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Article: Onset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
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TitleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
 
AuthorsWong, WM1
Lai, KC1
Lam, KF1
Hui, WM1
Huang, JQ1
Xia, HHX1
Hu, WHC1
Lam, CLK1
Chan, CK1
Lam, SK1
Wong, BCY1
 
Issue Date2004
 
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
 
CitationAlimentary Pharmacology and Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
AbstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
 
ISSN0269-2813
2013 Impact Factor: 5.478
2013 SCImago Journal Rankings: 2.609
 
DOIhttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorWong, WM
 
dc.contributor.authorLai, KC
 
dc.contributor.authorLam, KF
 
dc.contributor.authorHui, WM
 
dc.contributor.authorHuang, JQ
 
dc.contributor.authorXia, HHX
 
dc.contributor.authorHu, WHC
 
dc.contributor.authorLam, CLK
 
dc.contributor.authorChan, CK
 
dc.contributor.authorLam, SK
 
dc.contributor.authorWong, BCY
 
dc.date.accessioned2012-09-05T05:28:34Z
 
dc.date.available2012-09-05T05:28:34Z
 
dc.date.issued2004
 
dc.description.abstractBackground: The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. Aim: To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. Methods: A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. Results: A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (≥ monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastrooesophageal reflux disease; while the frequency of acid regurgitation (OR: 0.35, 95% CI: 0.17-0.70) and use of antisecretory therapy (OR: 0.50, 95% CI: 0.28-0.89) were associated with the disappearance of gastrooesophageal reflux disease. Conclusion: The prevalence of gastro-oesophageal reflux disease is stable over 1 year. Higher anxiety score and higher educational level were associated with the onset of gastro-oesophageal reflux disease, while lower frequency of reflux symptoms and infrequent use of antisecretory therapy were associated with the disappearance of gastro-oesophageal reflux disease in a Chinese population.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationAlimentary Pharmacology and Therapeutics, 2004, v. 20 n. 7, p. 803-812 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
dc.identifier.doihttp://dx.doi.org/10.1111/j.1365-2036.2004.02198.x
 
dc.identifier.epage812
 
dc.identifier.hkuros103623
 
dc.identifier.issn0269-2813
2013 Impact Factor: 5.478
2013 SCImago Journal Rankings: 2.609
 
dc.identifier.issue7
 
dc.identifier.pmid15379841
 
dc.identifier.scopuseid_2-s2.0-4844224394
 
dc.identifier.spage803
 
dc.identifier.urihttp://hdl.handle.net/10722/163189
 
dc.identifier.volume20
 
dc.languageeng
 
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofAlimentary Pharmacology and Therapeutics
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdult
 
dc.subject.meshChina - Epidemiology
 
dc.subject.meshFemale
 
dc.subject.meshFollow-Up Studies
 
dc.subject.meshGastroesophageal Reflux - Epidemiology
 
dc.subject.meshHealth Services - Utilization
 
dc.subject.meshHealth Surveys
 
dc.subject.meshHumans
 
dc.subject.meshMale
 
dc.subject.meshPatient Acceptance Of Health Care - Statistics & Numerical Data
 
dc.subject.meshPrevalence
 
dc.subject.meshRegression Analysis
 
dc.titleOnset and disappearance of reflux symptoms in a Chinese population: A 1-year follow-up study
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong