Conference Paper: Dynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state
| Title | Dynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state |
|---|---|
| Authors | Qiao, Z Cao, P Zhou, IY Fan, S Cheung, MMH Zhang, JW Wu, EX |
| Issue Date | 2012 |
| Publisher | International Society of Magnetic Resonance in Medicine. |
| Citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 [How to Cite?] |
| Abstract | The relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo. |
| Description | Theme: Adapting MR in a Changing World Oral Presentation - Session 44: Structure & Function of Muscle: no. 0438 |
| dc.contributor.author | Qiao, Z |
|---|---|
| dc.contributor.author | Cao, P |
| dc.contributor.author | Zhou, IY |
| dc.contributor.author | Fan, S |
| dc.contributor.author | Cheung, MMH |
| dc.contributor.author | Zhang, JW |
| dc.contributor.author | Wu, EX |
| dc.date.accessioned | 2012-09-20T08:16:15Z |
| dc.date.available | 2012-09-20T08:16:15Z |
| dc.date.issued | 2012 |
| dc.description.abstract | The relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo. |
| dc.description.nature | link_to_OA_fulltext |
| dc.description | Theme: Adapting MR in a Changing World |
| dc.description | Oral Presentation - Session 44: Structure & Function of Muscle: no. 0438 |
| dc.description.other | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 |
| dc.identifier.citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 [How to Cite?] |
| dc.identifier.hkuros | 207498 |
| dc.identifier.uri | http://hdl.handle.net/10722/165205 |
| dc.language | eng |
| dc.publisher | International Society of Magnetic Resonance in Medicine. |
| dc.publisher.place | Australia |
| dc.relation.ispartof | Proceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012 |
| dc.title | Dynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state |
| dc.type | Conference_Paper |