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Article: Official Positions for FRAX ® Clinical Regarding International Differences. From Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX ®

TitleOfficial Positions for FRAX ® Clinical Regarding International Differences. From Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX ®
Authors
Issue Date2011
PublisherElsevier BV. The Journal's web site is located at http://www.iscd.org/Visitors/publications/journal.cfm
Citation
Journal Of Clinical Densitometry, 2011, v. 14 n. 3, p. 240-262 How to Cite?
AbstractOsteoporosis is a serious worldwide epidemic. Increased risk of fractures is the hallmark of the disease and is associated with increased morbidity, mortality and economic burden.FRAX ® is a web-based tool developed by the Sheffield WHO Collaborating Center team, that integrates clinical risk factors, femoral neck BMD, country specific mortality and fracture data and calculates the 10 year fracture probability in order to help health care professionals identify patients who need treatment. However, only 31 countries have a FRAX ® calculator at the time paper was accepted for publication. In the absence of a FRAX ® model for a particular country, it has been suggested to use a surrogate country for which the epidemiology of osteoporosis most closely approximates the index country. More specific recommendations for clinicians in these countries are not available.In North America, concerns have also been raised regarding the assumptions used to construct the US ethnic specific FRAX ® calculators with respect to the correction factors applied to derive fracture probabilities in Blacks, Asians and Hispanics in comparison to Whites. In addition, questions were raised about calculating fracture risk in other ethnic groups e.g., Native Americans and First Canadians.In order to provide additional guidance to clinicians, a FRAX ® International Task Force was formed to address specific questions raised by physicians in countries without FRAX ® calculators and seeking to integrate FRAX ® into their clinical practice. The main questions that the task force tried to answer were the following:1.What is the evidence supporting ethnic and sex specific adjustments for fracture incidence rates in Blacks, Hispanics and Asians-2.What data exist for other groups, e.g., Native Americans, First Nations Canadians-3.Are there secular changes in fracture rates-4.What are the requirements for the construction of a FRAX ® calculator? And what are the desirable/optimal characteristics of the data-5.What do I do if my country does not have a FRAX ® calculator? The Task Force members conducted appropriate literature reviews and developed preliminary statements that were discussed and graded by a panel of experts at the ISCD-IOF joint conference. The statements approved by the panel of experts are discussed in the current paper. © 2011.
Persistent Identifierhttp://hdl.handle.net/10722/163388
ISSN
2015 Impact Factor: 2.644
2015 SCImago Journal Rankings: 0.942
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCauley, JAen_US
dc.contributor.authorElHajj Fuleihan, Gen_US
dc.contributor.authorArabi, Aen_US
dc.contributor.authorFujiwara, Sen_US
dc.contributor.authorRagiEis, Sen_US
dc.contributor.authorCalderon, Aen_US
dc.contributor.authorChionh, SBen_US
dc.contributor.authorChen, Zen_US
dc.contributor.authorCurtis, JRen_US
dc.contributor.authorDanielson, MEen_US
dc.contributor.authorHanley, DAen_US
dc.contributor.authorKroger, Hen_US
dc.contributor.authorKung, AWCen_US
dc.contributor.authorLesnyak, Oen_US
dc.contributor.authorNieves, Jen_US
dc.contributor.authorPluskiewicz, Wen_US
dc.contributor.authorEl Rassi, Ren_US
dc.contributor.authorSilverman, Sen_US
dc.contributor.authorSchott, AMen_US
dc.contributor.authorRizzoli, Ren_US
dc.contributor.authorLuckey, Men_US
dc.date.accessioned2012-09-05T05:30:49Z-
dc.date.available2012-09-05T05:30:49Z-
dc.date.issued2011en_US
dc.identifier.citationJournal Of Clinical Densitometry, 2011, v. 14 n. 3, p. 240-262en_US
dc.identifier.issn1094-6950en_US
dc.identifier.urihttp://hdl.handle.net/10722/163388-
