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Conference Paper: The genetic landscape of immune-competent and HIV lymphoma

TitleThe genetic landscape of immune-competent and HIV lymphoma
Authors
Issue Date2011
PublisherBioMed Central. The Journal's web site is located at http://www.infectagentscancer.com/home
Citation
The 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1 How to Cite?
Abstract
Burkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) are aggressive forms of lymphoma in adults and demonstrate overlapping morphology, immunophenotype and clinical behavior. The risk of developing these tumors increases ten to hundred-fold in the setting of HIV infection. The genetic causes and the role of specific mutations, especially in the setting of HIV, are largely unknown. The decoding of the human genome and the advent of high-throughput sequencing have provided rich opportunities for the comprehensive identification of the genetic causes of cancer. In order to comprehensively identify genes that are recurrently mutated in immune-competent DLBCL and BL, we obtained a total of 92 cases of DLBCLs and 40 cases of BL. These cases were compared to a set of 5 DLBCLs and BL tumors derived from patients with HIV. The DLBCL cases were divided into a discovery set (N=34) and …
DescriptionThis journal supplement is Proceedings of the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI)
Persistent Identifierhttp://hdl.handle.net/10722/165453
ISSN
2013 Impact Factor: 2.071
2013 SCImago Journal Rankings: 0.824
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorZhang, Jen_US
dc.contributor.authorGrubor, Ven_US
dc.contributor.authorLove, CLen_US
dc.contributor.authorBanerjee, Aen_US
dc.contributor.authorRichards, KLen_US
dc.contributor.authorMiezcowski, Pen_US
dc.contributor.authorDunphy, CHen_US
dc.contributor.authorChoi, WWLen_US
dc.contributor.authorAu, WYen_US
dc.contributor.authorSrivastava, Gen_US
dc.contributor.authorLugar, PLen_US
dc.contributor.authorRizzieri, DAen_US
dc.contributor.authorLagoo, ASen_US
dc.contributor.authorBernal-Mizrachi, Len_US
dc.contributor.authorMann, KPen_US
dc.contributor.authorFlowers, CRen_US
dc.contributor.authorNaresh, KNen_US
dc.contributor.authorEvens, AMen_US
dc.contributor.authorGordon, LIen_US
dc.contributor.authorCzader, MBen_US
dc.contributor.authorGill, JIen_US
dc.contributor.authorHsi, EDen_US
dc.contributor.authorLiu, Qen_US
dc.contributor.authorFan, Aen_US
dc.contributor.authorWalsh, Ken_US
dc.contributor.authorJima, DDen_US
dc.contributor.authorLuftig, Men_US
dc.contributor.authorNi, Ten_US
dc.contributor.authorZhu, Jen_US
dc.contributor.authorChadburn, Aen_US
dc.contributor.authorLevy, Sen_US
dc.contributor.authorDunson, DBen_US
dc.contributor.authorDave, SSen_US
dc.date.accessioned2012-09-20T08:18:20Z-
dc.date.available2012-09-20T08:18:20Z-
dc.date.issued2011en_US
dc.identifier.citationThe 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1en_US
dc.identifier.issn1750-9378-
dc.identifier.urihttp://hdl.handle.net/10722/165453-
dc.descriptionThis journal supplement is Proceedings of the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI)-
dc.descriptionOpen Access Journal-
dc.description.abstractBurkitt lymphoma (BL) and diffuse large B cell lymphoma (DLBCL) are aggressive forms of lymphoma in adults and demonstrate overlapping morphology, immunophenotype and clinical behavior. The risk of developing these tumors increases ten to hundred-fold in the setting of HIV infection. The genetic causes and the role of specific mutations, especially in the setting of HIV, are largely unknown. The decoding of the human genome and the advent of high-throughput sequencing have provided rich opportunities for the comprehensive identification of the genetic causes of cancer. In order to comprehensively identify genes that are recurrently mutated in immune-competent DLBCL and BL, we obtained a total of 92 cases of DLBCLs and 40 cases of BL. These cases were compared to a set of 5 DLBCLs and BL tumors derived from patients with HIV. The DLBCL cases were divided into a discovery set (N=34) and …-
dc.languageengen_US
dc.publisherBioMed Central. The Journal's web site is located at http://www.infectagentscancer.com/home-
dc.relation.ispartofInfectious Agents and Canceren_US
dc.rightsInfectious Agents and Cancer. Copyright © BioMed Central.-
dc.titleThe genetic landscape of immune-competent and HIV lymphomaen_US
dc.typeConference_Paperen_US
dc.identifier.emailChoi, WWL: choiwl@hkucc.hku.hken_US
dc.identifier.emailAu, WY: auwing@hkucc.hku.hken_US
dc.identifier.emailSrivastava, G: sgopesh@hkucc.hku.hken_US
dc.identifier.authorityChoi, WWL=rp00247en_US
dc.identifier.authoritySrivastava, G=rp00365en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1186/1750-9378-7-S1-O1-
dc.identifier.pmcidPMC3330083-
dc.identifier.hkuros210936en_US
dc.identifier.hkuros213480-
dc.identifier.volume7-
dc.identifier.issuesuppl. 1-
dc.publisher.placeUnited Kingdom-
dc.description.otherThe 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICAMAOI), Bethesda, MD., 7-8 November 2011. In Infectious Agents and Cancer, 2011, v. 7 suppl. 1, article no. O1-

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