File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Past dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Study

TitlePast dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Study
Authors
KeywordsChinese
Chronic obstructive lung disease
Coughing
Dust exposure
Dyspnea
Issue Date2012
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/rmed
Citation
Respiratory Medicine, 2012, v. 106 n. 10, p. 1421-1428 How to Cite?
AbstractThe impact of occupational dust and gas/fume exposure on chronic obstructive pulmonary disease (COPD) in developing countries has not been quantified. We examined the relationship between past dust and fume exposure and prevalence of COPD and respiratory symptoms in a cross-sectional analysis of a large Chinese population sample. Participants in the Guangzhou Biobank Cohort Study (n = 8216; 27.3% men, mean age 61.9 +/- 6.8 years) had spirometry and a structured interview including exposures, symptoms, and lifestyle. Self-reported intensity and duration of dust and gas/fume exposure was used to derive cumulative exposure. COPD was diagnosed from spirometry using lower limit of normal based on prediction equations. COPD was associated with high exposure to dust or gas/fume (exposed: 87/1206 v non-exposed: 191/3853; adjusted odds ratio: 1.41; 95% confidence interval (CI) 1.06, 1.87) with no evidence of effect modification by smoking. Respiratory symptoms were associated with exposures to dust and gas/fume, with adjusted odds ratios for chronic cough/phlegm of 1.57 (1.13, 2.17) and 1.39 (1.20, 1.60) for dyspnoea. The overall population attributable fraction for COPD due to occupational exposure was 10.4% (95% CI -0.9%, 19.5%). Occupational dust and gas/fume exposure is associated with an increased prevalence of COPD in this Chinese sample, independent of smoking. The population attributable fraction in Chinese is similar to that in Western populations.
Persistent Identifierhttp://hdl.handle.net/10722/164800
ISSN
2014 Impact Factor: 3.086
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, KBHen_US
dc.contributor.authorYin, Pen_US
dc.contributor.authorJiang, CQen_US
dc.contributor.authorZhang, WSen_US
dc.contributor.authorAdab, Pen_US
dc.contributor.authorMiller, MRen_US
dc.contributor.authorThomas, GNen_US
dc.contributor.authorAyres, JGen_US
dc.contributor.authorLam, THen_US
dc.contributor.authorCheng, KKen_US
dc.date.accessioned2012-09-20T08:09:42Z-
dc.date.available2012-09-20T08:09:42Z-
dc.date.issued2012en_US
dc.identifier.citationRespiratory Medicine, 2012, v. 106 n. 10, p. 1421-1428en_US
dc.identifier.issn0954-6111-
dc.identifier.urihttp://hdl.handle.net/10722/164800-
dc.description.abstractThe impact of occupational dust and gas/fume exposure on chronic obstructive pulmonary disease (COPD) in developing countries has not been quantified. We examined the relationship between past dust and fume exposure and prevalence of COPD and respiratory symptoms in a cross-sectional analysis of a large Chinese population sample. Participants in the Guangzhou Biobank Cohort Study (n = 8216; 27.3% men, mean age 61.9 +/- 6.8 years) had spirometry and a structured interview including exposures, symptoms, and lifestyle. Self-reported intensity and duration of dust and gas/fume exposure was used to derive cumulative exposure. COPD was diagnosed from spirometry using lower limit of normal based on prediction equations. COPD was associated with high exposure to dust or gas/fume (exposed: 87/1206 v non-exposed: 191/3853; adjusted odds ratio: 1.41; 95% confidence interval (CI) 1.06, 1.87) with no evidence of effect modification by smoking. Respiratory symptoms were associated with exposures to dust and gas/fume, with adjusted odds ratios for chronic cough/phlegm of 1.57 (1.13, 2.17) and 1.39 (1.20, 1.60) for dyspnoea. The overall population attributable fraction for COPD due to occupational exposure was 10.4% (95% CI -0.9%, 19.5%). Occupational dust and gas/fume exposure is associated with an increased prevalence of COPD in this Chinese sample, independent of smoking. The population attributable fraction in Chinese is similar to that in Western populations.-
dc.languageengen_US
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/rmed-
dc.relation.ispartofRespiratory Medicineen_US
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in <Journal title>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, [VOL#, ISSUE#, (DATE)] DOI#-
dc.subjectChinese-
dc.subjectChronic obstructive lung disease-
dc.subjectCoughing-
dc.subjectDust exposure-
dc.subjectDyspnea-
dc.titlePast dust and GAS/FUME exposure and COPD in Chinese: the Guangzhou Biobank Cohort Studyen_US
dc.typeArticleen_US
dc.identifier.emailJiang, CQ: jcqiang@yahoo.com.cnen_US
dc.identifier.emailLam, TH: hrmrlth@hkucc.hku.hken_US
dc.identifier.authorityLam, TH=rp00326en_US
dc.identifier.doi10.1016/j.rmed.2012.05.009-
dc.identifier.pmid22795505-
dc.identifier.scopuseid_2-s2.0-84865202412-
dc.identifier.hkuros209802en_US
dc.identifier.volume106en_US
dc.identifier.issue10en_US
dc.identifier.spage1421en_US
dc.identifier.epage1428en_US
dc.identifier.isiWOS:000309147400010-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats