Conference Paper: Analysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient
| Title | Analysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient |
|---|---|
| Authors | Cheung, MMH Ho, LC Ding, AY Lau, C Wu, EX |
| Issue Date | 2012 |
| Publisher | International Society of Magnetic Resonance in Medicine. |
| Citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621 [How to Cite?] |
| Abstract | It has been known that kurtosis measurements are dependent on the diffusion time (Δ), due to restricted diffusion, heterogeneity of diffusion compartments or water exchange over different compartments. In this study, we applied oscillating diffusion gradient to investigate the diffusion time effect to DKI measurements in rat brain tissues in vivo. Mean diffusivity and kurtosis were found to increase and decrease respectively with Δ, indicating increased restriction and microstructure heterogeneity. The Δ dependency may provide insights into the complex cellular properties in normal and diseased neural tissues. |
| Description | Theme: Adapting MR in a Changing World Electronic Poster Session - Diffusion & Perfusion - Connectivity, Networks, & Kurtosis: no. 3621 (computer no. 62) |
| dc.contributor.author | Cheung, MMH |
|---|---|
| dc.contributor.author | Ho, LC |
| dc.contributor.author | Ding, AY |
| dc.contributor.author | Lau, C |
| dc.contributor.author | Wu, EX |
| dc.date.accessioned | 2012-09-20T08:16:13Z |
| dc.date.available | 2012-09-20T08:16:13Z |
| dc.date.issued | 2012 |
| dc.description.abstract | It has been known that kurtosis measurements are dependent on the diffusion time (Δ), due to restricted diffusion, heterogeneity of diffusion compartments or water exchange over different compartments. In this study, we applied oscillating diffusion gradient to investigate the diffusion time effect to DKI measurements in rat brain tissues in vivo. Mean diffusivity and kurtosis were found to increase and decrease respectively with Δ, indicating increased restriction and microstructure heterogeneity. The Δ dependency may provide insights into the complex cellular properties in normal and diseased neural tissues. |
| dc.description.nature | link_to_OA_fulltext |
| dc.description | Theme: Adapting MR in a Changing World |
| dc.description | Electronic Poster Session - Diffusion & Perfusion - Connectivity, Networks, & Kurtosis: no. 3621 (computer no. 62) |
| dc.description.other | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621 |
| dc.identifier.citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012. no. 3621 [How to Cite?] |
| dc.identifier.hkuros | 207492 |
| dc.identifier.uri | http://hdl.handle.net/10722/165201 |
| dc.language | eng |
| dc.publisher | International Society of Magnetic Resonance in Medicine. |
| dc.publisher.place | Australia |
| dc.relation.ispartof | Proceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012 |
| dc.title | Analysis of effect of short diffusion time in diffusion kurtosis imaging using oscillating gradient |
| dc.type | Conference_Paper |