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Conference Paper: Analysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient
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TitleAnalysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient
 
AuthorsCheung, MMH
Ho, LC
Ding, AY
Lau, C
Wu, EX
 
Issue Date2012
 
PublisherInternational Society of Magnetic Resonance in Medicine.
 
CitationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621 [How to Cite?]
 
AbstractIt has been known that kurtosis measurements are dependent on the diffusion time (Δ), due to restricted diffusion, heterogeneity of diffusion compartments or water exchange over different compartments. In this study, we applied oscillating diffusion gradient to investigate the diffusion time effect to DKI measurements in rat brain tissues in vivo. Mean diffusivity and kurtosis were found to increase and decrease respectively with Δ, indicating increased restriction and microstructure heterogeneity. The Δ dependency may provide insights into the complex cellular properties in normal and diseased neural tissues.
 
DescriptionTheme: Adapting MR in a Changing World
Electronic Poster Session - Diffusion & Perfusion - Connectivity, Networks, & Kurtosis: no. 3621 (computer no. 62)
 
DC FieldValue
dc.contributor.authorCheung, MMH
 
dc.contributor.authorHo, LC
 
dc.contributor.authorDing, AY
 
dc.contributor.authorLau, C
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2012-09-20T08:16:13Z
 
dc.date.available2012-09-20T08:16:13Z
 
dc.date.issued2012
 
dc.description.abstractIt has been known that kurtosis measurements are dependent on the diffusion time (Δ), due to restricted diffusion, heterogeneity of diffusion compartments or water exchange over different compartments. In this study, we applied oscillating diffusion gradient to investigate the diffusion time effect to DKI measurements in rat brain tissues in vivo. Mean diffusivity and kurtosis were found to increase and decrease respectively with Δ, indicating increased restriction and microstructure heterogeneity. The Δ dependency may provide insights into the complex cellular properties in normal and diseased neural tissues.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionTheme: Adapting MR in a Changing World
 
dc.descriptionElectronic Poster Session - Diffusion & Perfusion - Connectivity, Networks, & Kurtosis: no. 3621 (computer no. 62)
 
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621
 
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621 [How to Cite?]
 
dc.identifier.hkuros207492
 
dc.identifier.urihttp://hdl.handle.net/10722/165201
 
dc.languageeng
 
dc.publisherInternational Society of Magnetic Resonance in Medicine.
 
dc.publisher.placeAustralia
 
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012
 
dc.titleAnalysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient
 
dc.typeConference_Paper
 
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<description.abstract>It has been known that kurtosis measurements are dependent on the diffusion time (&#916;), due to restricted diffusion, heterogeneity of diffusion compartments or water exchange over different compartments. In this study, we applied oscillating diffusion gradient to investigate the diffusion time effect to DKI measurements in rat brain tissues in vivo. Mean diffusivity and kurtosis were found to increase and decrease respectively with &#916;, indicating increased restriction and microstructure heterogeneity. The &#916; dependency may provide insights into the complex cellular properties in normal and diseased neural tissues.</description.abstract>
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