dc.description.abstractOsteoporosis is a serious worldwide epidemic. Increased risk of fractures is the hallmark of the disease and is associated with increased morbidity, mortality and economic burden.FRAX ® is a web-based tool developed by the Sheffield WHO Collaborating Center team, that integrates clinical risk factors, femoral neck BMD, country specific mortality and fracture data and calculates the 10 year fracture probability in order to help health care professionals identify patients who need treatment. However, only 31 countries have a FRAX ® calculator at the time paper was accepted for publication. In the absence of a FRAX ® model for a particular country, it has been suggested to use a surrogate country for which the epidemiology of osteoporosis most closely approximates the index country. More specific recommendations for clinicians in these countries are not available.In North America, concerns have also been raised regarding the assumptions used to construct the US ethnic specific FRAX ® calculators with respect to the correction factors applied to derive fracture probabilities in Blacks, Asians and Hispanics in comparison to Whites. In addition, questions were raised about calculating fracture risk in other ethnic groups e.g., Native Americans and First Canadians.In order to provide additional guidance to clinicians, a FRAX ® International Task Force was formed to address specific questions raised by physicians in countries without FRAX ® calculators and seeking to integrate FRAX ® into their clinical practice. The main questions that the task force tried to answer were the following:1.What is the evidence supporting ethnic and sex specific adjustments for fracture incidence rates in Blacks, Hispanics and Asians-2.What data exist for other groups, e.g., Native Americans, First Nations Canadians-3.Are there secular changes in fracture rates-4.What are the requirements for the construction of a FRAX ® calculator? And what are the desirable/optimal characteristics of the data-5.What do I do if my country does not have a FRAX ® calculator? The Task Force members conducted appropriate literature reviews and developed preliminary statements that were discussed and graded by a panel of experts at the ISCD-IOF joint conference. The statements approved by the panel of experts are discussed in the current paper. © 2011.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.iscd.org/Visitors/publications/journal.cfmen_US
dc.relation.ispartofJournal of Clinical Densitometryen_US
dc.subject.meshAfrican Continental Ancestry Groupen_US
dc.subject.meshAsian Continental Ancestry Groupen_US
dc.subject.meshBone Densityen_US
dc.subject.meshDiagnosis, Computer-Assisteden_US
dc.subject.meshFemur Neck - Pathology - Radiographyen_US
dc.subject.meshHip Fractures - Diagnosis - Ethnologyen_US
dc.subject.meshHispanic Americansen_US
dc.subject.meshHumansen_US
dc.subject.meshOsteoporotic Fractures - Diagnosis - Ethnologyen_US
dc.subject.meshRisk Assessmenten_US
dc.titleOfficial Positions for FRAX ® Clinical Regarding International Differences. From Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX ®en_US
dc.typeArticleen_US
dc.identifier.emailKung, AWC:awckung@hku.hken_US
dc.identifier.authorityKung, AWC=rp00368en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.jocd.2011.05.015en_US
dc.identifier.pmid21810532en_US
dc.identifier.scopuseid_2-s2.0-79960904962en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79960904962&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume14en_US
dc.identifier.issue3en_US
dc.identifier.spage240en_US
dc.identifier.epage262en_US
dc.identifier.isiWOS:000293989900012-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridCauley, JA=35373878900en_US
dc.identifier.scopusauthoridElHajj Fuleihan, G=6603917520en_US
dc.identifier.scopusauthoridArabi, A=8377894100en_US
dc.identifier.scopusauthoridFujiwara, S=7401827353en_US
dc.identifier.scopusauthoridRagiEis, S=14069129600en_US
dc.identifier.scopusauthoridCalderon, A=37030668200en_US
dc.identifier.scopusauthoridChionh, SB=6508361525en_US
dc.identifier.scopusauthoridChen, Z=35368333000en_US
dc.identifier.scopusauthoridCurtis, JR=35292050600en_US
dc.identifier.scopusauthoridDanielson, ME=7006273891en_US
dc.identifier.scopusauthoridHanley, DA=7103269302en_US
dc.identifier.scopusauthoridKroger, H=7101716365en_US
dc.identifier.scopusauthoridKung, AWC=7102322339en_US
dc.identifier.scopusauthoridLesnyak, O=6602937935en_US
dc.identifier.scopusauthoridNieves, J=7006240725en_US
dc.identifier.scopusauthoridPluskiewicz, W=7006946700en_US
dc.identifier.scopusauthoridEl Rassi, R=24471229700en_US
dc.identifier.scopusauthoridSilverman, S=7202729055en_US
dc.identifier.scopusauthoridSchott, AM=7004534590en_US
dc.identifier.scopusauthoridRizzoli, R=7102794196en_US
dc.identifier.scopusauthoridLuckey, M=7003555781en_US

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