File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Formation of molecular radical cations of enkephalin derivatives via collision-induced dissociation of electrospray-generated copper (II) complex ions of amines and peptides

TitleFormation of molecular radical cations of enkephalin derivatives via collision-induced dissociation of electrospray-generated copper (II) complex ions of amines and peptides
Authors
Issue Date2001
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jasms
Citation
Journal Of The American Society For Mass Spectrometry, 2001, v. 12 n. 10, p. 1114-1119 How to Cite?
AbstractFragmentation of some electrospray-generated complex ions, [ 63Cu II(amine)M] ·2+, where M is an enkephalin derivative, produces the radical cation of the peptide, M ·+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M ·+ ion yields a prominent [M - 106] ·+ product ion for tyrosine-containing peptides, and a prominent [M - 129] ·+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed. Copyright © 2001 American Society for Mass Spectrometry.
Persistent Identifierhttp://hdl.handle.net/10722/167690
ISSN
2015 Impact Factor: 3.031
2015 SCImago Journal Rankings: 1.322
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChu, IKen_US
dc.contributor.authorRodriguez, CFen_US
dc.contributor.authorHopkinson, ACen_US
dc.contributor.authorSiu, KWMen_US
dc.contributor.authorLau, TCen_US
dc.date.accessioned2012-10-08T03:10:04Z-
dc.date.available2012-10-08T03:10:04Z-
dc.date.issued2001en_US
dc.identifier.citationJournal Of The American Society For Mass Spectrometry, 2001, v. 12 n. 10, p. 1114-1119en_US
dc.identifier.issn1044-0305en_US
dc.identifier.urihttp://hdl.handle.net/10722/167690-
dc.description.abstractFragmentation of some electrospray-generated complex ions, [ 63Cu II(amine)M] ·2+, where M is an enkephalin derivative, produces the radical cation of the peptide, M ·+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M ·+ ion yields a prominent [M - 106] ·+ product ion for tyrosine-containing peptides, and a prominent [M - 129] ·+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed. Copyright © 2001 American Society for Mass Spectrometry.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jasmsen_US
dc.relation.ispartofJournal of the American Society for Mass Spectrometryen_US
dc.subject.meshAmines - Chemistryen_US
dc.subject.meshCopper - Chemistryen_US
dc.subject.meshEnkephalins - Chemistryen_US
dc.subject.meshIndicators And Reagentsen_US
dc.subject.meshOligopeptides - Chemistryen_US
dc.subject.meshSpectrometry, Mass, Electrospray Ionizationen_US
dc.titleFormation of molecular radical cations of enkephalin derivatives via collision-induced dissociation of electrospray-generated copper (II) complex ions of amines and peptidesen_US
dc.typeArticleen_US
dc.identifier.emailChu, IK:ivankchu@hku.hken_US
dc.identifier.authorityChu, IK=rp00683en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S1044-0305(01)00297-5en_US
dc.identifier.pmid11605973-
dc.identifier.scopuseid_2-s2.0-0035567108en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035567108&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue10en_US
dc.identifier.spage1114en_US
dc.identifier.epage1119en_US
dc.identifier.isiWOS:000171469800007-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChu, IK=7103327484en_US
dc.identifier.scopusauthoridRodriguez, CF=13305010900en_US
dc.identifier.scopusauthoridHopkinson, AC=15067169300en_US
dc.identifier.scopusauthoridSiu, KWM=35312218500en_US
dc.identifier.scopusauthoridLau, TC=7102222310en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats