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Article: Influence of left ventricular geometry and function on aortic annular dimensions as assessed with multi-detector row computed tomography: implications for transcatheter aortic valve implantation

TitleInfluence of left ventricular geometry and function on aortic annular dimensions as assessed with multi-detector row computed tomography: implications for transcatheter aortic valve implantation
Authors
Issue Date2011
PublisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/
Citation
European Heart Journal, 2011, v. 32 n. 22, p. 2806-2813 How to Cite?
AbstractAIMS: Evaluate changes in aortic annular dimensions in relation to severe aortic stenosis (AS) and left ventricular (LV) dysfunction. METHODS AND RESULTS: Mean aortic annular diameters and geometries were compared between 90 severe AS patients and 111 controls by multi-detector row computed tomography (MDCT). All severe AS patients were also dichotomized into two groups based on the presence of preserved (>/= 50%) or impaired (<50%) LV ejection fraction (EF). The influence of LV geometry and function on changes in aortic annular dimensions was examined. Patients with severe AS had similar aortic annular dimensions and geometries compared with controls even after correcting for baseline differences in age and body surface area (BSA). However, severe AS patients with LV dysfunction (LVEF <50%) had significantly larger mean aortic annular diameter (26.4 +/- 1.9 vs. 24.5 +/- 2.1 mm, P < 0.001) compared with patients with preserved LVEF. The presence of LV dysfunction, male gender, and larger BSA were independent determinants of a larger aortic annulus on MDCT. CONCLUSION: In severe AS patients, the presence of LV dysfunction, not the presence of severe AS, was an independent determinant of a larger aortic annular diameter.
Persistent Identifierhttp://hdl.handle.net/10722/163421
ISSN
2015 Impact Factor: 15.064
2015 SCImago Journal Rankings: 6.997
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, ACTen_US
dc.contributor.authorYiu, KHen_US
dc.contributor.authorEwe, SHen_US
dc.contributor.authorvan der Kley, Fen_US
dc.contributor.authorBertini, Men_US
dc.contributor.authorde Weger, Aen_US
dc.contributor.authorde Roos, Aen_US
dc.contributor.authorLeung, DYen_US
dc.contributor.authorSchuijf, JDen_US
dc.contributor.authorSchalij, MJen_US
dc.contributor.authorBax, JJen_US
dc.contributor.authorDelgado, Ven_US
dc.date.accessioned2012-09-05T05:31:11Z-
dc.date.available2012-09-05T05:31:11Z-
dc.date.issued2011en_US
dc.identifier.citationEuropean Heart Journal, 2011, v. 32 n. 22, p. 2806-2813en_US
dc.identifier.issn0195-668Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/163421-
dc.description.abstractAIMS: Evaluate changes in aortic annular dimensions in relation to severe aortic stenosis (AS) and left ventricular (LV) dysfunction. METHODS AND RESULTS: Mean aortic annular diameters and geometries were compared between 90 severe AS patients and 111 controls by multi-detector row computed tomography (MDCT). All severe AS patients were also dichotomized into two groups based on the presence of preserved (>/= 50%) or impaired (<50%) LV ejection fraction (EF). The influence of LV geometry and function on changes in aortic annular dimensions was examined. Patients with severe AS had similar aortic annular dimensions and geometries compared with controls even after correcting for baseline differences in age and body surface area (BSA). However, severe AS patients with LV dysfunction (LVEF <50%) had significantly larger mean aortic annular diameter (26.4 +/- 1.9 vs. 24.5 +/- 2.1 mm, P < 0.001) compared with patients with preserved LVEF. The presence of LV dysfunction, male gender, and larger BSA were independent determinants of a larger aortic annulus on MDCT. CONCLUSION: In severe AS patients, the presence of LV dysfunction, not the presence of severe AS, was an independent determinant of a larger aortic annular diameter.en_US
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://eurheartj.oxfordjournals.org/en_US
dc.relation.ispartofEuropean Heart Journalen_US
dc.subject.meshAorta - pathologyen_US
dc.subject.meshAortic Valve - pathology - surgeryen_US
dc.subject.meshAortic Valve Stenosis - pathology - physiopathology - surgeryen_US
dc.subject.meshHeart Valve Prosthesis Implantation - methodsen_US
dc.subject.meshVentricular Dysfunction, Left - pathology - physiopathologyen_US
dc.titleInfluence of left ventricular geometry and function on aortic annular dimensions as assessed with multi-detector row computed tomography: implications for transcatheter aortic valve implantationen_US
dc.typeArticleen_US
dc.identifier.emailNg, ACT: arnoldct@hotmail.comen_US
dc.identifier.emailYiu, KH: khkyiu@hku.hk-
dc.identifier.emailDelgado, V: v.delgado@lumc.nl-
dc.identifier.authorityYiu, KH=rp01490en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1093/eurheartj/ehr237en_US
dc.identifier.pmid21785108-
dc.identifier.scopuseid_2-s2.0-81855190666en_US
dc.identifier.hkuros205941-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-81855190666&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume32en_US
dc.identifier.issue22en_US
dc.identifier.spage2806en_US
dc.identifier.epage2813en_US
dc.identifier.eissn1522-9645-
dc.identifier.isiWOS:000297273500021-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridDelgado, V=24172709900en_US
dc.identifier.scopusauthoridBax, JJ=35379683700en_US
dc.identifier.scopusauthoridSchalij, MJ=7007083597en_US
dc.identifier.scopusauthoridSchuijf, JD=6602555819en_US
dc.identifier.scopusauthoridLeung, DY=7203002860en_US
dc.identifier.scopusauthoridDe Roos, A=35241888000en_US
dc.identifier.scopusauthoridDe Weger, A=35075850200en_US
dc.identifier.scopusauthoridBertini, M=22033600300en_US
dc.identifier.scopusauthoridVan Der Kley, F=26536790300en_US
dc.identifier.scopusauthoridEwe, SH=23993827400en_US
dc.identifier.scopusauthoridYiu, KH=35172267800en_US
dc.identifier.scopusauthoridNg, ACT=15726084000en_US

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