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Article: Synthesis and antitumor activity of tanshinone analogues

TitleSynthesis and antitumor activity of tanshinone analogues
Authors
Aisa, HALu, WCai, JC
KeywordsAnalogues
Synthesis
Tanshinone
Issue Date2003
PublisherZhongguo Kexueyuan, Shanghai Youji Huaxue Yanjiusuo. The Journal's web site is located at http://www.sioc-journal.cn/zghx/index_en.asp
Citation
Chinese Journal Of Chemistry, 2003, v. 21 n. 7, p. 720-722 How to Cite?
DOI: http://dx.doi.org/10.1002/cjoc.20030210703
Abstract8,8-Dimethyl-5,6,7,8-tetrahydrophenanthrene-3,4-dione (3) and 8,8-dimethyl-2-(1-hydroxy ethyl)-5,6,7,8-tetrahydrophenanthrene-3,4-dione (4), two analogues of the antitumor active tanshinone, were synthesized from anisole. The synthesized compounds 3 and 4 were shown to be highly active against leukemia P-388 cell line as assayed by in vitro MTT method.
Persistent Identifierhttp://hdl.handle.net/10722/168035
ISSN
1001-604X
2021 Impact Factor: 5.560
2020 SCImago Journal Rankings: 1.280
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorAisa, HAen_US
dc.contributor.authorLu, Wen_US
dc.contributor.authorCai, JCen_US
dc.date.accessioned2012-10-08T03:14:23Z-
dc.date.available2012-10-08T03:14:23Z-
dc.date.issued2003en_US
dc.identifier.citationChinese Journal Of Chemistry, 2003, v. 21 n. 7, p. 720-722en_US
dc.identifier.issn1001-604Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/168035-
dc.description.abstract8,8-Dimethyl-5,6,7,8-tetrahydrophenanthrene-3,4-dione (3) and 8,8-dimethyl-2-(1-hydroxy ethyl)-5,6,7,8-tetrahydrophenanthrene-3,4-dione (4), two analogues of the antitumor active tanshinone, were synthesized from anisole. The synthesized compounds 3 and 4 were shown to be highly active against leukemia P-388 cell line as assayed by in vitro MTT method.en_US
dc.languageengen_US
dc.publisherZhongguo Kexueyuan, Shanghai Youji Huaxue Yanjiusuo. The Journal's web site is located at http://www.sioc-journal.cn/zghx/index_en.aspen_US
dc.relation.ispartofChinese Journal of Chemistryen_US
dc.subjectAnaloguesen_US
dc.subjectSynthesisen_US
dc.subjectTanshinoneen_US
dc.titleSynthesis and antitumor activity of tanshinone analoguesen_US
dc.typeArticleen_US
dc.identifier.emailLu, W:luwei@hku.hken_US
dc.identifier.authorityLu, W=rp00754en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/cjoc.20030210703-
dc.identifier.scopuseid_2-s2.0-33748042967en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33748042967&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume21en_US
dc.identifier.issue7en_US
dc.identifier.spage720en_US
dc.identifier.epage722en_US
dc.publisher.placeChinaen_US
dc.identifier.scopusauthoridAisa, HA=13407354600en_US
dc.identifier.scopusauthoridLu, W=27868087600en_US
dc.identifier.scopusauthoridCai, JC=26643616800en_US
dc.identifier.issnl1001-604X-

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