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Conference Paper: Intradiscal delivery of mesenchymal stem cells in collagen microspheres in a rabbit disc degeneration model: a preliminary study

TitleIntradiscal delivery of mesenchymal stem cells in collagen microspheres in a rabbit disc degeneration model: a preliminary study
Authors
Issue Date2012
PublisherGeorg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53
Citation
The World Forum for Spine Research (WFSR 2012): The Intervertebral Disc - from Degeneration to Pain, Helsinki, Finland, 18-21 June 2012. In Global Spine Journal, 2012, v. 2 n. S1, no. P113 How to Cite?
AbstractINTRODUCTION: Degeneration of intervertebral disk (IVD) has been characterized by the breakdown of the extracellular matrix and loss of water content and proteoglycan. Mesenchymal stem cells (MSCs) have been demonstrated as a promising cell source in disk regeneration. Injectable biomaterials as MSCs carriers allow needle-guided graft delivery to minimize trauma of the disc, and thus are preferable for IVD engineering. Our lab has developed a microencapsulation platform to make injectable solid microspheres entrapping cells in fiber meshwork of different extracellular matrices for scaffolding or cell delivery. As a first attempt, this study aims to compare the efficacy of injecting MSCs entrapped in collagen micro...
Persistent Identifierhttp://hdl.handle.net/10722/166919
ISSN
2015 SCImago Journal Rankings: 0.108

 

DC FieldValueLanguage
dc.contributor.authorLi, YYen_US
dc.contributor.authorDiao, Hen_US
dc.contributor.authorChow, STen_US
dc.contributor.authorLeung, VYLen_US
dc.contributor.authorCheung, KMCen_US
dc.contributor.authorChan, BPen_US
dc.date.accessioned2012-09-21T01:43:35Z-
dc.date.available2012-09-21T01:43:35Z-
dc.date.issued2012en_US
dc.identifier.citationThe World Forum for Spine Research (WFSR 2012): The Intervertebral Disc - from Degeneration to Pain, Helsinki, Finland, 18-21 June 2012. In Global Spine Journal, 2012, v. 2 n. S1, no. P113en_US
dc.identifier.issn2192-5682-
dc.identifier.urihttp://hdl.handle.net/10722/166919-
dc.description.abstractINTRODUCTION: Degeneration of intervertebral disk (IVD) has been characterized by the breakdown of the extracellular matrix and loss of water content and proteoglycan. Mesenchymal stem cells (MSCs) have been demonstrated as a promising cell source in disk regeneration. Injectable biomaterials as MSCs carriers allow needle-guided graft delivery to minimize trauma of the disc, and thus are preferable for IVD engineering. Our lab has developed a microencapsulation platform to make injectable solid microspheres entrapping cells in fiber meshwork of different extracellular matrices for scaffolding or cell delivery. As a first attempt, this study aims to compare the efficacy of injecting MSCs entrapped in collagen micro...-
dc.languageengen_US
dc.publisherGeorg Thieme Verlag. The Journal's web site is located at http://www.thieme.com/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=1351&category_id=90&option=com_virtuemart&Itemid=53-
dc.relation.ispartofGlobal Spine Journalen_US
dc.rightsGlobal Spine Journal. Copyright © Georg Thieme Verlag.-
dc.titleIntradiscal delivery of mesenchymal stem cells in collagen microspheres in a rabbit disc degeneration model: a preliminary studyen_US
dc.typeConference_Paperen_US
dc.identifier.emailLi, YY: licyy@hkucc.hku.hken_US
dc.identifier.emailDiao, H: huajia@hku.hken_US
dc.identifier.emailChow, ST: chowst@hku.hken_US
dc.identifier.emailLeung, VYL: vicleung@hku.hken_US
dc.identifier.emailCheung, KMC: cheungmc@hku.hken_US
dc.identifier.emailChan, BP: bpchan@hkucc.hku.hken_US
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.identifier.authorityChan, BP=rp00087en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1055/s-0032-1319982-
dc.identifier.hkuros211313en_US
dc.identifier.volume2-
dc.identifier.issueS1-
dc.publisher.placeGermany-
dc.customcontrol.immutablesml 130320-

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