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Conference Paper: 1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal rats

Title1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal rats
Authors
Issue Date2012
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062 How to Cite?
Abstract
In this study, we hypothesized that the gradual IMCL storage occurs in skeletal muscle during resting, and such storage at resting state would alter in obesity. Specifically, we investigated the IMCL storage at resting state in obese rats by quantifying the rates of IMCL accumulation using continuous and dynamic 1H-MRS. We demonstrated that dynamic 1H-MRS could quantify the IMCL accumulation at resting state in individual muscles. Our preliminary results revealed that the disorder of lipid metabolism in obesity is associated with not only an increased IMCL content, but also the alterations in the rates of IMCL storage at resting state in both slow-oxidative muscle and fast-oxidative glycolytic muscles.
DescriptionTheme: Adapting MR in a Changing World
Persistent Identifierhttp://hdl.handle.net/10722/165206

 

DC FieldValueLanguage
dc.contributor.authorQiao, Zen_US
dc.contributor.authorCao, Pen_US
dc.contributor.authorWang, AMen_US
dc.contributor.authorXie, VBen_US
dc.contributor.authorFan, Sen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2012-09-20T08:16:15Z-
dc.date.available2012-09-20T08:16:15Z-
dc.date.issued2012en_US
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062en_US
dc.identifier.urihttp://hdl.handle.net/10722/165206-
dc.descriptionTheme: Adapting MR in a Changing World-
dc.descriptionOral Presentation - Session 06: MRS of Disease, Injury & Pathology in the Body & MSK: no. 0062-
dc.description.abstractIn this study, we hypothesized that the gradual IMCL storage occurs in skeletal muscle during resting, and such storage at resting state would alter in obesity. Specifically, we investigated the IMCL storage at resting state in obese rats by quantifying the rates of IMCL accumulation using continuous and dynamic 1H-MRS. We demonstrated that dynamic 1H-MRS could quantify the IMCL accumulation at resting state in individual muscles. Our preliminary results revealed that the disorder of lipid metabolism in obesity is associated with not only an increased IMCL content, but also the alterations in the rates of IMCL storage at resting state in both slow-oxidative muscle and fast-oxidative glycolytic muscles.-
dc.languageengen_US
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012en_US
dc.title1H-MRS investigation of IMCL storage during resting in skeletal muscle: obese versus normal ratsen_US
dc.typeConference_Paperen_US
dc.identifier.emailQiao, Z: zwqiao@hku.hken_US
dc.identifier.emailFan, S: fanshj08@hkucc.hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros207500en_US
dc.publisher.placeAustralia-
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0062-

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