File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: OSA and atherosclerosis
  • Basic View
  • Metadata View
  • XML View
TitleOSA and atherosclerosis
 
AuthorsLui, MMS1
Ip, MSM1
 
Issue Date2012
 
PublisherPioneer Bioscience Publishing Company. The Journal's web site is located at http://www.jthoracdis.com/
 
CitationJournal Of Thoracic Disease, 2012, v. 4 n. 2, p. 164-172 [How to Cite?]
DOI: http://dx.doi.org/10.3978/j.issn.2072-1439.2012.01.06
 
AbstractUntreated obstructive sleep apnea (OSA) is increasingly recognized as a risk factor contributing to cardiovascular morbidity and mortality. Research in recent decades has uncovered many components of the complex pathological events leading to the atherosclerotic vascular diseases in OSA, which involve heightened oxidative stress as a result of intermittent hypoxia, vascular inflammation, activation of platelet and coagulation cascades, endothelial dysfunction and ultimately the formation of atherosclerotic plagues. The close association of OSA and conventional cardiovascular risk factors including hypertension, diabetes mellitus, dyslipidemia and obesity adds to the adverse cardiovascular sequelae. Further studies are required to clarify further on the pathophysiological processes, and the effect size of OSA therapy, and other potential preventive strategies.
 
ISSN2072-1439
 
DOIhttp://dx.doi.org/10.3978/j.issn.2072-1439.2012.01.06
 
DC FieldValue
dc.contributor.authorLui, MMS
 
dc.contributor.authorIp, MSM
 
dc.date.accessioned2012-09-05T05:32:18Z
 
dc.date.available2012-09-05T05:32:18Z
 
dc.date.issued2012
 
dc.description.abstractUntreated obstructive sleep apnea (OSA) is increasingly recognized as a risk factor contributing to cardiovascular morbidity and mortality. Research in recent decades has uncovered many components of the complex pathological events leading to the atherosclerotic vascular diseases in OSA, which involve heightened oxidative stress as a result of intermittent hypoxia, vascular inflammation, activation of platelet and coagulation cascades, endothelial dysfunction and ultimately the formation of atherosclerotic plagues. The close association of OSA and conventional cardiovascular risk factors including hypertension, diabetes mellitus, dyslipidemia and obesity adds to the adverse cardiovascular sequelae. Further studies are required to clarify further on the pathophysiological processes, and the effect size of OSA therapy, and other potential preventive strategies.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Thoracic Disease, 2012, v. 4 n. 2, p. 164-172 [How to Cite?]
DOI: http://dx.doi.org/10.3978/j.issn.2072-1439.2012.01.06
 
dc.identifier.doihttp://dx.doi.org/10.3978/j.issn.2072-1439.2012.01.06
 
dc.identifier.epage172
 
dc.identifier.hkuros207018
 
dc.identifier.issn2072-1439
 
dc.identifier.issue2
 
dc.identifier.scopuseid_2-s2.0-84861985896
 
dc.identifier.spage164
 
dc.identifier.urihttp://hdl.handle.net/10722/163495
 
dc.identifier.volume4
 
dc.languageeng
 
dc.publisherPioneer Bioscience Publishing Company. The Journal's web site is located at http://www.jthoracdis.com/
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofJournal of Thoracic Disease
 
dc.titleOSA and atherosclerosis
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Lui, MMS</contributor.author>
<contributor.author>Ip, MSM</contributor.author>
<date.accessioned>2012-09-05T05:32:18Z</date.accessioned>
<date.available>2012-09-05T05:32:18Z</date.available>
<date.issued>2012</date.issued>
<identifier.citation>Journal Of Thoracic Disease, 2012, v. 4 n. 2, p. 164-172</identifier.citation>
<identifier.issn>2072-1439</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/163495</identifier.uri>
<description.abstract>Untreated obstructive sleep apnea (OSA) is increasingly recognized as a risk factor contributing to cardiovascular morbidity and mortality. Research in recent decades has uncovered many components of the complex pathological events leading to the atherosclerotic vascular diseases in OSA, which involve heightened oxidative stress as a result of intermittent hypoxia, vascular inflammation, activation of platelet and coagulation cascades, endothelial dysfunction and ultimately the formation of atherosclerotic plagues. The close association of OSA and conventional cardiovascular risk factors including hypertension, diabetes mellitus, dyslipidemia and obesity adds to the adverse cardiovascular sequelae. Further studies are required to clarify further on the pathophysiological processes, and the effect size of OSA therapy, and other potential preventive strategies.</description.abstract>
<language>eng</language>
<publisher>Pioneer Bioscience Publishing Company. The Journal&apos;s web site is located at http://www.jthoracdis.com/</publisher>
<relation.ispartof>Journal of Thoracic Disease</relation.ispartof>
<title>OSA and atherosclerosis</title>
<type>Article</type>
<description.nature>link_to_subscribed_fulltext</description.nature>
<identifier.doi>10.3978/j.issn.2072-1439.2012.01.06</identifier.doi>
<identifier.scopus>eid_2-s2.0-84861985896</identifier.scopus>
<identifier.hkuros>207018</identifier.hkuros>
<identifier.volume>4</identifier.volume>
<identifier.issue>2</identifier.issue>
<identifier.spage>164</identifier.spage>
<identifier.epage>172</identifier.epage>
<publisher.place>Hong Kong</publisher.place>
</item>
Author Affiliations
  1. The University of Hong Kong