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Conference Paper: Intervertebral disc degeneration on MRI is associated with low back pain: a population-based study

TitleIntervertebral disc degeneration on MRI is associated with low back pain: a population-based study
Authors
Issue Date2011
PublisherSICOT 2011.
Citation
The 25th Triennial World Congress (SICOT 2011), Prague, Czech Republic, 6-9 September 2011. In Abstract Book of SICOT 2011 How to Cite?
AbstractINTRODUCTION: The presence of disc degeneration based on MRI and its association with low back pain (LBP) remains under heated debate. As part of the largest radiographic and clinical population-based study of the lumbar spine, this study addressed the association of disc degeneration as noted on MRI with the presence and severity of LBP. METHODS: Sagittal T2-weighted MRIs of the lumbar spine were obtained of 2,702 adult individuals of Southern Chinese origin. The presence and severity of lumbar disc degeneration was assessed. An overall degenerative disc disease (DDD) score (range: 0 to 15) was obtained. Additional assessment of spine pathology/abnormalities, LBP, VAS pain scores, and subject demographics were performed. RESULTS: There were 1,614 females and 1,088 males (mean age=42 years). Individuals with disc degeneration had a higher prevalence of LBP (p<0.001). VAS pain scores were significantly higher in individuals with disc degeneration (p<0.001). DDD scores were significantly greater in individuals with LBP (p<0.001). Logistic regression modeling noted a significant quadratic trend (r2=0.95) increased association of disc degeneration severity and LBP (p<0.001). CONCLUSION: This large-scale study noted that disc degeneration based on MRI is significantly associated with LBP. The “global severity” of disc degeneration was found to increase the risk of having LBP. These findings support that the study of disc degeneration on MRI is clinically relevant, and that treatment strategies, such as biological therapies, that can reduce degeneration can also diminish the incidence of LBP.
DescriptionFree Papers: Spine - Lumbar: abstract no. 29657
Persistent Identifierhttp://hdl.handle.net/10722/165521

 

DC FieldValueLanguage
dc.contributor.authorSamartzis, Den_US
dc.contributor.authorKarppinen, Jen_US
dc.contributor.authorLuk, Ken_US
dc.contributor.authorCheung, Ken_US
dc.date.accessioned2012-09-20T08:19:19Z-
dc.date.available2012-09-20T08:19:19Z-
dc.date.issued2011en_US
dc.identifier.citationThe 25th Triennial World Congress (SICOT 2011), Prague, Czech Republic, 6-9 September 2011. In Abstract Book of SICOT 2011en_US
dc.identifier.urihttp://hdl.handle.net/10722/165521-
dc.descriptionFree Papers: Spine - Lumbar: abstract no. 29657-
dc.description.abstractINTRODUCTION: The presence of disc degeneration based on MRI and its association with low back pain (LBP) remains under heated debate. As part of the largest radiographic and clinical population-based study of the lumbar spine, this study addressed the association of disc degeneration as noted on MRI with the presence and severity of LBP. METHODS: Sagittal T2-weighted MRIs of the lumbar spine were obtained of 2,702 adult individuals of Southern Chinese origin. The presence and severity of lumbar disc degeneration was assessed. An overall degenerative disc disease (DDD) score (range: 0 to 15) was obtained. Additional assessment of spine pathology/abnormalities, LBP, VAS pain scores, and subject demographics were performed. RESULTS: There were 1,614 females and 1,088 males (mean age=42 years). Individuals with disc degeneration had a higher prevalence of LBP (p<0.001). VAS pain scores were significantly higher in individuals with disc degeneration (p<0.001). DDD scores were significantly greater in individuals with LBP (p<0.001). Logistic regression modeling noted a significant quadratic trend (r2=0.95) increased association of disc degeneration severity and LBP (p<0.001). CONCLUSION: This large-scale study noted that disc degeneration based on MRI is significantly associated with LBP. The “global severity” of disc degeneration was found to increase the risk of having LBP. These findings support that the study of disc degeneration on MRI is clinically relevant, and that treatment strategies, such as biological therapies, that can reduce degeneration can also diminish the incidence of LBP.-
dc.languageengen_US
dc.publisherSICOT 2011.-
dc.relation.ispartof25th Triennial World Congress, SICOT 2011en_US
dc.titleIntervertebral disc degeneration on MRI is associated with low back pain: a population-based studyen_US
dc.typeConference_Paperen_US
dc.identifier.emailSamartzis, D: dspine@hku.hken_US
dc.identifier.emailLuk, K: hcm21000@hku.hken_US
dc.identifier.emailCheung, K: cheungmc@hku.hken_US
dc.identifier.authoritySamartzis, D=rp01430en_US
dc.identifier.authorityLuk, K=rp00333en_US
dc.identifier.authorityCheung, K=rp00387en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros208426en_US
dc.identifier.hkuros209824-
dc.identifier.hkuros255992-
dc.customcontrol.immutablesml 130514 ; 151118 - merged-

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