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Article: A review of surrogate markers for atherosclerosis: Flow mediated dilatation; carotid intima media thickness; pulse wave velocity; ankle brachial index
Title | A review of surrogate markers for atherosclerosis: Flow mediated dilatation; carotid intima media thickness; pulse wave velocity; ankle brachial index |
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Authors | |
Keywords | Ankle Brachial Index Atherosclerosis Carotid Intima-Media Thickness Flow-Mediated Dilatation Pulse Wave Velocity Surrogate Marker |
Issue Date | 2008 |
Publisher | Bentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/vdp/index.htm |
Citation | Vascular Disease Prevention, 2008, v. 5 n. 4, p. 234-245 How to Cite? |
Abstract | Atherosclerotic disease is a major cause of morbidity and mortality. The early detection of preclinical atherosclerosis with non-invasive tools has become paramount in order to identify the vulnerable patient and provide aggressive prevention measures. A valid surrogate marker should not only be proven to correlate with underlying atherosclerosis but also needs to be accurate, reproducible and inexpensive. There are currently a number of methods that are widely used for the detection of preclinical atherosclerosis. In this review, we chose 4 methods for discussion namely, (1) Flow-mediated dilatation, (2) Carotid intima media thickness, (3) Pulse wave velocity, and, (4) Ankle brachial index. Clinical evidence concerning their detection of underlying atherosclerosis and their predictive value of cardiovascular events together with their individual drawbacks is discussed. © 2008 Bentham Science Publishers Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/163209 |
ISSN | |
References |
DC Field | Value | Language |
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dc.contributor.author | Yiu, KH | en_US |
dc.contributor.author | Lau, KK | en_US |
dc.contributor.author | Lau, CP | en_US |
dc.contributor.author | Tse, HF | en_US |
dc.date.accessioned | 2012-09-05T05:28:46Z | - |
dc.date.available | 2012-09-05T05:28:46Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Vascular Disease Prevention, 2008, v. 5 n. 4, p. 234-245 | en_US |
dc.identifier.issn | 1567-2700 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/163209 | - |
dc.description.abstract | Atherosclerotic disease is a major cause of morbidity and mortality. The early detection of preclinical atherosclerosis with non-invasive tools has become paramount in order to identify the vulnerable patient and provide aggressive prevention measures. A valid surrogate marker should not only be proven to correlate with underlying atherosclerosis but also needs to be accurate, reproducible and inexpensive. There are currently a number of methods that are widely used for the detection of preclinical atherosclerosis. In this review, we chose 4 methods for discussion namely, (1) Flow-mediated dilatation, (2) Carotid intima media thickness, (3) Pulse wave velocity, and, (4) Ankle brachial index. Clinical evidence concerning their detection of underlying atherosclerosis and their predictive value of cardiovascular events together with their individual drawbacks is discussed. © 2008 Bentham Science Publishers Ltd. | en_US |
dc.language | eng | en_US |
dc.publisher | Bentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/vdp/index.htm | en_US |
dc.relation.ispartof | Vascular Disease Prevention | en_US |
dc.subject | Ankle Brachial Index | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Carotid Intima-Media Thickness | en_US |
dc.subject | Flow-Mediated Dilatation | en_US |
dc.subject | Pulse Wave Velocity | en_US |
dc.subject | Surrogate Marker | en_US |
dc.title | A review of surrogate markers for atherosclerosis: Flow mediated dilatation; carotid intima media thickness; pulse wave velocity; ankle brachial index | en_US |
dc.type | Article | en_US |
dc.identifier.email | Yiu, KH:khkyiu@hku.hk | en_US |
dc.identifier.email | Lau, KK:gkklau@hku.hk | en_US |
dc.identifier.email | Tse, HF:hftse@hkucc.hku.hk | en_US |
dc.identifier.authority | Yiu, KH=rp01490 | en_US |
dc.identifier.authority | Lau, KK=rp01499 | en_US |
dc.identifier.authority | Tse, HF=rp00428 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.scopus | eid_2-s2.0-55749102118 | en_US |
dc.identifier.hkuros | 140858 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-55749102118&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 234 | en_US |
dc.identifier.epage | 245 | en_US |
dc.publisher.place | Netherlands | en_US |
dc.identifier.scopusauthorid | Yiu, KH=35172267800 | en_US |
dc.identifier.scopusauthorid | Lau, KK=22635159600 | en_US |
dc.identifier.scopusauthorid | Lau, CP=7401968501 | en_US |
dc.identifier.scopusauthorid | Tse, HF=7006070805 | en_US |
dc.identifier.issnl | 1567-2700 | - |