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Conference Paper: The relationship between waist circumference and glycated hemoglobin in the United States

TitleThe relationship between waist circumference and glycated hemoglobin in the United States
Authors
Issue Date2012
PublisherHong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3
Citation
The 20th Annual Scientific Congress of the Hong Kong College of Cardiology (ASC 2012), Hong Kong, 4-6 May 2012. In Journal of the Hong Kong College of Cardiology, 2012, v. 20 suppl. 1, p. A1, abstract no. 2 How to Cite?
AbstractPURPOSE: Obesity leads to type 2 diabetes, an important risk factor for cardiovascular disease. As glycated hemoglobin (A1C) can now be used for the diagnosis of diabetes, we studied the relationship between A1C and waist circumference. METHODS: 1806 men and 1734 women over the age of 20 years in the United States National Health and Nutrition Examination Survey 2005-2008 who had fasted overnight and were not on medication for diabetes were included for analysis. A1C levels of 5.7% and 6.5% were used as cut-offs for pre-diabetes and diabetes respectively. RESULTS: The waist circumference had a linear association with A1C in both men (P=0.001) and women (P<0.001). An A1C level of 5.7% corresponded to a waist circumference of 98.4, 102.4 and 106.4 cm in men and 96.1, 96.6 and 97.0 cm in women at ages 30, 50 and 70 respectively. An A1C level of 6.5% corresponded to a waist circumference of 101.5, 105.4 and 109.4 cm in men and 103.4, 103.9 and 104.4 cm in women at ages 30, 50 and 70 years respectively. The waist circumference increased significantly with age in men (P<0.001) but only slightly in women. The linear relationship between waist circumference and A1C was seen in all non-Hispanic whites (men, P=0.013; women, P<0.001), non-Hispanic blacks (men, P<0.001; women, P=0.013), and Mexican American women (P=0.001). CONCLUSIONS: A1C level increases linearly with waist circumference. A smaller waist circumference corresponds to a lower A1C level in both men and women. This association is seen among all ethnic groups except Mexican American men. In men, the waist circumferences associated with pre-diabetes and diabetes change with age. Our results reveal that younger American men with a waist circumference below 100 cm are already at risk of pre-diabetes.
DescriptionFree Paper Session - Coronary Artery Disease
Persistent Identifierhttp://hdl.handle.net/10722/165443
ISSN
2015 SCImago Journal Rankings: 0.102

 

DC FieldValueLanguage
dc.contributor.authorSamaranayake, NRen_US
dc.contributor.authorLi, Cen_US
dc.contributor.authorOng, KLen_US
dc.contributor.authorCheung, BMYen_US
dc.date.accessioned2012-09-20T08:18:16Z-
dc.date.available2012-09-20T08:18:16Z-
dc.date.issued2012en_US
dc.identifier.citationThe 20th Annual Scientific Congress of the Hong Kong College of Cardiology (ASC 2012), Hong Kong, 4-6 May 2012. In Journal of the Hong Kong College of Cardiology, 2012, v. 20 suppl. 1, p. A1, abstract no. 2en_US
dc.identifier.issn1027-7811-
dc.identifier.urihttp://hdl.handle.net/10722/165443-
dc.descriptionFree Paper Session - Coronary Artery Disease-
dc.description.abstractPURPOSE: Obesity leads to type 2 diabetes, an important risk factor for cardiovascular disease. As glycated hemoglobin (A1C) can now be used for the diagnosis of diabetes, we studied the relationship between A1C and waist circumference. METHODS: 1806 men and 1734 women over the age of 20 years in the United States National Health and Nutrition Examination Survey 2005-2008 who had fasted overnight and were not on medication for diabetes were included for analysis. A1C levels of 5.7% and 6.5% were used as cut-offs for pre-diabetes and diabetes respectively. RESULTS: The waist circumference had a linear association with A1C in both men (P=0.001) and women (P<0.001). An A1C level of 5.7% corresponded to a waist circumference of 98.4, 102.4 and 106.4 cm in men and 96.1, 96.6 and 97.0 cm in women at ages 30, 50 and 70 respectively. An A1C level of 6.5% corresponded to a waist circumference of 101.5, 105.4 and 109.4 cm in men and 103.4, 103.9 and 104.4 cm in women at ages 30, 50 and 70 years respectively. The waist circumference increased significantly with age in men (P<0.001) but only slightly in women. The linear relationship between waist circumference and A1C was seen in all non-Hispanic whites (men, P=0.013; women, P<0.001), non-Hispanic blacks (men, P<0.001; women, P=0.013), and Mexican American women (P=0.001). CONCLUSIONS: A1C level increases linearly with waist circumference. A smaller waist circumference corresponds to a lower A1C level in both men and women. This association is seen among all ethnic groups except Mexican American men. In men, the waist circumferences associated with pre-diabetes and diabetes change with age. Our results reveal that younger American men with a waist circumference below 100 cm are already at risk of pre-diabetes.-
dc.languageengen_US
dc.publisherHong Kong College of Cardiology. The Journal's web site is located at http://www.hkcchk.com/journals.php#3-
dc.relation.ispartofJournal of the Hong Kong College of Cardiologyen_US
dc.titleThe relationship between waist circumference and glycated hemoglobin in the United Statesen_US
dc.typeConference_Paperen_US
dc.identifier.emailSamaranayake, NR: h1094072@hku.hken_US
dc.identifier.emailLi, C: dcli@hku.hk-
dc.identifier.emailOng, KL: okl2000@hku.hk-
dc.identifier.emailCheung, BMY: mycheung@hku.hk-
dc.identifier.authorityCheung, BMY=rp01321en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros208511en_US
dc.identifier.volume20en_US
dc.identifier.issuesuppl. 1en_US
dc.identifier.spageA1en_US
dc.identifier.epageA1en_US
dc.publisher.placeHong Kong-
dc.description.otherThe 20th Annual Scientific Congress of the Hong Kong College of Cardiology (ASC 2012), Hong Kong, 4-6 May 2012. In Journal of the Hong Kong College of Cardiology, 2012, v. 20 suppl. 1, p. A1, abstract no. 2-

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