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- Publisher Website: 10.1021/ja044493+
- Scopus: eid_2-s2.0-10344219514
- PMID: 15584729
- WOS: WOS:000225697000028
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Article: γ4-Aminoxy peptides as new peptidomimetic foldamers
Title | γ4-Aminoxy peptides as new peptidomimetic foldamers |
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Authors | |
Issue Date | 2004 |
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html |
Citation | Journal Of The American Chemical Society, 2004, v. 126 n. 49, p. 15980-15981 How to Cite? |
Abstract | The conformational properties of peptides 1-3 of γ-aminoxy acids have been investigated by using FT-IR, NMR spectroscopy, and X-ray crystallography. Diamide 1 consisting of unsubstituted γ-aminoxy acid cannot form intramolecular hydrogen bond. A novel γ N-O turn involving a 10-membered-ring intramolecular hydrogen bond between NH i+2 and CO i is formed in γ 4-aminoxy peptides 2 and 3. Triamides 3 prefers a new helical structure featuring two consecutive γ N-O turns. Therefore, γ 4-aminoxy peptides represent new peptidomimetic foldamers. Copyright © 2004 American Chemical Society. |
Persistent Identifier | http://hdl.handle.net/10722/167877 |
ISSN | 2023 Impact Factor: 14.4 2023 SCImago Journal Rankings: 5.489 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Chen, F | en_HK |
dc.contributor.author | Zhu, NY | en_HK |
dc.contributor.author | Yang, D | en_HK |
dc.date.accessioned | 2012-10-08T03:12:26Z | - |
dc.date.available | 2012-10-08T03:12:26Z | - |
dc.date.issued | 2004 | en_HK |
dc.identifier.citation | Journal Of The American Chemical Society, 2004, v. 126 n. 49, p. 15980-15981 | en_HK |
dc.identifier.issn | 0002-7863 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/167877 | - |
dc.description.abstract | The conformational properties of peptides 1-3 of γ-aminoxy acids have been investigated by using FT-IR, NMR spectroscopy, and X-ray crystallography. Diamide 1 consisting of unsubstituted γ-aminoxy acid cannot form intramolecular hydrogen bond. A novel γ N-O turn involving a 10-membered-ring intramolecular hydrogen bond between NH i+2 and CO i is formed in γ 4-aminoxy peptides 2 and 3. Triamides 3 prefers a new helical structure featuring two consecutive γ N-O turns. Therefore, γ 4-aminoxy peptides represent new peptidomimetic foldamers. Copyright © 2004 American Chemical Society. | en_HK |
dc.language | eng | en_US |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html | en_HK |
dc.relation.ispartof | Journal of the American Chemical Society | en_HK |
dc.subject.mesh | Amino Acids - Chemistry | en_US |
dc.subject.mesh | Biomimetic Materials - Chemistry | en_US |
dc.subject.mesh | Circular Dichroism | en_US |
dc.subject.mesh | Models, Molecular | en_US |
dc.subject.mesh | Nuclear Magnetic Resonance, Biomolecular | en_US |
dc.subject.mesh | Peptides - Chemistry | en_US |
dc.subject.mesh | Protein Folding | en_US |
dc.subject.mesh | Protein Structure, Secondary | en_US |
dc.subject.mesh | Spectroscopy, Fourier Transform Infrared | en_US |
dc.title | γ4-Aminoxy peptides as new peptidomimetic foldamers | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Zhu, NY: nzhu@hkucc.hku.hk | en_HK |
dc.identifier.email | Yang, D: yangdan@hku.hk | en_HK |
dc.identifier.authority | Zhu, NY=rp00845 | en_HK |
dc.identifier.authority | Yang, D=rp00825 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1021/ja044493+ | en_HK |
dc.identifier.pmid | 15584729 | - |
dc.identifier.scopus | eid_2-s2.0-10344219514 | en_HK |
dc.identifier.hkuros | 98424 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-10344219514&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 126 | en_HK |
dc.identifier.issue | 49 | en_HK |
dc.identifier.spage | 15980 | en_HK |
dc.identifier.epage | 15981 | en_HK |
dc.identifier.isi | WOS:000225697000028 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Chen, F=14070141300 | en_HK |
dc.identifier.scopusauthorid | Zhu, NY=7201449530 | en_HK |
dc.identifier.scopusauthorid | Yang, D=7404800756 | en_HK |
dc.identifier.issnl | 0002-7863 | - |