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Conference Paper: Effect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarction
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TitleEffect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarction
 
AuthorsWu, Y
Zou, C
Liu, W
Liao, WQ
Wu, EX
 
Issue Date2012
 
PublisherInternational Society of Magnetic Resonance in Medicine.
 
CitationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 1858 [How to Cite?]
 
AbstractThe free Gaussian process of water diffusion assumed in conventional DTI was found to not apply with increase of diffusion strength. In this study, effect of b-value on detecting myocardial structural alteration was assessed in infarcted rabbit models. Non-monoexponential diffusion manner was confirmed in both infarct and control groups. FA and radial diffusivity were found to alter significantly in infarct and/or adjacent regions, and the sensitivity to detect their statistical differences among all the groups were b-value dependent with the greatest total number of statistical significances occurred at b-values of 750 to 2000 s/mm2. The study demonstrated the important effect of diffusion strength on DTI index characterization and emphasized the necessity of optimizing b-value for better monitoring and detecting myocardial structural degradation.
 
DescriptionTheme: Adapting MR in a Changing World
Traditional Poster Session - Diffusion & Perfusion - Body Diffusion: no. 1858
 
DC FieldValue
dc.contributor.authorWu, Y
 
dc.contributor.authorZou, C
 
dc.contributor.authorLiu, W
 
dc.contributor.authorLiao, WQ
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2012-09-20T08:16:12Z
 
dc.date.available2012-09-20T08:16:12Z
 
dc.date.issued2012
 
dc.description.abstractThe free Gaussian process of water diffusion assumed in conventional DTI was found to not apply with increase of diffusion strength. In this study, effect of b-value on detecting myocardial structural alteration was assessed in infarcted rabbit models. Non-monoexponential diffusion manner was confirmed in both infarct and control groups. FA and radial diffusivity were found to alter significantly in infarct and/or adjacent regions, and the sensitivity to detect their statistical differences among all the groups were b-value dependent with the greatest total number of statistical significances occurred at b-values of 750 to 2000 s/mm2. The study demonstrated the important effect of diffusion strength on DTI index characterization and emphasized the necessity of optimizing b-value for better monitoring and detecting myocardial structural degradation.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionTheme: Adapting MR in a Changing World
 
dc.descriptionTraditional Poster Session - Diffusion & Perfusion - Body Diffusion: no. 1858
 
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 1858
 
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 1858 [How to Cite?]
 
dc.identifier.hkuros207488
 
dc.identifier.urihttp://hdl.handle.net/10722/165199
 
dc.languageeng
 
dc.publisherInternational Society of Magnetic Resonance in Medicine.
 
dc.publisher.placeAustralia
 
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012
 
dc.titleEffect of b-value on DTI sensitivity in revealing myocardial structure degradation in rabbit models with acute myocardium infarction
 
dc.typeConference_Paper
 
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<description.abstract>The free Gaussian process of water diffusion assumed in conventional DTI was found to not apply with increase of diffusion strength. In this study, effect of b-value on detecting myocardial structural alteration was assessed in infarcted rabbit models. Non-monoexponential diffusion manner was confirmed in both infarct and control groups. FA and radial diffusivity were found to alter significantly in infarct and/or adjacent regions, and the sensitivity to detect their statistical differences among all the groups were b-value dependent with the greatest total number of statistical significances occurred at b-values of 750 to 2000 s/mm2. The study demonstrated the important effect of diffusion strength on DTI index characterization and emphasized the necessity of optimizing b-value for better monitoring and detecting myocardial structural degradation.</description.abstract>
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