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Article: Electrocardiographic algorithm to identify the optimal target ablation site for idiopathic right ventricular outflow tract ventricular premature contraction

TitleElectrocardiographic algorithm to identify the optimal target ablation site for idiopathic right ventricular outflow tract ventricular premature contraction
Authors
Issue Date2009
PublisherOxford University Press. The Journal's web site is located at http://europace.oxfordjournals.org/
Citation
Europace, 2009, v. 11 n. 9, p. 1214-1220 How to Cite?
AbstractAimsSeveral electrocardiographic (ECG) algorithms have been developed to identify the site of origin of ventricular premature contractions (VPCs) from right ventricular outflow tract (RVOT) based on pacemapping; however, their accuracy remains unclear.Methods and resultsWe evaluated the accuracy of these algorithms in 52 consecutive patients (31 female, mean age 42.6 ± 14.6 years) with successful radiofrequency ablation of RVOT-VPC as guided by 3D electroanatomical non-contact mapping (Ensite, St Jude Medical, USA) and compared with a newly proposed ECG algorithm. As guided by 3D electroanatomical mapping, the successful ablation sites of RVOT-VPC were RVOT septum (n = 31), RVOT free wall (n = 19), and His region (n = 2). Retrospective evaluation in the initial 39 patients shows that the overall positive prediction value to identify a successful ablation site of this newly proposed ECG algorithm is 77.3 and is higher than the 73.3 by Ito et al., 73.3 by Joshi et al., and 53.8 by Dixit et al. (P > 0.05). Prospective evaluation in the subsequent 13 patients also demonstrate similar high overall sensitivity (79.0), specificity (92.7), and positive prediction value (88.2) to identify a successful ablation site with this newly proposed ECG algorithm.ConclusionOn the basis of detail 3D electroanatomical mapping of successful ablation sites, a newly proposed ECG algorithm was developed to improve the sensitivity, specificity, and positive prediction value in identification of targeted ablation sites for RVOT-VPC.
Persistent Identifierhttp://hdl.handle.net/10722/163275
ISSN
2015 Impact Factor: 4.021
2015 SCImago Journal Rankings: 2.201
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, Fen_US
dc.contributor.authorChen, Men_US
dc.contributor.authorYang, Ben_US
dc.contributor.authorJu, Wen_US
dc.contributor.authorChen, Hen_US
dc.contributor.authorYu, Jen_US
dc.contributor.authorLau, CPen_US
dc.contributor.authorCao, Ken_US
dc.contributor.authorTse, HFen_US
dc.date.accessioned2012-09-05T05:29:33Z-
dc.date.available2012-09-05T05:29:33Z-
dc.date.issued2009en_US
dc.identifier.citationEuropace, 2009, v. 11 n. 9, p. 1214-1220en_US
dc.identifier.issn1099-5129en_US
dc.identifier.urihttp://hdl.handle.net/10722/163275-
dc.description.abstractAimsSeveral electrocardiographic (ECG) algorithms have been developed to identify the site of origin of ventricular premature contractions (VPCs) from right ventricular outflow tract (RVOT) based on pacemapping; however, their accuracy remains unclear.Methods and resultsWe evaluated the accuracy of these algorithms in 52 consecutive patients (31 female, mean age 42.6 ± 14.6 years) with successful radiofrequency ablation of RVOT-VPC as guided by 3D electroanatomical non-contact mapping (Ensite, St Jude Medical, USA) and compared with a newly proposed ECG algorithm. As guided by 3D electroanatomical mapping, the successful ablation sites of RVOT-VPC were RVOT septum (n = 31), RVOT free wall (n = 19), and His region (n = 2). Retrospective evaluation in the initial 39 patients shows that the overall positive prediction value to identify a successful ablation site of this newly proposed ECG algorithm is 77.3 and is higher than the 73.3 by Ito et al., 73.3 by Joshi et al., and 53.8 by Dixit et al. (P > 0.05). Prospective evaluation in the subsequent 13 patients also demonstrate similar high overall sensitivity (79.0), specificity (92.7), and positive prediction value (88.2) to identify a successful ablation site with this newly proposed ECG algorithm.ConclusionOn the basis of detail 3D electroanatomical mapping of successful ablation sites, a newly proposed ECG algorithm was developed to improve the sensitivity, specificity, and positive prediction value in identification of targeted ablation sites for RVOT-VPC.en_US
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://europace.oxfordjournals.org/en_US
dc.relation.ispartofEuropaceen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAlgorithmsen_US
dc.subject.meshBody Surface Potential Mapping - Methodsen_US
dc.subject.meshCatheter Ablation - Methodsen_US
dc.subject.meshElectrocardiography - Methodsen_US
dc.subject.meshHeart Conduction System - Surgeryen_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshReproducibility Of Resultsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshSurgery, Computer-Assisted - Methodsen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVentricular Outflow Obstruction - Complications - Diagnosis - Surgeryen_US
dc.subject.meshVentricular Premature Complexes - Diagnosis - Etiology - Surgeryen_US
dc.subject.meshYoung Adulten_US
dc.titleElectrocardiographic algorithm to identify the optimal target ablation site for idiopathic right ventricular outflow tract ventricular premature contractionen_US
dc.typeArticleen_US
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_US
dc.identifier.authorityTse, HF=rp00428en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1093/europace/eup231en_US
dc.identifier.pmid19706640-
dc.identifier.scopuseid_2-s2.0-70349437070en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70349437070&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume11en_US
dc.identifier.issue9en_US
dc.identifier.spage1214en_US
dc.identifier.epage1220en_US
dc.identifier.isiWOS:000269961600017-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridZhang, F=36140901800en_US
dc.identifier.scopusauthoridChen, M=7406352614en_US
dc.identifier.scopusauthoridYang, B=7404472488en_US
dc.identifier.scopusauthoridJu, W=34771294900en_US
dc.identifier.scopusauthoridChen, H=35298451700en_US
dc.identifier.scopusauthoridYu, J=7405525088en_US
dc.identifier.scopusauthoridLau, CP=7401968501en_US
dc.identifier.scopusauthoridCao, K=7102713181en_US
dc.identifier.scopusauthoridTse, HF=7006070805en_US

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