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Conference Paper: Infective keratitis in Hong Kong

TitleInfective keratitis in Hong Kong
Authors
Issue Date2012
PublisherESCRS
Citation
The 30th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS 2012), Milan, Italy, 8-12 September 2012. How to Cite?
Abstract
PURPOSE: To report the prevalence of infective keratitis in Hong Kong over a 7-year period, and to study the pattern of antibiotic resistance among these cases. SETTING: Eye Clinic, Eye Institute, University of Hong Kong METHODS: A retrospective review. All medical records of patients undergoing corneal scrapping from 1/1/2004 to 31/8/2011, at the Eye Clinic of the Eye Institute, University of Hong Kong, were reviewed. Culture result and sensitivity were analyzed. RESULTS: Corneal scrapping was performed on 306 patients during the period reviewed. Among them, 131 were male (48.3%). Mean age was 39 years old (range 1 to 96). Culture was positive in 82 cases (26.8%). Among the culture positive cases, the three most common pathogens were coagulase negative staphylococcus (9.5%), Pseudomonas Aeruginosa (6.9%), and Staphylococcus Aureus (4.6%). Among all culture positive cases with pathogens identified, resistance was noted towards methicillin (85%), penicillin (78%), cefuroxime (48%), erythromycin (34%), ciprofloxacin (20%), tobramycin (18%), and amikacin (14%). Fortunately, all were sensitive to gentamicin (100%) and vancomycin (100%). CONCLUSIONS: Culture positive rate for infective keratitis in Hong Kong is compatible to that reported in the literature. Common causative pathogens and respective sensitivity reported. Common empirical antibiotics for infective keratitis as well as prophylaxis for post-cataract surgery antimicrobial coverage included ciprofloxacin, levofloxacin, and tobramycin. Gentamicin, although being a first-line agent, appeared to have a high sensitivity rate. In view of the resistant pattern, empirical antibiotic of choice should be amended.
DescriptionPoster
Persistent Identifierhttp://hdl.handle.net/10722/166821

 

DC FieldValueLanguage
dc.contributor.authorWong, Ien_US
dc.contributor.authorChan, K-
dc.date.accessioned2012-09-20T08:50:23Z-
dc.date.available2012-09-20T08:50:23Z-
dc.date.issued2012en_US
dc.identifier.citationThe 30th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS 2012), Milan, Italy, 8-12 September 2012.en_US
dc.identifier.urihttp://hdl.handle.net/10722/166821-
dc.descriptionPoster-
dc.description.abstractPURPOSE: To report the prevalence of infective keratitis in Hong Kong over a 7-year period, and to study the pattern of antibiotic resistance among these cases. SETTING: Eye Clinic, Eye Institute, University of Hong Kong METHODS: A retrospective review. All medical records of patients undergoing corneal scrapping from 1/1/2004 to 31/8/2011, at the Eye Clinic of the Eye Institute, University of Hong Kong, were reviewed. Culture result and sensitivity were analyzed. RESULTS: Corneal scrapping was performed on 306 patients during the period reviewed. Among them, 131 were male (48.3%). Mean age was 39 years old (range 1 to 96). Culture was positive in 82 cases (26.8%). Among the culture positive cases, the three most common pathogens were coagulase negative staphylococcus (9.5%), Pseudomonas Aeruginosa (6.9%), and Staphylococcus Aureus (4.6%). Among all culture positive cases with pathogens identified, resistance was noted towards methicillin (85%), penicillin (78%), cefuroxime (48%), erythromycin (34%), ciprofloxacin (20%), tobramycin (18%), and amikacin (14%). Fortunately, all were sensitive to gentamicin (100%) and vancomycin (100%). CONCLUSIONS: Culture positive rate for infective keratitis in Hong Kong is compatible to that reported in the literature. Common causative pathogens and respective sensitivity reported. Common empirical antibiotics for infective keratitis as well as prophylaxis for post-cataract surgery antimicrobial coverage included ciprofloxacin, levofloxacin, and tobramycin. Gentamicin, although being a first-line agent, appeared to have a high sensitivity rate. In view of the resistant pattern, empirical antibiotic of choice should be amended.-
dc.languageengen_US
dc.publisherESCRS-
dc.relation.ispartof30th ESCRS Congress 2012en_US
dc.titleInfective keratitis in Hong Kongen_US
dc.typeConference_Paperen_US
dc.identifier.emailWong, I: wongyhi@hku.hken_US
dc.identifier.authorityWong, I=rp01467en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros207471en_US
dc.identifier.hkuros216706-
dc.publisher.placeIreland-

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