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Conference Paper: Seasonal variation in fibrinolysis in patients with rheumatoid arthritis

TitleSeasonal variation in fibrinolysis in patients with rheumatoid arthritis
Authors
Issue Date1990
Citation
Fibrinolysis, 1990, v. 4 SUPPL. 2, p. 116-117 How to Cite?
AbstractVenous blood samples were taken from 15 patients aged between 28 and 68 years (mean age 49.5) at eight week intervals and at a standard time of day. t-PA and PA1 were measured by chromogenic substrate assays (Kabi). Mean levels of t-PA were found to be high in June, July and August compared to the winter months (P<0.001) and PAI levels were found to be lower in the same three months (P<0.05). These results show that fibrinolytic capacity is reduced in the winter months compared to the summer months of june, July and August in patients with rheumatoid arthritis. Further study is required in normal individuals and in other groups of patients since this could be a contributory factor towards the higher incidence of vasculitis in rheumatoid arthritis and other vascular incidents in the winter months.
Persistent Identifierhttp://hdl.handle.net/10722/163524
ISSN
2003 Impact Factor: 0.5
2000 SCImago Journal Rankings: 0.378

 

DC FieldValueLanguage
dc.contributor.authorMclaren, Men_US
dc.contributor.authorLau, Cen_US
dc.contributor.authorForbes, CDen_US
dc.contributor.authorBelch, JPen_US
dc.date.accessioned2012-09-05T05:37:04Z-
dc.date.available2012-09-05T05:37:04Z-
dc.date.issued1990en_US
dc.identifier.citationFibrinolysis, 1990, v. 4 SUPPL. 2, p. 116-117en_US
dc.identifier.issn0268-9499en_US
dc.identifier.urihttp://hdl.handle.net/10722/163524-
dc.description.abstractVenous blood samples were taken from 15 patients aged between 28 and 68 years (mean age 49.5) at eight week intervals and at a standard time of day. t-PA and PA1 were measured by chromogenic substrate assays (Kabi). Mean levels of t-PA were found to be high in June, July and August compared to the winter months (P<0.001) and PAI levels were found to be lower in the same three months (P<0.05). These results show that fibrinolytic capacity is reduced in the winter months compared to the summer months of june, July and August in patients with rheumatoid arthritis. Further study is required in normal individuals and in other groups of patients since this could be a contributory factor towards the higher incidence of vasculitis in rheumatoid arthritis and other vascular incidents in the winter months.en_US
dc.languageengen_US
dc.relation.ispartofFibrinolysisen_US
dc.titleSeasonal variation in fibrinolysis in patients with rheumatoid arthritisen_US
dc.typeConference_Paperen_US
dc.identifier.emailLau, C:cslau@hku.hken_US
dc.identifier.authorityLau, C=rp01348en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0025087692en_US
dc.identifier.volume4en_US
dc.identifier.issueSUPPL. 2en_US
dc.identifier.spage116en_US
dc.identifier.epage117en_US
dc.identifier.scopusauthoridMcLaren, M=7005471705en_US
dc.identifier.scopusauthoridLau, C=14035682100en_US
dc.identifier.scopusauthoridForbes, CD=7103200817en_US
dc.identifier.scopusauthoridBelch, JP=7101752864en_US

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