastereoselective oxidative cascade cyclization reactions
Authors
Yip, KTZhu, NYYang, D
Issue Date2009
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.html
Citation
Organic Letters, 2009, v. 11 n. 9, p. 1911-1914 How to Cite?
DOI: http://dx.doi.org/10.1021/ol900355h
AbstractIsoquinoline and quinoline have been discovered as novel ligands for palladium-catalyzed oxidative cascade cyclization reactions. With our new catalyst systems (Pd(OAc)2/isoquinoline or quinoline), unsaturated anilides cyclize under an oxygen atmosphere (1 atm) to furnish structurally versatile indoline derivatives in good yields. One C-N bond and two C-C bonds are formed in a single step with excellent diastereoselectivities (dr> 24:1). © 2009 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/168378
ISSN
1523-7060
2021 Impact Factor: 6.072
2020 SCImago Journal Rankings: 1.940
ISI Accession Number ID
WOS:000265529000012
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorYip, KTen_HK
dc.contributor.authorZhu, NYen_HK
dc.contributor.authorYang, Den_HK
dc.date.accessioned2012-10-08T03:18:12Z-
dc.date.available2012-10-08T03:18:12Z-
dc.date.issued2009en_HK
dc.identifier.citationOrganic Letters, 2009, v. 11 n. 9, p. 1911-1914en_HK
dc.identifier.issn1523-7060en_HK
dc.identifier.urihttp://hdl.handle.net/10722/168378-
dc.description.abstractIsoquinoline and quinoline have been discovered as novel ligands for palladium-catalyzed oxidative cascade cyclization reactions. With our new catalyst systems (Pd(OAc)2/isoquinoline or quinoline), unsaturated anilides cyclize under an oxygen atmosphere (1 atm) to furnish structurally versatile indoline derivatives in good yields. One C-N bond and two C-C bonds are formed in a single step with excellent diastereoselectivities (dr> 24:1). © 2009 American Chemical Society.en_HK
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/orlef7/index.htmlen_HK
dc.relation.ispartofOrganic Lettersen_HK
dc.titlePalladium-Catalyzed highly diastereoselective oxidative cascade cyclization reactionsen_HK
dc.typeArticleen_HK
dc.identifier.emailYip, KT: billyyip@graduate.hku.hken_HK
dc.identifier.emailZhu, NY: nzhu@hkucc.hku.hken_HK
dc.identifier.emailYang, D: yangdan@hku.hken_HK
dc.identifier.authorityYip, KT=rp00832en_HK
dc.identifier.authorityZhu, NY=rp00845en_HK
dc.identifier.authorityYang, D=rp00825en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/ol900355hen_HK
dc.identifier.pmid19338292-
dc.identifier.scopuseid_2-s2.0-66149101004en_HK
dc.identifier.hkuros160416-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-66149101004&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume11en_HK
dc.identifier.issue9en_HK
dc.identifier.spage1911en_HK
dc.identifier.epage1914en_HK
dc.identifier.isiWOS:000265529000012-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYip, KT=10440172200en_HK
dc.identifier.scopusauthoridZhu, NY=7201449530en_HK
dc.identifier.scopusauthoridYang, D=7404800756en_HK
dc.identifier.issnl1523-7052-

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