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Conference Paper: Developing a photochemically cross-linked collagen plug to solve the cell leakage problem for intradiscal injection of mesenchymal stem cells (Mscs): a pilot study

TitleDeveloping a photochemically cross-linked collagen plug to solve the cell leakage problem for intradiscal injection of mesenchymal stem cells (Mscs): a pilot study
Authors
Issue Date2012
PublisherGeorg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53
Citation
The World Forum for Spine Research (WFSR 2012): The Intervertebral Disc - from Degeneration to Pain, Helsinki, Finland, 18-21 June 2012. In Global Spine Journal, 2012, v. 2 n. S1, no. P117 How to Cite?
AbstractINTRODUCTION: Stem cells possess great potential in treating disk degeneration. MSC is the most clinically relevant cell source but its functional outcomes are still far from satisfaction. One of the primary reasons for the suboptimal performance of MSCs is that the majority of injected cells leaked out from the injection path. Existing attempts addressing this issue focus on further increasing the viscosity of carrier and use of BioGlue. Nevertheless, from others and our own experiences, the high intradiscal pressure in the IVD would extrude the injected cells out immediately even with solid carriers while the blocking effect of glues is only transient as large osteophyte structure was still seen in 6 mon...
Persistent Identifierhttp://hdl.handle.net/10722/166920
ISSN
2015 SCImago Journal Rankings: 0.108

 

DC FieldValueLanguage
dc.contributor.authorChik, TKen_US
dc.contributor.authorChoy, THen_US
dc.contributor.authorTeng, WKen_US
dc.contributor.authorMa, XYen_US
dc.contributor.authorLi, YYen_US
dc.contributor.authorLeung, VYLen_US
dc.contributor.authorCheung, KMCen_US
dc.contributor.authorChan, BPen_US
dc.date.accessioned2012-09-21T01:43:36Z-
dc.date.available2012-09-21T01:43:36Z-
dc.date.issued2012en_US
dc.identifier.citationThe World Forum for Spine Research (WFSR 2012): The Intervertebral Disc - from Degeneration to Pain, Helsinki, Finland, 18-21 June 2012. In Global Spine Journal, 2012, v. 2 n. S1, no. P117en_US
dc.identifier.issn2192-5682-
dc.identifier.urihttp://hdl.handle.net/10722/166920-
dc.description.abstractINTRODUCTION: Stem cells possess great potential in treating disk degeneration. MSC is the most clinically relevant cell source but its functional outcomes are still far from satisfaction. One of the primary reasons for the suboptimal performance of MSCs is that the majority of injected cells leaked out from the injection path. Existing attempts addressing this issue focus on further increasing the viscosity of carrier and use of BioGlue. Nevertheless, from others and our own experiences, the high intradiscal pressure in the IVD would extrude the injected cells out immediately even with solid carriers while the blocking effect of glues is only transient as large osteophyte structure was still seen in 6 mon...-
dc.languageengen_US
dc.publisherGeorg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53-
dc.relation.ispartofGlobal Spine Journalen_US
dc.rightsGlobal Spine Journal. Copyright © Georg Thieme Verlag.-
dc.titleDeveloping a photochemically cross-linked collagen plug to solve the cell leakage problem for intradiscal injection of mesenchymal stem cells (Mscs): a pilot studyen_US
dc.typeConference_Paperen_US
dc.identifier.emailChik, TK: tkchik@hku.hken_US
dc.identifier.emailChoy, TH: thandrew@hku.hken_US
dc.identifier.emailTeng, WK: tengwaikeng@yahoo.comen_US
dc.identifier.emailLi, YY: licyy@hkucc.hku.hken_US
dc.identifier.emailLeung, VYL: vicleung@hku.hken_US
dc.identifier.emailCheung, KMC: cheungmc@hku.hk-
dc.identifier.emailChan, BP: bpchan@hkucc.hku.hk-
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.identifier.authorityChan, BP=rp00087en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1055/s-0032-1319986-
dc.identifier.hkuros211316en_US
dc.identifier.volume2-
dc.identifier.issueS1-
dc.publisher.placeGermany-
dc.customcontrol.immutablesml 130320-

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