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Conference Paper: Dynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state

TitleDynamic 1H-MRS revealed muscle type dependent IMCL storage at resting state
Authors
Issue Date2012
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438 How to Cite?
Abstract
The relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo.
DescriptionTheme: Adapting MR in a Changing World
Persistent Identifierhttp://hdl.handle.net/10722/165205

 

DC FieldValueLanguage
dc.contributor.authorQiao, Zen_US
dc.contributor.authorCao, Pen_US
dc.contributor.authorZhou, IYen_US
dc.contributor.authorFan, Sen_US
dc.contributor.authorCheung, MMHen_US
dc.contributor.authorZhang, JWen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2012-09-20T08:16:15Z-
dc.date.available2012-09-20T08:16:15Z-
dc.date.issued2012en_US
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438en_US
dc.identifier.urihttp://hdl.handle.net/10722/165205-
dc.descriptionTheme: Adapting MR in a Changing World-
dc.descriptionOral Presentation - Session 44: Structure & Function of Muscle: no. 0438-
dc.description.abstractThe relationship between accumulation of intramyocellular lipid (IMCL) in skeletal muscle and insulin resistance is not well understood at present time. IMCL storage in skeletal muscles depends on lipid oxidative capacity and fatty acid flux rate. With dynamic 1H-MRS and creatine as the internal reference, a muscle type dependent IMCL storage at resting state was observed and quantified in this study. Such functional IMCL storage quantified by dynamic 1H-MRS could be used as an indicator for studying and probing the dynamic balance between IMCL synthesis and utilization during lipid metabolism in both animal models and humans in vivo.-
dc.languageengen_US
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012en_US
dc.titleDynamic 1H-MRS revealed muscle type dependent IMCL storage at resting stateen_US
dc.typeConference_Paperen_US
dc.identifier.emailQiao, Z: zwqiao@hku.hken_US
dc.identifier.emailZhou, IY: iriszhou@eee.hku.hk-
dc.identifier.emailFan, S: fanshj08@hkucc.hku.hk-
dc.identifier.emailCheung, MMH: thew@hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros207498en_US
dc.publisher.placeAustralia-
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0438-

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