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Article: Disorders of glucose metabolism in sleep-disordered breathing

TitleDisorders of glucose metabolism in sleep-disordered breathing
Authors
Issue Date2010
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/cchm
Citation
Clinics In Chest Medicine, 2010, v. 31 n. 2, p. 271-285 How to Cite?
AbstractDespite proliferating literature, the exact relationship between obstructive sleep apnea (OSA) and alterations in glucose metabolism is still controversial. There is growing evidence to suggest that OSA imposes adverse effects on glucose metabolism, but the translation into clinical effect is not well delineated. Many potential mechanisms are being explored, mostly relating to peripheral tissue response to insulin and more recently regarding pancreatic β cell function of insulin secretion. The effect of OSA on glucose metabolism is likely to be influenced by many personal characteristics. Age, degree of adiposity, lifestyle, comorbidities, and even the stage of glucose disorder itself may modify the relationship between OSA and glucose metabolism. In the biologic system of the human body, all these interact to culminate in clinically relevant outcomes. © 2010 Elsevier Inc.
Persistent Identifierhttp://hdl.handle.net/10722/163317
ISSN
2015 Impact Factor: 2.359
2015 SCImago Journal Rankings: 1.064
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLui, MMSen_US
dc.contributor.authorIp, MSMen_US
dc.date.accessioned2012-09-05T05:29:58Z-
dc.date.available2012-09-05T05:29:58Z-
dc.date.issued2010en_US
dc.identifier.citationClinics In Chest Medicine, 2010, v. 31 n. 2, p. 271-285en_US
dc.identifier.issn0272-5231en_US
dc.identifier.urihttp://hdl.handle.net/10722/163317-
dc.description.abstractDespite proliferating literature, the exact relationship between obstructive sleep apnea (OSA) and alterations in glucose metabolism is still controversial. There is growing evidence to suggest that OSA imposes adverse effects on glucose metabolism, but the translation into clinical effect is not well delineated. Many potential mechanisms are being explored, mostly relating to peripheral tissue response to insulin and more recently regarding pancreatic β cell function of insulin secretion. The effect of OSA on glucose metabolism is likely to be influenced by many personal characteristics. Age, degree of adiposity, lifestyle, comorbidities, and even the stage of glucose disorder itself may modify the relationship between OSA and glucose metabolism. In the biologic system of the human body, all these interact to culminate in clinically relevant outcomes. © 2010 Elsevier Inc.en_US
dc.languageengen_US
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/cchmen_US
dc.relation.ispartofClinics in Chest Medicineen_US
dc.subject.meshAnoxia - Physiopathologyen_US
dc.subject.meshAutonomic Nervous System - Physiopathologyen_US
dc.subject.meshBlood Glucose - Analysisen_US
dc.subject.meshContinuous Positive Airway Pressureen_US
dc.subject.meshCytokines - Metabolismen_US
dc.subject.meshDiabetes Mellitus - Metabolismen_US
dc.subject.meshDiabetes Mellitus, Type 2 - Metabolismen_US
dc.subject.meshFatty Acid-Binding Proteins - Physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulin Resistanceen_US
dc.subject.meshSleep Apnea Syndromes - Metabolismen_US
dc.subject.meshSleep Apnea, Obstructive - Metabolism - Therapyen_US
dc.subject.meshSleep Deprivation - Physiopathologyen_US
dc.titleDisorders of glucose metabolism in sleep-disordered breathingen_US
dc.typeArticleen_US
dc.identifier.emailIp, MSM:msmip@hku.hken_US
dc.identifier.authorityIp, MSM=rp00347en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ccm.2010.02.001en_US
dc.identifier.pmid20488286-
dc.identifier.scopuseid_2-s2.0-77952928098en_US
dc.identifier.hkuros179241-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77952928098&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume31en_US
dc.identifier.issue2en_US
dc.identifier.spage271en_US
dc.identifier.epage285en_US
dc.identifier.isiWOS:000278868900008-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLui, MMS=26027035000en_US
dc.identifier.scopusauthoridIp, MSM=7102423259en_US

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