Article: Onset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
AuthorsWong, WM1
Lai, KC1
Lam, KF1
Hui, WM1
Huang, JQ1
Xia, HHX1
Hu, WHC1
Lam, CLK1
Chan, CK1
Lam, SK1
Wong, BCY1
Issue Date2004
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
CitationAlimentary Pharmacology And Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
AbstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
ISSN0269-2813
2011 Impact Factor: 3.769
2011 SCImago Journal Rankings: 0.338
DOIhttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorWong, WM
dc.contributor.authorLai, KC
dc.contributor.authorLam, KF
dc.contributor.authorHui, WM
dc.contributor.authorHuang, JQ
dc.contributor.authorXia, HHX
dc.contributor.authorHu, WHC
dc.contributor.authorLam, CLK
dc.contributor.authorChan, CK
dc.contributor.authorLam, SK
dc.contributor.authorWong, BCY
dc.date.accessioned2012-09-05T05:28:34Z
dc.date.available2012-09-05T05:28:34Z
dc.date.issued2004
dc.description.abstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
dc.identifier.doihttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
dc.identifier.epage812
dc.identifier.issn0269-2813
2011 Impact Factor: 3.769
2011 SCImago Journal Rankings: 0.338
dc.identifier.issue7
dc.identifier.pmid15379841
dc.identifier.scopuseid_2-s2.0-4844224394
dc.identifier.spage803
dc.identifier.urihttp://hdl.handle.net/10722/163189
dc.identifier.volume20
dc.languageeng
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
dc.publisher.placeUnited Kingdom
dc.relation.ispartofAlimentary Pharmacology and Therapeutics
dc.relation.referencesReferences in Scopus
dc.subject.meshAdult
dc.subject.meshChina - Epidemiology
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshGastroesophageal Reflux - Epidemiology
dc.subject.meshHealth Services - Utilization
dc.subject.meshHealth Surveys
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshPatient Acceptance Of Health Care - Statistics & Numerical Data
dc.subject.meshPrevalence
dc.subject.meshRegression Analysis
dc.titleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong