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Article: A novel, view-independent method for strain mapping in myocardial elastography: Eliminating angle and centroid dependence

TitleA novel, view-independent method for strain mapping in myocardial elastography: Eliminating angle and centroid dependence
Authors
Issue Date2007
PublisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/pmb
Citation
Physics In Medicine And Biology, 2007, v. 52 n. 14, p. 4063-4080 How to Cite?
AbstractRobust indices of regional and global cardiac function are a key factor in detection and treatment of heart disease as well as understanding of the fundamental mechanisms of a healthy heart. Myocardial elastography provides a noninvasive method for imaging and measuring displacement and strain of the myocardium for the early detection of cardiovascular disease. However, two-dimensional in-plane axial and lateral strains measured depend on the sonographic view used. This becomes especially critical in a clinical setting and may induce large variations in the measured strains, potentially leading to false diagnoses. A novel method in myocardial elastography is proposed for eliminating this view dependence by deriving the polar, principal and classified principal strains. The performance of the proposed methodology is assessed by employing 3D finite-element left-ventricular models of a control and an ischemic canine heart. Although polar strains are angle-independent, they are sensitive to the selected reference coordinate system, which requires the definition of a centroid of the left ventricle (LV). In contrast, principal strains derived through eigenvalue decomposition exhibit the inherent characteristic of coordinate system independence, offering view (i.e., angle and centroid)-independent strain measurements. Classified principal strains are obtained by assigning the principal components in the physical ventricular coordinate system. An extensive strain analysis illustrates the improvement in interpretation and visualization of the full-field myocardial deformation by using the classified principal strains, clearly depicting the ischemic and non-ischemic regions. Strain maps, independent of sonographic views and imaging planes, that can be used to accurately detect regional contractile dysfunction are demonstrated. © 2007 IOP Publishing Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/167054
ISSN
2015 Impact Factor: 2.811
2015 SCImago Journal Rankings: 1.577
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZervantonakis, IKen_US
dc.contributor.authorFungKeeFung, SDen_US
dc.contributor.authorLee, WNen_US
dc.contributor.authorKonofagou, EEen_US
dc.date.accessioned2012-09-28T04:02:23Z-
dc.date.available2012-09-28T04:02:23Z-
dc.date.issued2007en_US
dc.identifier.citationPhysics In Medicine And Biology, 2007, v. 52 n. 14, p. 4063-4080en_US
dc.identifier.issn0031-9155en_US
dc.identifier.urihttp://hdl.handle.net/10722/167054-
dc.description.abstractRobust indices of regional and global cardiac function are a key factor in detection and treatment of heart disease as well as understanding of the fundamental mechanisms of a healthy heart. Myocardial elastography provides a noninvasive method for imaging and measuring displacement and strain of the myocardium for the early detection of cardiovascular disease. However, two-dimensional in-plane axial and lateral strains measured depend on the sonographic view used. This becomes especially critical in a clinical setting and may induce large variations in the measured strains, potentially leading to false diagnoses. A novel method in myocardial elastography is proposed for eliminating this view dependence by deriving the polar, principal and classified principal strains. The performance of the proposed methodology is assessed by employing 3D finite-element left-ventricular models of a control and an ischemic canine heart. Although polar strains are angle-independent, they are sensitive to the selected reference coordinate system, which requires the definition of a centroid of the left ventricle (LV). In contrast, principal strains derived through eigenvalue decomposition exhibit the inherent characteristic of coordinate system independence, offering view (i.e., angle and centroid)-independent strain measurements. Classified principal strains are obtained by assigning the principal components in the physical ventricular coordinate system. An extensive strain analysis illustrates the improvement in interpretation and visualization of the full-field myocardial deformation by using the classified principal strains, clearly depicting the ischemic and non-ischemic regions. Strain maps, independent of sonographic views and imaging planes, that can be used to accurately detect regional contractile dysfunction are demonstrated. © 2007 IOP Publishing Ltd.en_US
dc.languageengen_US
dc.publisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/pmben_US
dc.relation.ispartofPhysics in Medicine and Biologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshComputer Simulationen_US
dc.subject.meshDiagnostic Imaging - Methodsen_US
dc.subject.meshDogsen_US
dc.subject.meshElasticityen_US
dc.subject.meshHeart - Physiopathologyen_US
dc.subject.meshImage Interpretation, Computer-Assisted - Methodsen_US
dc.subject.meshModels, Cardiovascularen_US
dc.subject.meshMyocardial Ischemia - Diagnosis - Physiopathologyen_US
dc.titleA novel, view-independent method for strain mapping in myocardial elastography: Eliminating angle and centroid dependenceen_US
dc.typeArticleen_US
dc.identifier.emailLee, WN: wnlee@hku.hken_US
dc.identifier.authorityLee, WN=rp01663en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1088/0031-9155/52/14/004en_US
dc.identifier.pmid17664595-
dc.identifier.scopuseid_2-s2.0-34547247614en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34547247614&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume52en_US
dc.identifier.issue14en_US
dc.identifier.spage4063en_US
dc.identifier.epage4080en_US
dc.identifier.isiWOS:000247400000004-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridZervantonakis, IK=32267767400en_US
dc.identifier.scopusauthoridFungKeeFung, SD=14919178600en_US
dc.identifier.scopusauthoridLee, WN=22634980600en_US
dc.identifier.scopusauthoridKonofagou, EE=7005877325en_US
dc.identifier.citeulike4017737-

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