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Article: Onset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
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TitleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
 
AuthorsWong, WM1
Lai, KC1
Lam, KF1
Hui, WM1
Huang, JQ1
Xia, HHX1
Hu, WHC1
Lam, CLK1
Chan, CK1
Lam, SK1
Wong, BCY1 1
 
Issue Date2004
 
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
 
CitationAlimentary Pharmacology and Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
AbstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
 
ISSN0269-2813
2012 Impact Factor: 4.548
2012 SCImago Journal Rankings: 1.689
 
DOIhttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorWong, WM
 
dc.contributor.authorLai, KC
 
dc.contributor.authorLam, KF
 
dc.contributor.authorHui, WM
 
dc.contributor.authorHuang, JQ
 
dc.contributor.authorXia, HHX
 
dc.contributor.authorHu, WHC
 
dc.contributor.authorLam, CLK
 
dc.contributor.authorChan, CK
 
dc.contributor.authorLam, SK
 
dc.contributor.authorWong, BCY
 
dc.date.accessioned2012-09-05T05:28:34Z
 
dc.date.available2012-09-05T05:28:34Z
 
dc.date.issued2004
 
dc.description.abstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationAlimentary Pharmacology and Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
dc.identifier.epage812
 
dc.identifier.hkuros103623
 
dc.identifier.issn0269-2813
2012 Impact Factor: 4.548
2012 SCImago Journal Rankings: 1.689
 
dc.identifier.issue7
 
dc.identifier.pmid15379841
 
dc.identifier.scopuseid_2-s2.0-4844224394
 
dc.identifier.spage803
 
dc.identifier.urihttp://hdl.handle.net/10722/163189
 
dc.identifier.volume20
 
dc.languageeng
 
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofAlimentary Pharmacology and Therapeutics
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdult
 
dc.subject.meshChina - Epidemiology
 
dc.subject.meshFemale
 
dc.subject.meshFollow-Up Studies
 
dc.subject.meshGastroesophageal Reflux - Epidemiology
 
dc.subject.meshHealth Services - Utilization
 
dc.subject.meshHealth Surveys
 
dc.subject.meshHumans
 
dc.subject.meshMale
 
dc.subject.meshPatient Acceptance Of Health Care - Statistics & Numerical Data
 
dc.subject.meshPrevalence
 
dc.subject.meshRegression Analysis
 
dc.titleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong