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- Publisher Website: 10.1159/000341096
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- PMID: 22907195
- WOS: WOS:000309143800008
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Article: Long-term hearing results and otological complications of nasopharyngeal carcinoma patients: comparison between treatment with conventional two-dimensional radiotherapy and intensity-modulated radiotherapy
Title | Long-term hearing results and otological complications of nasopharyngeal carcinoma patients: comparison between treatment with conventional two-dimensional radiotherapy and intensity-modulated radiotherapy |
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Authors | |
Keywords | Antineoplastic agent Aged Bone necrosis Cancer chemotherapy Cancer radiotherapy |
Issue Date | 2012 |
Publisher | S. Karger AG. |
Citation | ORL: Journal for Oto-rhino-laryngology and Its Related Specialties, 2012, v. 74 n. 4, p. 228-233 How to Cite? |
Abstract | OBJECTIVE: To assess the long-term audiological outcome and otological complications of nasopharyngeal carcinoma patients who have received intensity-modulated radiotherapy (IMRT) versus conventional two-dimensional radiotherapy (2 DRT). STUDY DESIGN: Prospective study on the audiological outcome and otological complications 5-9 years after radiotherapy. METHODOLOGY: Patients had pure-tone audiogram before radiotherapy and 5 years after radiotherapy. Otological examination was performed 5-9 years after radiotherapy by an otolaryngologist. RESULTS: There is a significant deterioration of the hearing threshold 5 years after radiotherapy but there is no statistically significant difference in the deterioration of hearing between IMRT and 2 DRT. Six patients in the 2 DRT group and 1 patient in the IMRT group had osteoradionecrosis of the external auditory canal (p = 0.042). CONCLUSION: There are fewer incidences of osteoradionecrosis of the external auditory canal in patients treated with IMRT. There is no difference in bone conduction threshold in patients treated with IMRT or 2 DRT. |
Persistent Identifier | http://hdl.handle.net/10722/163919 |
ISSN | 2023 Impact Factor: 1.5 2023 SCImago Journal Rankings: 0.415 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Tsang, RK | en_US |
dc.contributor.author | Kwong, DL | en_US |
dc.contributor.author | Ho, AC | en_US |
dc.contributor.author | To, VS | en_US |
dc.contributor.author | Ho, WK | en_US |
dc.contributor.author | Wei, WI | en_US |
dc.date.accessioned | 2012-09-20T07:53:09Z | - |
dc.date.available | 2012-09-20T07:53:09Z | - |
dc.date.issued | 2012 | en_US |
dc.identifier.citation | ORL: Journal for Oto-rhino-laryngology and Its Related Specialties, 2012, v. 74 n. 4, p. 228-233 | en_US |
dc.identifier.issn | 0301-1569 | - |
dc.identifier.uri | http://hdl.handle.net/10722/163919 | - |
dc.description.abstract | OBJECTIVE: To assess the long-term audiological outcome and otological complications of nasopharyngeal carcinoma patients who have received intensity-modulated radiotherapy (IMRT) versus conventional two-dimensional radiotherapy (2 DRT). STUDY DESIGN: Prospective study on the audiological outcome and otological complications 5-9 years after radiotherapy. METHODOLOGY: Patients had pure-tone audiogram before radiotherapy and 5 years after radiotherapy. Otological examination was performed 5-9 years after radiotherapy by an otolaryngologist. RESULTS: There is a significant deterioration of the hearing threshold 5 years after radiotherapy but there is no statistically significant difference in the deterioration of hearing between IMRT and 2 DRT. Six patients in the 2 DRT group and 1 patient in the IMRT group had osteoradionecrosis of the external auditory canal (p = 0.042). CONCLUSION: There are fewer incidences of osteoradionecrosis of the external auditory canal in patients treated with IMRT. There is no difference in bone conduction threshold in patients treated with IMRT or 2 DRT. | - |
dc.language | eng | en_US |
dc.publisher | S. Karger AG. | en_US |
dc.relation.ispartof | ORL: Journal for Oto-rhino-laryngology and Its Related Specialties | en_US |
dc.rights | ORL: Journal for Oto-rhino-laryngology and Its Related Specialties. Copyright © S. Karger AG. | en_US |
dc.subject | Antineoplastic agent | - |
dc.subject | Aged | - |
dc.subject | Bone necrosis | - |
dc.subject | Cancer chemotherapy | - |
dc.subject | Cancer radiotherapy | - |
dc.title | Long-term hearing results and otological complications of nasopharyngeal carcinoma patients: comparison between treatment with conventional two-dimensional radiotherapy and intensity-modulated radiotherapy | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tsang, RK: rkytsang@hku.hk | en_US |
dc.identifier.email | Kwong, DL: dlwkwong@hku.hk | en_US |
dc.identifier.email | Ho, AC: aho1@hku.hk | en_US |
dc.identifier.email | To, VS: doctorto@hku.hk | en_US |
dc.identifier.email | Ho, WK: wkho@hkucc.hku.hk | en_US |
dc.identifier.email | Wei, WI: hrmswwi@hku.hk | en_US |
dc.identifier.authority | Tsang, RK=rp01386 | en_US |
dc.identifier.authority | Kwong, DL=rp00414 | en_US |
dc.identifier.authority | To, VS=rp01385 | en_US |
dc.identifier.authority | Wei, WI=rp00323 | en_US |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1159/000341096 | - |
dc.identifier.pmid | 22907195 | - |
dc.identifier.scopus | eid_2-s2.0-84865048392 | - |
dc.identifier.hkuros | 209876 | en_US |
dc.identifier.hkuros | 210070 | - |
dc.identifier.volume | 74 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 228 | en_US |
dc.identifier.epage | 233 | en_US |
dc.identifier.isi | WOS:000309143800008 | - |
dc.publisher.place | Switzerland | - |
dc.identifier.issnl | 0301-1569 | - |