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Conference Paper: Dynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state
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TitleDynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state
 
AuthorsQiao, Z
Cao, P
Zhou, IY
Fan, S
Cheung, MMH
Zhang, JW
Wu, EX
 
Issue Date2012
 
PublisherInternational Society of Magnetic Resonance in Medicine.
 
CitationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 [How to Cite?]
 
AbstractThe relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo.
 
DescriptionTheme: Adapting MR in a Changing World
Oral Presentation - Session 44: Structure & Function of Muscle: no. 0438
 
DC FieldValue
dc.contributor.authorQiao, Z
 
dc.contributor.authorCao, P
 
dc.contributor.authorZhou, IY
 
dc.contributor.authorFan, S
 
dc.contributor.authorCheung, MMH
 
dc.contributor.authorZhang, JW
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2012-09-20T08:16:15Z
 
dc.date.available2012-09-20T08:16:15Z
 
dc.date.issued2012
 
dc.description.abstractThe relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionTheme: Adapting MR in a Changing World
 
dc.descriptionOral Presentation - Session 44: Structure & Function of Muscle: no. 0438
 
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438
 
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 [How to Cite?]
 
dc.identifier.hkuros207498
 
dc.identifier.urihttp://hdl.handle.net/10722/165205
 
dc.languageeng
 
dc.publisherInternational Society of Magnetic Resonance in Medicine.
 
dc.publisher.placeAustralia
 
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012
 
dc.titleDynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state
 
dc.typeConference_Paper
 
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