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Article: Advances in research of cancer stem cells

TitleAdvances in research of cancer stem cells
Authors
KeywordsCancer Stem Cells
Literature Review
Neoplasms
Stem Cell
Issue Date2009
Citation
Chinese Journal Of Cancer Prevention And Treatment, 2009, v. 16 n. 24, p. 1973-1976 How to Cite?
AbstractOBJECTIVE: To summarize the advances in the researches about cancer stem cells in last 5 years. METHODS: With the keywords "neoplasms, stem cell and cancer stem cells", 2 760 papers published from Jan 1979 to Dec 2008 were searched in the Pubmed databases. Adoptive standards: 1) the surface markers, drug-resistance mechanism and signal transduction pathways of cancer stem cells. 2) the origin of cancer stem cells. 3) cancer stem cells and clinical oncology. According to the adoptive standards, 33 top-quality papers were chosen for reviewing. RESULTS: Cancer stem cells have the properties of self-renewal and differentiation, with special cell surface markers and drug-resistance. The signal transduction pathways of cancer stem cells including Wnt, Notch, Hedgehog and Bmi-1 were abnormal. Cancer stem cells are the origin of malignant tumor's growth, recurrence and metastasis, having been the target of anti-cancer research. CONCLUSIONS: Rapid progress has been made in the research about cancer stem cells. The thorough study on cancer stem cells is significant for the diagnosis, treatment and prognosis evaluation of malignant tumor. The theory of cancer stem cells will change the current cancer diagnosis and treatment model.
Persistent Identifierhttp://hdl.handle.net/10722/163321
ISSN
2015 SCImago Journal Rankings: 0.104
References

 

DC FieldValueLanguage
dc.contributor.authorSun, JCen_US
dc.contributor.authorLian, QZen_US
dc.contributor.authorXia, JCen_US
dc.date.accessioned2012-09-05T05:30:00Z-
dc.date.available2012-09-05T05:30:00Z-
dc.date.issued2009en_US
dc.identifier.citationChinese Journal Of Cancer Prevention And Treatment, 2009, v. 16 n. 24, p. 1973-1976en_US
dc.identifier.issn1673-5269en_US
dc.identifier.urihttp://hdl.handle.net/10722/163321-
dc.description.abstractOBJECTIVE: To summarize the advances in the researches about cancer stem cells in last 5 years. METHODS: With the keywords "neoplasms, stem cell and cancer stem cells", 2 760 papers published from Jan 1979 to Dec 2008 were searched in the Pubmed databases. Adoptive standards: 1) the surface markers, drug-resistance mechanism and signal transduction pathways of cancer stem cells. 2) the origin of cancer stem cells. 3) cancer stem cells and clinical oncology. According to the adoptive standards, 33 top-quality papers were chosen for reviewing. RESULTS: Cancer stem cells have the properties of self-renewal and differentiation, with special cell surface markers and drug-resistance. The signal transduction pathways of cancer stem cells including Wnt, Notch, Hedgehog and Bmi-1 were abnormal. Cancer stem cells are the origin of malignant tumor's growth, recurrence and metastasis, having been the target of anti-cancer research. CONCLUSIONS: Rapid progress has been made in the research about cancer stem cells. The thorough study on cancer stem cells is significant for the diagnosis, treatment and prognosis evaluation of malignant tumor. The theory of cancer stem cells will change the current cancer diagnosis and treatment model.en_US
dc.languageengen_US
dc.relation.ispartofChinese Journal of Cancer Prevention and Treatmenten_US
dc.subjectCancer Stem Cellsen_US
dc.subjectLiterature Reviewen_US
dc.subjectNeoplasmsen_US
dc.subjectStem Cellen_US
dc.titleAdvances in research of cancer stem cellsen_US
dc.typeArticleen_US
dc.identifier.emailLian, QZ:qzlian@hkucc.hku.hken_US
dc.identifier.authorityLian, QZ=rp00267en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-77953457626en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953457626&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume16en_US
dc.identifier.issue24en_US
dc.identifier.spage1973en_US
dc.identifier.epage1976en_US
dc.identifier.scopusauthoridSun, JC=34868948200en_US
dc.identifier.scopusauthoridLian, QZ=7003399023en_US
dc.identifier.scopusauthoridXia, JC=7402327355en_US

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