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Article: The association of gamma-glutamyltransferase and C-reactive protein with IFG/IGT in Chinese adults in Qingdao, China

TitleThe association of gamma-glutamyltransferase and C-reactive protein with IFG/IGT in Chinese adults in Qingdao, China
Authors
Issue Date2011
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/cca
Citation
Clinica Chimica Acta, 2011, v. 412 n. 17-18, p. 1658-1661 How to Cite?
AbstractBACKGROUND: Serum gamma-glutamyltransferase (GGT) and C-reactive protein(CRP) have been previously shown to be associated with impaired fasting glucose/impaired glucose tolerance (IFG/IGT), but such an association has not been well verified, and is examined in a non-diabetic Chinese population. METHODS: A population-based cross-sectional study was conducted in 2006 in Qingdao, China. Data of 1143 men and 1689 women aged 35-74 years and free of diabetes at baseline were analyzed. Multivariable logistic regression analysis was performed to estimate the odds ratio (OR) and its 95% confidence interval (CI). RESULTS: Compared with the lowest quartile, the ORs (95%CI) for IFG/IGT corresponding to the highest quartile were 0.89(0.61,1.28) in men and 0.87(0.64,1.18) in women for CRP and 2.12(1.40,3.38) and 1.87(1.32,2.62) for GGT, when the two were fitted simultaneously in a model adjusting for age, school years, alcohol-drinking, smoking, family history of diabetes, systolic blood pressure, waist circumference, triglycerides and high-density lipoprotein. CONCLUSIONS: The elevated GGT, but not CRP, was independently associated with the presence of the IFG/IGT in both genders in this Chinese population.
Persistent Identifierhttp://hdl.handle.net/10722/164794
ISSN
2015 Impact Factor: 2.799
2015 SCImago Journal Rankings: 1.040
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSun, JPen_US
dc.contributor.authorRen, Jen_US
dc.contributor.authorPang, ZCen_US
dc.contributor.authorGao, WGen_US
dc.contributor.authorNan, HRen_US
dc.contributor.authorWang, SJen_US
dc.contributor.authorZhang, Len_US
dc.contributor.authorQiao, Qen_US
dc.date.accessioned2012-09-20T08:09:39Z-
dc.date.available2012-09-20T08:09:39Z-
dc.date.issued2011en_US
dc.identifier.citationClinica Chimica Acta, 2011, v. 412 n. 17-18, p. 1658-1661en_US
dc.identifier.issn0009-8981-
dc.identifier.urihttp://hdl.handle.net/10722/164794-
dc.description.abstractBACKGROUND: Serum gamma-glutamyltransferase (GGT) and C-reactive protein(CRP) have been previously shown to be associated with impaired fasting glucose/impaired glucose tolerance (IFG/IGT), but such an association has not been well verified, and is examined in a non-diabetic Chinese population. METHODS: A population-based cross-sectional study was conducted in 2006 in Qingdao, China. Data of 1143 men and 1689 women aged 35-74 years and free of diabetes at baseline were analyzed. Multivariable logistic regression analysis was performed to estimate the odds ratio (OR) and its 95% confidence interval (CI). RESULTS: Compared with the lowest quartile, the ORs (95%CI) for IFG/IGT corresponding to the highest quartile were 0.89(0.61,1.28) in men and 0.87(0.64,1.18) in women for CRP and 2.12(1.40,3.38) and 1.87(1.32,2.62) for GGT, when the two were fitted simultaneously in a model adjusting for age, school years, alcohol-drinking, smoking, family history of diabetes, systolic blood pressure, waist circumference, triglycerides and high-density lipoprotein. CONCLUSIONS: The elevated GGT, but not CRP, was independently associated with the presence of the IFG/IGT in both genders in this Chinese population.-
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/cca-
dc.relation.ispartofClinica Chimica Actaen_US
dc.subject.meshC-Reactive Protein - metabolism-
dc.subject.meshChromatography, High Pressure Liquid-
dc.subject.meshCross-Sectional Studies-
dc.subject.meshGlucose Tolerance Test-
dc.subject.meshgamma-Glutamyltransferase - metabolism-
dc.titleThe association of gamma-glutamyltransferase and C-reactive protein with IFG/IGT in Chinese adults in Qingdao, Chinaen_US
dc.typeArticleen_US
dc.identifier.emailNan, HR: hnan@hku.hken_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.cca.2011.05.019-
dc.identifier.pmid21624355-
dc.identifier.scopuseid_2-s2.0-79959300609-
dc.identifier.hkuros208041en_US
dc.identifier.volume412en_US
dc.identifier.issue17-18en_US
dc.identifier.spage1658en_US
dc.identifier.epage1661en_US
dc.identifier.isiWOS:000292997100028-
dc.publisher.placeNetherlands-
dc.identifier.citeulike9366492-

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