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Conference Paper: 1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal rats
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Title1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal rats
 
AuthorsQiao, Z
Cao, P
Wang, AM
Xie, VB
Fan, S
Wu, EX
 
Issue Date2012
 
PublisherInternational Society of Magnetic Resonance in Medicine.
 
CitationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062 [How to Cite?]
 
AbstractIn this study, we hypothesized that the gradual IMCL storage occurs in skeletal muscle during resting, and such storage at resting state would alter in obesity. Specifically, we investigated the IMCL storage at resting state in obese rats by quantifying the rates of IMCL accumulation using continuous and dynamic 1H-MRS. We demonstrated that dynamic 1H-MRS could quantify the IMCL accumulation at resting state in individual muscles. Our preliminary results revealed that the disorder of lipid metabolism in obesity is associated with not only an increased IMCL content, but also the alterations in the rates of IMCL storage at resting state in both slow-oxidative muscle and fast-oxidative glycolytic muscles.
 
DescriptionTheme: Adapting MR in a Changing World
Oral Presentation - Session 06: MRS of Disease, Injury & Pathology in the Body & MSK: no. 0062
 
DC FieldValue
dc.contributor.authorQiao, Z
 
dc.contributor.authorCao, P
 
dc.contributor.authorWang, AM
 
dc.contributor.authorXie, VB
 
dc.contributor.authorFan, S
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2012-09-20T08:16:15Z
 
dc.date.available2012-09-20T08:16:15Z
 
dc.date.issued2012
 
dc.description.abstractIn this study, we hypothesized that the gradual IMCL storage occurs in skeletal muscle during resting, and such storage at resting state would alter in obesity. Specifically, we investigated the IMCL storage at resting state in obese rats by quantifying the rates of IMCL accumulation using continuous and dynamic 1H-MRS. We demonstrated that dynamic 1H-MRS could quantify the IMCL accumulation at resting state in individual muscles. Our preliminary results revealed that the disorder of lipid metabolism in obesity is associated with not only an increased IMCL content, but also the alterations in the rates of IMCL storage at resting state in both slow-oxidative muscle and fast-oxidative glycolytic muscles.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionTheme: Adapting MR in a Changing World
 
dc.descriptionOral Presentation - Session 06: MRS of Disease, Injury & Pathology in the Body & MSK: no. 0062
 
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062
 
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062 [How to Cite?]
 
dc.identifier.hkuros207500
 
dc.identifier.urihttp://hdl.handle.net/10722/165206
 
dc.languageeng
 
dc.publisherInternational Society of Magnetic Resonance in Medicine.
 
dc.publisher.placeAustralia
 
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012
 
dc.title1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal rats
 
dc.typeConference_Paper
 
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<description.abstract>In this study, we hypothesized that the gradual IMCL storage occurs in skeletal muscle during resting, and such storage at resting state would alter in obesity. Specifically, we investigated the IMCL storage at resting state in obese rats by quantifying the rates of IMCL accumulation using continuous and dynamic 1H-MRS. We demonstrated that dynamic 1H-MRS could quantify the IMCL accumulation at resting state in individual muscles. Our preliminary results revealed that the disorder of lipid metabolism in obesity is associated with not only an increased IMCL content, but also the alterations in the rates of IMCL storage at resting state in both slow-oxidative muscle and fast-oxidative glycolytic muscles.</description.abstract>
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